5EWW
Crystal structure of the human BRPF1 bromodomain in complex with SEED21
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue 5SK A 801 |
| Chain | Residue |
| A | ILE652 |
| A | VAL657 |
| A | PRO658 |
| A | TYR707 |
| A | ASN708 |
| A | PHE714 |
| A | HOH920 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 A 802 |
| Chain | Residue |
| A | LYS706 |
| A | TYR715 |
| A | VAL719 |
| A | ARG722 |
| A | HOH934 |
| A | SER702 |
| A | LEU705 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY |
| Chain | Residue | Details |
| A | GLY650-TYR707 |
