5F2I
Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes Glu163Gln mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005988 | biological_process | lactose metabolic process |
| A | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| A | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| A | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| A | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| A | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| B | 0005988 | biological_process | lactose metabolic process |
| B | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| B | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| B | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| B | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| B | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| C | 0005988 | biological_process | lactose metabolic process |
| C | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| C | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| C | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| C | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| C | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| D | 0005988 | biological_process | lactose metabolic process |
| D | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| D | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| D | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| D | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| D | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | HOH572 |
| A | HOH677 |
| A | HOH695 |
| A | HOH788 |
| A | HOH825 |
| D | HOH789 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| B | GLU83 |
| B | GLU84 |
| A | GLU238 |
| A | THR241 |
| A | HOH644 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ALA37 |
| A | GLN40 |
| A | HOH571 |
| D | HOH501 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue ACT A 404 |
| Chain | Residue |
| A | THR3 |
| A | LYS8 |
| A | GLY200 |
| A | ASP202 |
| A | HOH501 |
| A | HOH599 |
| A | HOH675 |
| A | HOH691 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 401 |
| Chain | Residue |
| A | HOH537 |
| A | HOH586 |
| A | HOH768 |
| B | PRO62 |
| B | HOH797 |
| B | HOH806 |
| B | HOH827 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 402 |
| Chain | Residue |
| B | ALA37 |
| B | GLN40 |
| B | HOH535 |
| B | HOH689 |
| B | HOH730 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 403 |
| Chain | Residue |
| A | GLU83 |
| A | GLU84 |
| A | HOH722 |
| B | GLU238 |
| B | THR241 |
| B | HOH510 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 404 |
| Chain | Residue |
| A | HOH629 |
| B | HOH598 |
| B | HOH643 |
| B | HOH677 |
| B | HOH695 |
| B | HOH793 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 405 |
| Chain | Residue |
| B | LYS317 |
| B | THR318 |
| B | ALA319 |
| B | GOL406 |
| B | HOH540 |
| B | HOH565 |
| B | HOH570 |
| B | HOH644 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 406 |
| Chain | Residue |
| A | LYS143 |
| A | LYS196 |
| B | ASP18 |
| B | ASP316 |
| B | ALA319 |
| B | PRO321 |
| B | GOL405 |
| B | HOH565 |
| B | HOH684 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 401 |
| Chain | Residue |
| C | ASP259 |
| C | HOH578 |
| C | HOH624 |
| D | ASP259 |
| D | HOH591 |
| D | HOH681 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 402 |
| Chain | Residue |
| C | GLU13 |
| C | SER16 |
| C | HOH527 |
| C | HOH636 |
| C | HOH656 |
| C | HOH677 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 403 |
| Chain | Residue |
| C | VAL20 |
| C | ASP316 |
| C | HOH596 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue CA D 401 |
| Chain | Residue |
| D | GLU13 |
| D | SER16 |
| D | HOH550 |
| D | HOH649 |
| D | HOH697 |
| D | HOH728 |
| D | HOH743 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 402 |
| Chain | Residue |
| D | GLU238 |
| D | THR241 |
| D | LYS325 |
| D | HOH609 |
| D | HOH630 |
| D | HOH713 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue GOL D 403 |
| Chain | Residue |
| D | ARG79 |
| D | GLU83 |
