5F49

Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample in complex with malonyl-coenzyme A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	binding site for residue COA A 201

Chain	Residue
A	LEU92
A	LYS105
A	ASP131
A	TYR133
A	ASP136
A	PHE137
A	SER140
A	MG204
A	HOH301
A	HOH315
A	HOH352
A	ALA93
A	HOH371
A	HOH379
B	GLU18
B	HOH380
A	VAL94
A	GLN99
A	ARG100
A	GLN101
A	GLY102
A	ILE103
A	GLY104

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 202

Chain	Residue
A	GLU18
A	ASN53
A	ASN55
A	HOH389
A	HOH395
A	HOH398

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG A 203

Chain	Residue
A	ASN39
A	HOH378
A	HOH424
C	HOH314
D	HOH304
D	HOH316

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MG A 204

Chain	Residue
A	COA201
A	HOH379
B	GLU18
B	ASN53
B	HOH380

---

site_id	AC5
Number of Residues	28
Details	binding site for residue MLC B 201

Chain	Residue
A	ASN19
A	PRO22
B	VAL34
B	PHE35
B	ASP91
B	LEU92
B	ALA93
B	VAL94
B	GLN99
B	ARG100
B	GLN101
B	GLY102
B	ILE103
B	GLY104
B	LYS105
B	ASP128
B	TYR133
B	ASP136
B	PHE137
B	SER140
B	HOH310
B	HOH316
B	HOH320
B	HOH349
B	HOH371
B	HOH377
B	HOH379
B	HOH384

---

site_id	AC6
Number of Residues	5
Details	binding site for residue MG B 202

Chain	Residue
A	HOH350
B	GLU14
B	ASP20
B	HOH338
B	HOH369

---

site_id	AC7
Number of Residues	6
Details	binding site for residue MG B 203

Chain	Residue
A	ASP44
A	HOH304
A	HOH333
B	GLU83
B	HOH333
C	PHE40

---

site_id	AC8
Number of Residues	26
Details	binding site for residue MLC C 201

Chain	Residue
C	HOH306
C	HOH311
C	HOH339
C	HOH358
D	GLU18
D	HOH305
C	VAL34
C	PHE35
C	TYR90
C	ASP91
C	LEU92
C	ALA93
C	VAL94
C	GLN99
C	ARG100
C	GLN101
C	GLY102
C	ILE103
C	GLY104
C	LYS105
C	TYR133
C	ASP136
C	PHE137
C	TYR138
C	SER140
C	MG202

---

site_id	AC9
Number of Residues	6
Details	binding site for residue MG C 202

Chain	Residue
C	MLC201
C	HOH306
C	HOH311
D	GLU18
D	ASN53
D	HOH305

---

site_id	AD1
Number of Residues	17
Details	binding site for residue MLC D 201

Chain	Residue
D	VAL34
D	PHE35
D	TYR90
D	ASP91
D	LEU92
D	VAL94
D	GLN99
D	ARG100
D	GLN101
D	GLY102
D	ILE103
D	GLY104
D	LYS105
D	TYR133
D	PHE137
D	TYR138
D	SER140

---

site_id	AD2
Number of Residues	5
Details	binding site for residue MG D 202

Chain	Residue
D	GLU14
D	ASP20
D	HOH336
D	HOH338
D	HOH345

---

site_id	AD3
Number of Residues	6
Details	binding site for residue MG D 203

Chain	Residue
A	PHE40
C	ASP44
C	HOH303
C	HOH325
D	GLU83
D	HOH307

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