5EUL

Structure of the SecA-SecY complex with a translocating polypeptide substrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0006605	biological_process	protein targeting
A	0006886	biological_process	intracellular protein transport
A	0016020	cellular_component	membrane
A	0017038	biological_process	protein import
E	0005886	cellular_component	plasma membrane
E	0006605	biological_process	protein targeting
E	0006886	biological_process	intracellular protein transport
E	0008320	molecular_function	protein transmembrane transporter activity
E	0009306	biological_process	protein secretion
E	0015031	biological_process	protein transport
E	0016020	cellular_component	membrane
E	0043952	biological_process	protein transport by the Sec complex
E	0065002	biological_process	intracellular protein transmembrane transport
Y	0005886	cellular_component	plasma membrane
Y	0006605	biological_process	protein targeting
Y	0015031	biological_process	protein transport
Y	0016020	cellular_component	membrane
Y	0043952	biological_process	protein transport by the Sec complex
Y	0065002	biological_process	intracellular protein transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue MG A 1001

Chain	Residue
A	ADP1003

---

site_id	AC2
Number of Residues	4
Details	binding site for residue BEF A 1002

Chain	Residue
A	THR102
A	GLY103
A	ASP492
A	ADP1003

---

site_id	AC3
Number of Residues	14
Details	binding site for residue ADP A 1003

Chain	Residue
A	GLY103
A	GLY105
A	LYS106
A	THR107
A	LEU108
A	ASP492
A	ARG528
A	GLN529
A	MG1001
A	BEF1002
A	MET79
A	PHE80
A	PHE82
A	GLN85

---

site_id	AC4
Number of Residues	6
Details	binding site for residue TBR A 1004

Chain	Residue
A	ASP591
A	GLN595
A	GLN598
A	TYR599
Y	GLU103
Y	ARG106

---

site_id	AC5
Number of Residues	4
Details	binding site for residue TBR A 1005

Chain	Residue
A	GLU798
A	MET801
A	GLU802
Y	PRO263

---

site_id	AC6
Number of Residues	8
Details	binding site for residue TBR A 1006

Chain	Residue
A	THR251
A	ASP253
A	THR256
A	VAL298
A	ALA299
A	MET300
A	GLU544
A	ARG547

---

site_id	AC7
Number of Residues	5
Details	binding site for residue TBR A 1007

Chain	Residue
A	LYS302
A	ASP303
A	GLU443
A	LYS447
A	LYS462

---

site_id	AC8
Number of Residues	3
Details	binding site for residue TBR A 1008

Chain	Residue
A	HIS43
A	GLU47
A	GLU50

---

site_id	AC9
Number of Residues	5
Details	binding site for residue TBR A 1009

Chain	Residue
A	THR120
A	HIS202
A	ASP276
A	GLU365
A	LYS366

---

site_id	AD1
Number of Residues	5
Details	binding site for residue TBR A 1010

Chain	Residue
A	GLU625
A	GLU628
A	ASN629
A	MET689
A	ILE693

---

site_id	AD2
Number of Residues	4
Details	binding site for residue TBR A 1011

Chain	Residue
A	LYS723
A	ASP726
A	HIS809
A	SER813

---

site_id	AD3
Number of Residues	6
Details	binding site for residue TBR A 1012

Chain	Residue
A	ASP773
A	GLU778
A	GLU780
Y	SER289
Y	ARG301
Y	ARG302

---

site_id	AD4
Number of Residues	7
Details	binding site for residue TBR A 1013

Chain	Residue
A	LYS229
A	LYS232
A	TYR234
A	ALA285
A	HIS288
A	HIS289
A	GLU348

---

site_id	AD5
Number of Residues	6
Details	binding site for residue TBR A 1014

Chain	Residue
A	GLU309
A	ASP310
A	LYS325
A	LYS462
A	HIS464
A	GLU465

---

site_id	AD6
Number of Residues	4
Details	binding site for residue TBR A 1015

Chain	Residue
A	GLU443
A	SER446
A	LYS450
A	VAL458

---

site_id	AD7
Number of Residues	4
Details	binding site for residue TBR A 1016

Chain	Residue
A	GLU34
A	GLU71
A	ARG74
A	ARG75

---

site_id	AD8
Number of Residues	7
Details	binding site for residue TBR A 1017

Chain	Residue
A	THR376
A	GLU379
A	LYS583
A	GLU586
A	PHE590
Y	MET104
Y	ARG107

---

site_id	AD9
Number of Residues	4
Details	binding site for residue TBR A 1018

Chain	Residue
A	ARG14
A	GLU378
A	GLU379
A	GLN388

---

site_id	AE1
Number of Residues	3
Details	binding site for residue TBR Y 501

Chain	Residue
Y	PRO242
A	GLU50
A	GLU53

---

site_id	AE2
Number of Residues	2
Details	binding site for residue TBR Y 502

Chain	Residue
A	PHE804
Y	GLU417

---

site_id	AE3
Number of Residues	3
Details	binding site for residue TBR Y 503

Chain	Residue
A	ARG553
Y	LYS94
Y	GLU97

---

Functional Information from PROSITE/UniProt

site_id	PS00755
Number of Residues	20
Details	SECY_1 Protein secY signature 1. SIFaMGVmPYItASIIVQLL

Chain	Residue	Details
Y	SER68-LEU87

---

site_id	PS00756
Number of Residues	18
Details	SECY_2 Protein secY signature 2. WLgEqITak.GVGNGiSII

Chain	Residue	Details
Y	TRP165-ILE182

---

site_id	PS01067
Number of Residues	29
Details	SECE_SEC61G Protein secE/sec61-gamma signature. FfKEvVreLkKvsWPnrkElvnytAVVLA

Chain	Residue	Details
E	PHE7-ALA35

---

site_id	PS01312
Number of Residues	16
Details	SECA SecA family signature. VtIATNMAGRGtDIkL

Chain	Residue	Details
A	VAL480-LEU495

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15256599","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19850053","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TF2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3JV2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01382","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12242434","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15256599","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16989859","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19850053","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1M74","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1TF2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3JV2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01382","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12242434","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15256599","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16989859","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1M74","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1TF2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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