Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue 5ST A 301 |
Chain | Residue |
A | ARG39 |
A | GLY193 |
A | ASP194 |
A | SER195 |
A | THR213 |
A | GLY218 |
A | HOH472 |
A | HOH502 |
A | HOH510 |
A | HIS40 |
A | LEU41 |
A | HIS57 |
A | ILE151 |
A | ASP189 |
A | ALA190 |
A | CYS191 |
A | LYS192 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue SO4 A 302 |
Chain | Residue |
A | ARG170 |
A | ARG170 |
A | ARG184 |
A | ARG184 |
site_id | AC3 |
Number of Residues | 10 |
Details | binding site for residue SO4 A 303 |
Chain | Residue |
A | VAL23 |
A | ARG24 |
A | GLY25 |
A | GLU26 |
A | TRP27 |
A | ILE70 |
A | LEU71 |
A | LEU155 |
A | HOH412 |
A | HOH415 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue EDO A 304 |
Chain | Residue |
A | ASN49 |
A | THR111 |
A | VAL112 |
A | GLY113 |
A | TYR114 |
site_id | AC5 |
Number of Residues | 6 |
Details | binding site for residue EDO A 305 |
Chain | Residue |
A | ARG24 |
A | SER99 |
A | GLY173 |
A | LYS175 |
A | HOH491 |
A | HOH496 |
site_id | AC6 |
Number of Residues | 4 |
Details | binding site for residue EDO A 306 |
Chain | Residue |
A | GLU98 |
A | GLY216 |
A | GLU217 |
A | HOH401 |
site_id | AC7 |
Number of Residues | 1 |
Details | binding site for residue EDO A 307 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue EDO A 308 |
Chain | Residue |
A | SER99 |
A | GLY100 |
A | TYR101 |
A | THR177 |
A | LYS179 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
A | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAckGDSGGPLS |
Chain | Residue | Details |
A | ASP189-SER200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS169 | |
Chain | Residue | Details |
A | ASN72 | |
Chain | Residue | Details |
A | GLY113 | |