Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
A | 0003824 | molecular_function | catalytic activity |
A | 0004737 | molecular_function | pyruvate decarboxylase activity |
A | 0005829 | cellular_component | cytosol |
A | 0016831 | molecular_function | carboxy-lyase activity |
A | 0019752 | biological_process | carboxylic acid metabolic process |
A | 0030976 | molecular_function | thiamine pyrophosphate binding |
A | 0046872 | molecular_function | metal ion binding |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
B | 0003824 | molecular_function | catalytic activity |
B | 0004737 | molecular_function | pyruvate decarboxylase activity |
B | 0005829 | cellular_component | cytosol |
B | 0016831 | molecular_function | carboxy-lyase activity |
B | 0019752 | biological_process | carboxylic acid metabolic process |
B | 0030976 | molecular_function | thiamine pyrophosphate binding |
B | 0046872 | molecular_function | metal ion binding |
C | 0000287 | molecular_function | magnesium ion binding |
C | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
C | 0003824 | molecular_function | catalytic activity |
C | 0004737 | molecular_function | pyruvate decarboxylase activity |
C | 0005829 | cellular_component | cytosol |
C | 0016831 | molecular_function | carboxy-lyase activity |
C | 0019752 | biological_process | carboxylic acid metabolic process |
C | 0030976 | molecular_function | thiamine pyrophosphate binding |
C | 0046872 | molecular_function | metal ion binding |
D | 0000287 | molecular_function | magnesium ion binding |
D | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
D | 0003824 | molecular_function | catalytic activity |
D | 0004737 | molecular_function | pyruvate decarboxylase activity |
D | 0005829 | cellular_component | cytosol |
D | 0016831 | molecular_function | carboxy-lyase activity |
D | 0019752 | biological_process | carboxylic acid metabolic process |
D | 0030976 | molecular_function | thiamine pyrophosphate binding |
D | 0046872 | molecular_function | metal ion binding |
E | 0000287 | molecular_function | magnesium ion binding |
E | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
E | 0003824 | molecular_function | catalytic activity |
E | 0004737 | molecular_function | pyruvate decarboxylase activity |
E | 0005829 | cellular_component | cytosol |
E | 0016831 | molecular_function | carboxy-lyase activity |
E | 0019752 | biological_process | carboxylic acid metabolic process |
E | 0030976 | molecular_function | thiamine pyrophosphate binding |
E | 0046872 | molecular_function | metal ion binding |
F | 0000287 | molecular_function | magnesium ion binding |
F | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
F | 0003824 | molecular_function | catalytic activity |
F | 0004737 | molecular_function | pyruvate decarboxylase activity |
F | 0005829 | cellular_component | cytosol |
F | 0016831 | molecular_function | carboxy-lyase activity |
F | 0019752 | biological_process | carboxylic acid metabolic process |
F | 0030976 | molecular_function | thiamine pyrophosphate binding |
F | 0046872 | molecular_function | metal ion binding |
G | 0000287 | molecular_function | magnesium ion binding |
G | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
G | 0003824 | molecular_function | catalytic activity |
G | 0004737 | molecular_function | pyruvate decarboxylase activity |
G | 0005829 | cellular_component | cytosol |
G | 0016831 | molecular_function | carboxy-lyase activity |
G | 0019752 | biological_process | carboxylic acid metabolic process |
G | 0030976 | molecular_function | thiamine pyrophosphate binding |
G | 0046872 | molecular_function | metal ion binding |
H | 0000287 | molecular_function | magnesium ion binding |
H | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
