5F4S

Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with FBP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005988	biological_process	lactose metabolic process
A	0009024	molecular_function	tagatose-6-phosphate kinase activity
A	0009025	molecular_function	tagatose-bisphosphate aldolase activity
A	0016829	molecular_function	lyase activity
A	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
A	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
A	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
A	2001059	biological_process	D-tagatose 6-phosphate catabolic process
B	0003824	molecular_function	catalytic activity
B	0005988	biological_process	lactose metabolic process
B	0009024	molecular_function	tagatose-6-phosphate kinase activity
B	0009025	molecular_function	tagatose-bisphosphate aldolase activity
B	0016829	molecular_function	lyase activity
B	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
B	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
B	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
B	2001059	biological_process	D-tagatose 6-phosphate catabolic process
C	0003824	molecular_function	catalytic activity
C	0005988	biological_process	lactose metabolic process
C	0009024	molecular_function	tagatose-6-phosphate kinase activity
C	0009025	molecular_function	tagatose-bisphosphate aldolase activity
C	0016829	molecular_function	lyase activity
C	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
C	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
C	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
C	2001059	biological_process	D-tagatose 6-phosphate catabolic process
D	0003824	molecular_function	catalytic activity
D	0005988	biological_process	lactose metabolic process
D	0009024	molecular_function	tagatose-6-phosphate kinase activity
D	0009025	molecular_function	tagatose-bisphosphate aldolase activity
D	0016829	molecular_function	lyase activity
D	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
D	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
D	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
D	2001059	biological_process	D-tagatose 6-phosphate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	binding site for residue P6F A 3001

Chain	Residue
A	ASP27
A	SER249
A	ALA250
A	LEU275
A	CYS276
A	GLY277
A	ARG278
A	CL3003
A	HOH3108
A	HOH3111
A	HOH3115
A	GLN28
A	HOH3147
A	HOH3236
A	HOH3272
A	HOH3274
A	HOH3310
A	ARG29
A	GLY30
A	ALA31
A	LEU68
A	THR94
A	LEU127
A	GLU163

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CL A 3003

Chain	Residue
A	ARG29
A	GLY30
A	ALA31
A	THR94
A	P6F3001

---

site_id	AC3
Number of Residues	7
Details	binding site for residue CA A 3004

Chain	Residue
A	HOH3277
A	HOH3298
A	HOH3341
A	HOH3454
B	HOH646
B	HOH834
B	HOH853

---

site_id	AC4
Number of Residues	5
Details	binding site for residue CA A 3005

Chain	Residue
A	GLU238
A	THR241
A	HOH3263
B	GLU83
B	GLU84

---

site_id	AC5
Number of Residues	7
Details	binding site for residue CA B 402

Chain	Residue
A	HOH3296
A	HOH3465
A	HOH3494
B	HOH635
B	HOH668
B	HOH686
B	HOH833

---

site_id	AC6
Number of Residues	5
Details	binding site for residue CA B 403

Chain	Residue
A	GLU83
A	GLU84
B	GLU238
B	THR241
B	HOH651

---

site_id	AC7
Number of Residues	4
Details	binding site for residue CA C 401

Chain	Residue
C	ASP259
D	ASP259
D	HOH465
D	HOH585

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