5F2Q
C-type lectin from Bothrops jararacussu
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0030308 | biological_process | negative regulation of cell growth |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0030308 | biological_process | negative regulation of cell growth |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0030246 | molecular_function | carbohydrate binding |
| C | 0030308 | biological_process | negative regulation of cell growth |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0030246 | molecular_function | carbohydrate binding |
| D | 0030308 | biological_process | negative regulation of cell growth |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0005576 | cellular_component | extracellular region |
| E | 0030246 | molecular_function | carbohydrate binding |
| E | 0030308 | biological_process | negative regulation of cell growth |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0005576 | cellular_component | extracellular region |
| F | 0030246 | molecular_function | carbohydrate binding |
| F | 0030308 | biological_process | negative regulation of cell growth |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0005576 | cellular_component | extracellular region |
| G | 0030246 | molecular_function | carbohydrate binding |
| G | 0030308 | biological_process | negative regulation of cell growth |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0005576 | cellular_component | extracellular region |
| H | 0030246 | molecular_function | carbohydrate binding |
| H | 0030308 | biological_process | negative regulation of cell growth |
| H | 0046872 | molecular_function | metal ion binding |
| I | 0005576 | cellular_component | extracellular region |
| I | 0030246 | molecular_function | carbohydrate binding |
| I | 0030308 | biological_process | negative regulation of cell growth |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0005576 | cellular_component | extracellular region |
| J | 0030246 | molecular_function | carbohydrate binding |
| J | 0030308 | biological_process | negative regulation of cell growth |
| J | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 201 |
| Chain | Residue |
| A | GLN96 |
| A | ASP98 |
| A | GLU104 |
| A | ASN119 |
| A | ASP120 |
| A | HOH301 |
| A | HOH302 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 202 |
| Chain | Residue |
| A | HIS44 |
| A | GLN132 |
| A | TYR15 |
| A | SER42 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 201 |
| Chain | Residue |
| B | GLN96 |
| B | ASP98 |
| B | GLU104 |
| B | ASN119 |
| B | ASP120 |
| B | HOH301 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 202 |
| Chain | Residue |
| B | LEU13 |
| B | TYR15 |
| B | SER42 |
| B | HIS44 |
| B | GLN132 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 201 |
| Chain | Residue |
| C | GLN96 |
| C | ASP98 |
| C | GLU104 |
| C | ASN119 |
| C | ASP120 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue NA C 202 |
| Chain | Residue |
| C | TYR15 |
| C | SER42 |
| C | HIS44 |
| C | GLN132 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 201 |
| Chain | Residue |
| D | GLN96 |
| D | ASP98 |
| D | GLU104 |
| D | ASN119 |
| D | ASP120 |
| D | HOH301 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue NA D 202 |
| Chain | Residue |
| D | LEU13 |
| D | TYR15 |
| D | SER42 |
| D | GLN132 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue CA E 201 |
| Chain | Residue |
| E | GLN96 |
| E | ASP98 |
| E | GLU104 |
| E | ASN119 |
| E | ASP120 |
| E | HOH305 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue NA E 202 |
| Chain | Residue |
| E | LEU13 |
| E | TYR15 |
| E | SER42 |
| E | GLN132 |
| E | HOH301 |
| E | HOH309 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CA F 201 |
| Chain | Residue |
| F | GLN96 |
| F | ASP98 |
| F | GLU104 |
| F | ASN119 |
| F | ASP120 |
| F | HOH302 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue NA F 202 |
| Chain | Residue |
| F | TYR15 |
| F | SER42 |
| F | GLN132 |
| F | HOH301 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue CA G 201 |
| Chain | Residue |
| G | GLN96 |
| G | ASP98 |
| G | GLU104 |
| G | ASN119 |
| G | ASP120 |
| G | HOH302 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue NA G 202 |
| Chain | Residue |
| G | TYR15 |
| G | SER42 |
| G | GLN132 |
| G | HOH301 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue CA H 201 |
| Chain | Residue |
| H | GLN96 |
| H | ASP98 |
| H | GLU104 |
| H | ASN119 |
| H | ASP120 |
| H | HOH301 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue NA H 202 |
| Chain | Residue |
| H | TYR15 |
| H | SER42 |
| H | HIS44 |
| H | GLN132 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue CA I 201 |
| Chain | Residue |
| I | GLN96 |
| I | ASP98 |
| I | GLU104 |
| I | ASN119 |
| I | ASP120 |
| I | HOH301 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue NA I 202 |
| Chain | Residue |
| I | LEU13 |
| I | TYR15 |
| I | SER42 |
| I | HIS44 |
| I | GLN132 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue CA J 201 |
| Chain | Residue |
| J | HOH301 |
| J | HOH302 |
| J | GLN96 |
| J | ASP98 |
| J | GLU104 |
| J | ASN119 |
| J | ASP120 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue NA J 202 |
| Chain | Residue |
| J | LEU13 |
| J | TYR15 |
| J | SER42 |
| J | HIS44 |
| J | GLN132 |
Functional Information from PROSITE/UniProt
| site_id | PS00615 |
| Number of Residues | 26 |
| Details | C_TYPE_LECTIN_1 C-type lectin domain signature. CVelvsntgyrl..WNDQVCeskna.FLC |
| Chain | Residue | Details |
| A | CYS106-CYS131 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1220 |
| Details | Domain: {"description":"C-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00040","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Motif: {"description":"Galactose-binding","evidences":[{"source":"UniProtKB","id":"P21963","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 50 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28003128","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5F2Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Site: {"description":"Binds aminoglycoside antibiotics (subunit E')","evidences":[{"source":"PubMed","id":"28003128","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Site: {"description":"Binds aminoglycoside antibiotics (subunit A and E')","evidences":[{"source":"PubMed","id":"28003128","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | Site: {"description":"Binds aminoglycoside antibiotics (subunit A)","evidences":[{"source":"PubMed","id":"28003128","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