H | 0003824 | molecular_function | catalytic activity |
H | 0004737 | molecular_function | pyruvate decarboxylase activity |
H | 0005829 | cellular_component | cytosol |
H | 0016831 | molecular_function | carboxy-lyase activity |
H | 0019752 | biological_process | carboxylic acid metabolic process |
H | 0030976 | molecular_function | thiamine pyrophosphate binding |
H | 0046872 | molecular_function | metal ion binding |
I | 0000287 | molecular_function | magnesium ion binding |
I | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
I | 0003824 | molecular_function | catalytic activity |
I | 0004737 | molecular_function | pyruvate decarboxylase activity |
I | 0005829 | cellular_component | cytosol |
I | 0016831 | molecular_function | carboxy-lyase activity |
I | 0019752 | biological_process | carboxylic acid metabolic process |
I | 0030976 | molecular_function | thiamine pyrophosphate binding |
I | 0046872 | molecular_function | metal ion binding |
J | 0000287 | molecular_function | magnesium ion binding |
J | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
J | 0003824 | molecular_function | catalytic activity |
J | 0004737 | molecular_function | pyruvate decarboxylase activity |
J | 0005829 | cellular_component | cytosol |
J | 0016831 | molecular_function | carboxy-lyase activity |
J | 0019752 | biological_process | carboxylic acid metabolic process |
J | 0030976 | molecular_function | thiamine pyrophosphate binding |
J | 0046872 | molecular_function | metal ion binding |
K | 0000287 | molecular_function | magnesium ion binding |
K | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
K | 0003824 | molecular_function | catalytic activity |
K | 0004737 | molecular_function | pyruvate decarboxylase activity |
K | 0005829 | cellular_component | cytosol |
K | 0016831 | molecular_function | carboxy-lyase activity |
K | 0019752 | biological_process | carboxylic acid metabolic process |
K | 0030976 | molecular_function | thiamine pyrophosphate binding |
K | 0046872 | molecular_function | metal ion binding |
L | 0000287 | molecular_function | magnesium ion binding |
L | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
L | 0003824 | molecular_function | catalytic activity |
L | 0004737 | molecular_function | pyruvate decarboxylase activity |
L | 0005829 | cellular_component | cytosol |
L | 0016831 | molecular_function | carboxy-lyase activity |
L | 0019752 | biological_process | carboxylic acid metabolic process |
L | 0030976 | molecular_function | thiamine pyrophosphate binding |
L | 0046872 | molecular_function | metal ion binding |
M | 0000287 | molecular_function | magnesium ion binding |
M | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
M | 0003824 | molecular_function | catalytic activity |
M | 0004737 | molecular_function | pyruvate decarboxylase activity |
M | 0005829 | cellular_component | cytosol |
M | 0016831 | molecular_function | carboxy-lyase activity |
M | 0019752 | biological_process | carboxylic acid metabolic process |
M | 0030976 | molecular_function | thiamine pyrophosphate binding |
M | 0046872 | molecular_function | metal ion binding |
N | 0000287 | molecular_function | magnesium ion binding |
N | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
N | 0003824 | molecular_function | catalytic activity |
N | 0004737 | molecular_function | pyruvate decarboxylase activity |
N | 0005829 | cellular_component | cytosol |
N | 0016831 | molecular_function | carboxy-lyase activity |
N | 0019752 | biological_process | carboxylic acid metabolic process |
N | 0030976 | molecular_function | thiamine pyrophosphate binding |
N | 0046872 | molecular_function | metal ion binding |
O | 0000287 | molecular_function | magnesium ion binding |
O | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
O | 0003824 | molecular_function | catalytic activity |
O | 0004737 | molecular_function | pyruvate decarboxylase activity |
O | 0005829 | cellular_component | cytosol |
O | 0016831 | molecular_function | carboxy-lyase activity |
O | 0019752 | biological_process | carboxylic acid metabolic process |
O | 0030976 | molecular_function | thiamine pyrophosphate binding |
O | 0046872 | molecular_function | metal ion binding |
P | 0000287 | molecular_function | magnesium ion binding |
P | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
P | 0003824 | molecular_function | catalytic activity |
P | 0004737 | molecular_function | pyruvate decarboxylase activity |
P | 0005829 | cellular_component | cytosol |
P | 0016831 | molecular_function | carboxy-lyase activity |
P | 0019752 | biological_process | carboxylic acid metabolic process |
P | 0030976 | molecular_function | thiamine pyrophosphate binding |
P | 0046872 | molecular_function | metal ion binding |
Q | 0000287 | molecular_function | magnesium ion binding |
Q | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
Q | 0003824 | molecular_function | catalytic activity |
Q | 0004737 | molecular_function | pyruvate decarboxylase activity |
Q | 0005829 | cellular_component | cytosol |
Q | 0016831 | molecular_function | carboxy-lyase activity |
Q | 0019752 | biological_process | carboxylic acid metabolic process |
Q | 0030976 | molecular_function | thiamine pyrophosphate binding |
Q | 0046872 | molecular_function | metal ion binding |
R | 0000287 | molecular_function | magnesium ion binding |
R | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
R | 0003824 | molecular_function | catalytic activity |
R | 0004737 | molecular_function | pyruvate decarboxylase activity |
R | 0005829 | cellular_component | cytosol |
R | 0016831 | molecular_function | carboxy-lyase activity |
R | 0019752 | biological_process | carboxylic acid metabolic process |
R | 0030976 | molecular_function | thiamine pyrophosphate binding |
R | 0046872 | molecular_function | metal ion binding |
S | 0000287 | molecular_function | magnesium ion binding |
S | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
S | 0003824 | molecular_function | catalytic activity |
S | 0004737 | molecular_function | pyruvate decarboxylase activity |
S | 0005829 | cellular_component | cytosol |
S | 0016831 | molecular_function | carboxy-lyase activity |
S | 0019752 | biological_process | carboxylic acid metabolic process |
S | 0030976 | molecular_function | thiamine pyrophosphate binding |
S | 0046872 | molecular_function | metal ion binding |
T | 0000287 | molecular_function | magnesium ion binding |
T | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
T | 0003824 | molecular_function | catalytic activity |
T | 0004737 | molecular_function | pyruvate decarboxylase activity |
T | 0005829 | cellular_component | cytosol |
T | 0016831 | molecular_function | carboxy-lyase activity |
T | 0019752 | biological_process | carboxylic acid metabolic process |
T | 0030976 | molecular_function | thiamine pyrophosphate binding |
T | 0046872 | molecular_function | metal ion binding |
U | 0000287 | molecular_function | magnesium ion binding |
U | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
U | 0003824 | molecular_function | catalytic activity |
U | 0004737 | molecular_function | pyruvate decarboxylase activity |
U | 0005829 | cellular_component | cytosol |
U | 0016831 | molecular_function | carboxy-lyase activity |
U | 0019752 | biological_process | carboxylic acid metabolic process |
U | 0030976 | molecular_function | thiamine pyrophosphate binding |
U | 0046872 | molecular_function | metal ion binding |
V | 0000287 | molecular_function | magnesium ion binding |
V | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
V | 0003824 | molecular_function | catalytic activity |
V | 0004737 | molecular_function | pyruvate decarboxylase activity |
V | 0005829 | cellular_component | cytosol |
V | 0016831 | molecular_function | carboxy-lyase activity |
V | 0019752 | biological_process | carboxylic acid metabolic process |
V | 0030976 | molecular_function | thiamine pyrophosphate binding |
V | 0046872 | molecular_function | metal ion binding |
W | 0000287 | molecular_function | magnesium ion binding |
W | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
W | 0003824 | molecular_function | catalytic activity |
W | 0004737 | molecular_function | pyruvate decarboxylase activity |
W | 0005829 | cellular_component | cytosol |
W | 0016831 | molecular_function | carboxy-lyase activity |
W | 0019752 | biological_process | carboxylic acid metabolic process |
W | 0030976 | molecular_function | thiamine pyrophosphate binding |
W | 0046872 | molecular_function | metal ion binding |
X | 0000287 | molecular_function | magnesium ion binding |
X | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
X | 0003824 | molecular_function | catalytic activity |
X | 0004737 | molecular_function | pyruvate decarboxylase activity |
X | 0005829 | cellular_component | cytosol |
X | 0016831 | molecular_function | carboxy-lyase activity |
X | 0019752 | biological_process | carboxylic acid metabolic process |
X | 0030976 | molecular_function | thiamine pyrophosphate binding |
X | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue MG A 601 |
Chain | Residue |
A | ASP435 |
A | ASN462 |
A | GLY464 |
A | TPP602 |
A | HOH774 |
site_id | AC2 |
Number of Residues | 24 |
Details | binding site for residue TPP A 602 |
Chain | Residue |
A | ILE410 |
A | GLY434 |
A | ASP435 |
A | GLY436 |
A | SER437 |
A | ASN462 |
A | GLY464 |
A | TYR465 |
A | VAL466 |
A | ILE467 |
A | GLU468 |
A | MG601 |
A | HOH718 |
A | HOH743 |
A | HOH774 |
B | ALA24 |
B | GLY25 |
B | GLU49 |
B | VAL74 |
B | HIS113 |
A | GLY384 |
A | ASP385 |
A | GLY408 |
A | HIS409 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue EDO A 603 |
Chain | Residue |
A | SER217 |
A | ALA244 |
A | ASN287 |
A | MET405 |
A | GLN406 |
A | HOH729 |
A | HOH767 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue MG B 601 |
Chain | Residue |
B | ASP435 |
B | ASN462 |
B | GLY464 |
B | TPP602 |
B | HOH787 |
site_id | AC5 |
Number of Residues | 24 |
Details | binding site for residue TPP B 602 |
Chain | Residue |
A | ALA24 |
A | GLY25 |
A | GLU49 |
A | VAL74 |
A | HIS113 |
B | GLY384 |
B | ASP385 |
B | GLY408 |
B | HIS409 |
B | ILE410 |
B | GLY434 |
B | ASP435 |
B | GLY436 |
B | SER437 |
B | ASN462 |
B | GLY464 |
B | TYR465 |
B | VAL466 |
B | ILE467 |
B | GLU468 |
B | MG601 |
B | HOH729 |
B | HOH758 |
B | HOH787 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue MG C 601 |
Chain | Residue |
C | ASP435 |
C | ASN462 |
C | GLY464 |
C | TPP602 |
C | HOH781 |
site_id | AC7 |
Number of Residues | 23 |
Details | binding site for residue TPP C 602 |
Chain | Residue |
C | ASP385 |
C | GLY408 |
C | HIS409 |
C | ILE410 |
C | GLY434 |
C | ASP435 |
C | GLY436 |
C | SER437 |
C | ASN462 |
C | GLY464 |
C | TYR465 |
C | VAL466 |
C | ILE467 |
C | GLU468 |
C | MG601 |
C | HOH704 |
C | HOH741 |
C | HOH781 |
D | ALA24 |
D | GLY25 |
D | GLU49 |
D | VAL74 |
D | HIS113 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue MG D 601 |
Chain | Residue |
D | ASP435 |
D | ASN462 |
D | GLY464 |
D | TPP602 |
D | HOH743 |
site_id | AC9 |
Number of Residues | 24 |
Details | binding site for residue TPP D 602 |
Chain | Residue |
C | GLY25 |
C | GLU49 |
C | VAL74 |
C | HIS113 |
D | GLY384 |
D | ASP385 |
D | GLY408 |
D | HIS409 |
D | ILE410 |
