5F2M
Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with competitive inhibitor hexitol-1,6-bisphosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| A | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| A | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| A | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| A | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| B | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| B | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| B | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| B | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| B | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| C | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| C | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| C | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| C | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| C | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| D | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| D | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| D | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| D | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| D | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue M2P A 3001 |
| Chain | Residue |
| A | ASP27 |
| A | ALA250 |
| A | LEU275 |
| A | CYS276 |
| A | GLY277 |
| A | ARG278 |
| A | HOH3117 |
| A | HOH3137 |
| A | HOH3140 |
| A | HOH3173 |
| A | HOH3203 |
| A | GLN28 |
| A | HOH3305 |
| A | ARG29 |
| A | GLY30 |
| A | ALA31 |
| A | THR94 |
| A | GLU163 |
| A | LYS205 |
| A | SER249 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 3002 |
| Chain | Residue |
| A | HOH3279 |
| A | HOH3323 |
| A | HOH3324 |
| A | HOH3418 |
| B | HOH735 |
| B | HOH921 |
| B | HOH929 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 3003 |
| Chain | Residue |
| A | GLU238 |
| A | THR241 |
| A | HOH3123 |
| A | HOH3272 |
| B | GLU83 |
| B | GLU84 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 3004 |
| Chain | Residue |
| A | HOH3350 |
| D | HOH783 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 401 |
| Chain | Residue |
| A | GLU83 |
| A | GLU84 |
| B | GLU238 |
| B | THR241 |
| B | HOH670 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 402 |
| Chain | Residue |
| A | HOH3312 |
| A | HOH3449 |
| A | HOH3459 |
| B | HOH736 |
| B | HOH741 |
| B | HOH803 |
| B | HOH893 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 403 |
| Chain | Residue |
| B | HOH742 |
| B | HOH875 |
| B | HOH877 |
| B | HOH992 |
| C | HOH729 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 404 |
| Chain | Residue |
| B | ALA37 |
| B | GLN40 |
| B | HOH589 |
| B | HOH780 |
| B | HOH881 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 401 |
| Chain | Residue |
| C | GLU84 |
| C | HOH502 |
| C | HOH546 |
| C | HOH584 |
| C | HOH591 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 401 |
| Chain | Residue |
| C | ASP259 |
| C | HOH635 |
| C | HOH650 |
| D | ASP259 |
| D | HOH597 |
| D | HOH695 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue CA D 402 |
| Chain | Residue |
| D | HOH683 |
| D | HOH715 |
| D | HOH735 |
| D | HOH785 |
