5F2M

Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with competitive inhibitor hexitol-1,6-bisphosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005988	biological_process	lactose metabolic process
A	0009024	molecular_function	tagatose-6-phosphate kinase activity
A	0009025	molecular_function	tagatose-bisphosphate aldolase activity
A	0016829	molecular_function	lyase activity
A	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
A	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
A	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
A	2001059	biological_process	D-tagatose 6-phosphate catabolic process
B	0003824	molecular_function	catalytic activity
B	0005988	biological_process	lactose metabolic process
B	0009024	molecular_function	tagatose-6-phosphate kinase activity
B	0009025	molecular_function	tagatose-bisphosphate aldolase activity
B	0016829	molecular_function	lyase activity
B	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
B	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
B	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
B	2001059	biological_process	D-tagatose 6-phosphate catabolic process
C	0003824	molecular_function	catalytic activity
C	0005988	biological_process	lactose metabolic process
C	0009024	molecular_function	tagatose-6-phosphate kinase activity
C	0009025	molecular_function	tagatose-bisphosphate aldolase activity
C	0016829	molecular_function	lyase activity
C	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
C	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
C	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
C	2001059	biological_process	D-tagatose 6-phosphate catabolic process
D	0003824	molecular_function	catalytic activity
D	0005988	biological_process	lactose metabolic process
D	0009024	molecular_function	tagatose-6-phosphate kinase activity
D	0009025	molecular_function	tagatose-bisphosphate aldolase activity
D	0016829	molecular_function	lyase activity
D	0019512	biological_process	lactose catabolic process via tagatose-6-phosphate
D	0061595	molecular_function	6-deoxy-6-sulfofructose-1-phosphate aldolase activity
D	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
D	2001059	biological_process	D-tagatose 6-phosphate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue M2P A 3001

Chain	Residue
A	ASP27
A	ALA250
A	LEU275
A	CYS276
A	GLY277
A	ARG278
A	HOH3117
A	HOH3137
A	HOH3140
A	HOH3173
A	HOH3203
A	GLN28
A	HOH3305
A	ARG29
A	GLY30
A	ALA31
A	THR94
A	GLU163
A	LYS205
A	SER249

---

site_id	AC2
Number of Residues	7
Details	binding site for residue CA A 3002

Chain	Residue
A	HOH3279
A	HOH3323
A	HOH3324
A	HOH3418
B	HOH735
B	HOH921
B	HOH929

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CA A 3003

Chain	Residue
A	GLU238
A	THR241
A	HOH3123
A	HOH3272
B	GLU83
B	GLU84

---

site_id	AC4
Number of Residues	2
Details	binding site for residue CA A 3004

Chain	Residue
A	HOH3350
D	HOH783

---

site_id	AC5
Number of Residues	5
Details	binding site for residue CA B 401

Chain	Residue
A	GLU83
A	GLU84
B	GLU238
B	THR241
B	HOH670

---

site_id	AC6
Number of Residues	7
Details	binding site for residue CA B 402

Chain	Residue
A	HOH3312
A	HOH3449
A	HOH3459
B	HOH736
B	HOH741
B	HOH803
B	HOH893

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CA B 403

Chain	Residue
B	HOH742
B	HOH875
B	HOH877
B	HOH992
C	HOH729

---

site_id	AC8
Number of Residues	5
Details	binding site for residue CA B 404

Chain	Residue
B	ALA37
B	GLN40
B	HOH589
B	HOH780
B	HOH881

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CA C 401

Chain	Residue
C	GLU84
C	HOH502
C	HOH546
C	HOH584
C	HOH591

---

site_id	AD1
Number of Residues	6
Details	binding site for residue CA D 401

Chain	Residue
C	ASP259
C	HOH635
C	HOH650
D	ASP259
D	HOH597
D	HOH695

---

site_id	AD2
Number of Residues	4
Details	binding site for residue CA D 402

Chain	Residue
D	HOH683
D	HOH715
D	HOH735
D	HOH785

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