5F3W
Structure of the ATPrS-Mre11/Rad50-DNA complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000403 | molecular_function | Y-form DNA binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0004529 | molecular_function | DNA exonuclease activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006302 | biological_process | double-strand break repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0045027 | molecular_function | DNA end binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0006302 | biological_process | double-strand break repair |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0000403 | molecular_function | Y-form DNA binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004518 | molecular_function | nuclease activity |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0004527 | molecular_function | exonuclease activity |
| C | 0004529 | molecular_function | DNA exonuclease activity |
| C | 0006281 | biological_process | DNA repair |
| C | 0006302 | biological_process | double-strand break repair |
| C | 0006974 | biological_process | DNA damage response |
| C | 0008408 | molecular_function | 3'-5' exonuclease activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0030145 | molecular_function | manganese ion binding |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0045027 | molecular_function | DNA end binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0006302 | biological_process | double-strand break repair |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 401 |
| Chain | Residue |
| A | ASP8 |
| A | HIS10 |
| A | ASP49 |
| A | HIS188 |
| A | MG402 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | MG401 |
| A | ASP49 |
| A | ASN84 |
| A | HIS158 |
| A | HIS186 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | binding site for residue AGS B 1101 |
| Chain | Residue |
| B | LYS14 |
| B | SER15 |
| B | GLY35 |
| B | SER36 |
| B | GLY37 |
| B | LYS38 |
| B | SER39 |
| B | SER40 |
| B | THR60 |
| B | ILE62 |
| B | THR63 |
| B | LYS64 |
| B | GLN134 |
| B | ASP946 |
| B | GLU947 |
| B | LYS994 |
| D | TYR890 |
| D | LEU910 |
| D | ASN914 |
| D | SER916 |
| D | GLY917 |
| D | GLU919 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 401 |
| Chain | Residue |
| C | ASP49 |
| C | ASN84 |
| C | HIS158 |
| C | HIS186 |
| C | MG402 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 402 |
| Chain | Residue |
| C | ASP8 |
| C | HIS10 |
| C | ASP49 |
| C | HIS188 |
| C | MG401 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | binding site for residue AGS D 1101 |
| Chain | Residue |
| B | TYR890 |
| B | LEU910 |
| B | ASN914 |
| B | SER916 |
| B | GLU919 |
| D | LYS14 |
| D | SER15 |
| D | GLU33 |
| D | GLY35 |
| D | SER36 |
| D | GLY37 |
| D | LYS38 |
| D | SER39 |
| D | SER40 |
| D | THR60 |
| D | ILE62 |
| D | THR63 |
| D | LYS64 |
| D | GLN134 |
| D | GLU947 |
| D | LYS994 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00449, ECO:0007744|PDB:3AUY |
| Chain | Residue | Details |
| B | LYS14 | |
| D | LYS14 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3AUX, ECO:0007744|PDB:3AUY |
| Chain | Residue | Details |
| B | GLY35 | |
| C | ASP49 | |
| C | ASN84 | |
| C | HIS158 | |
| C | HIS186 | |
| C | HIS188 | |
| B | ILE62 | |
| D | GLY35 | |
| D | ILE62 | |
| A | HIS158 | |
| A | HIS186 | |
| A | HIS188 | |
| C | ASP8 | |
| C | HIS10 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00449 |
| Chain | Residue | Details |
| B | GLN134 | |
| D | GLN134 |