D | GLY434 |
D | ASP435 |
D | GLY436 |
D | SER437 |
D | ASN462 |
D | GLY464 |
D | TYR465 |
D | VAL466 |
D | ILE467 |
D | GLU468 |
D | MG601 |
D | HOH716 |
D | HOH741 |
D | HOH743 |
C | ALA24 |
site_id | AD1 |
Number of Residues | 5 |
Details | binding site for residue MG E 601 |
Chain | Residue |
E | ASP435 |
E | ASN462 |
E | GLY464 |
E | TPP602 |
E | HOH728 |
site_id | AD2 |
Number of Residues | 25 |
Details | binding site for residue TPP E 602 |
Chain | Residue |
E | GLY384 |
E | ASP385 |
E | GLY408 |
E | HIS409 |
E | ILE410 |
E | GLY434 |
E | ASP435 |
E | GLY436 |
E | SER437 |
E | ASN462 |
E | GLY464 |
E | TYR465 |
E | VAL466 |
E | ILE467 |
E | GLU468 |
E | MG601 |
E | HOH701 |
E | HOH728 |
E | HOH744 |
F | ALA24 |
F | GLY25 |
F | GLU49 |
F | VAL74 |
F | HIS113 |
F | EDO601 |
site_id | AD3 |
Number of Residues | 5 |
Details | binding site for residue EDO F 601 |
Chain | Residue |
E | TYR289 |
E | GLU468 |
E | TPP602 |
F | ASP26 |
F | HIS113 |
site_id | AD4 |
Number of Residues | 5 |
Details | binding site for residue MG F 602 |
Chain | Residue |
F | ASP435 |
F | ASN462 |
F | GLY464 |
F | TPP603 |
F | HOH825 |
site_id | AD5 |
Number of Residues | 23 |
Details | binding site for residue TPP F 603 |
Chain | Residue |
E | ALA24 |
E | GLY25 |
E | GLU49 |
E | VAL74 |
E | HIS113 |
F | ASP385 |
F | GLY408 |
F | HIS409 |
F | ILE410 |
F | GLY434 |
F | ASP435 |
F | GLY436 |
F | SER437 |
F | ASN462 |
F | GLY464 |
F | TYR465 |
F | VAL466 |
F | ILE467 |
F | GLU468 |
F | MG602 |
F | HOH701 |
F | HOH721 |
F | HOH825 |
site_id | AD6 |
Number of Residues | 5 |
Details | binding site for residue MG G 601 |
Chain | Residue |
G | ASP435 |
G | ASN462 |
G | GLY464 |
G | TPP602 |
G | HOH809 |
site_id | AD7 |
Number of Residues | 24 |
Details | binding site for residue TPP G 602 |
Chain | Residue |
G | GLY384 |
G | ASP385 |
G | GLY408 |
G | HIS409 |
G | ILE410 |
G | GLY434 |
G | ASP435 |
G | GLY436 |
G | SER437 |
G | ASN462 |
G | GLY464 |
G | TYR465 |
G | VAL466 |
G | ILE467 |
G | GLU468 |
G | MG601 |
G | HOH784 |
G | HOH809 |
G | HOH818 |
H | ALA24 |
H | GLY25 |
H | GLU49 |
H | VAL74 |
H | HIS113 |
site_id | AD8 |
Number of Residues | 5 |
Details | binding site for residue MG H 601 |
Chain | Residue |
H | ASP435 |
H | ASN462 |
H | GLY464 |
H | TPP602 |
H | HOH762 |
site_id | AD9 |
Number of Residues | 24 |
Details | binding site for residue TPP H 602 |
Chain | Residue |
G | ALA24 |
G | GLY25 |
G | GLU49 |
G | VAL74 |
G | HIS113 |
H | ASP385 |
H | GLY408 |
H | HIS409 |
H | ILE410 |
H | GLY434 |
H | ASP435 |
H | GLY436 |
H | SER437 |
H | ASN462 |
H | GLY464 |
H | TYR465 |
H | VAL466 |
H | ILE467 |
H | GLU468 |
H | MG601 |
H | HOH724 |
H | HOH754 |
H | HOH762 |
H | HOH786 |
site_id | AE1 |
Number of Residues | 5 |
Details | binding site for residue MG I 601 |
Chain | Residue |
I | ASP435 |
I | ASN462 |
I | GLY464 |
I | TPP602 |
I | HOH728 |
site_id | AE2 |
Number of Residues | 25 |
Details | binding site for residue TPP I 602 |
Chain | Residue |
I | ASP385 |
I | GLY408 |
I | HIS409 |
I | ILE410 |
I | GLY434 |
I | ASP435 |
I | GLY436 |
I | SER437 |
I | ASN462 |
I | GLY464 |
I | TYR465 |
I | VAL466 |
I | ILE467 |
I | GLU468 |
I | MG601 |
I | EDO603 |
I | HOH702 |
I | HOH728 |
I | HOH775 |
I | HOH784 |
J | ALA24 |
J | GLY25 |
J | GLU49 |
J | VAL74 |
J | HIS113 |
site_id | AE3 |
Number of Residues | 5 |
Details | binding site for residue EDO I 603 |
Chain | Residue |
I | TYR289 |
I | GLU468 |
I | TPP602 |
J | ASP26 |
J | HIS113 |
site_id | AE4 |
Number of Residues | 5 |
Details | binding site for residue MG J 601 |
Chain | Residue |
J | ASP435 |
J | ASN462 |
J | GLY464 |
J | TPP602 |
J | HOH751 |
site_id | AE5 |
Number of Residues | 24 |
Details | binding site for residue TPP J 602 |
Chain | Residue |
I | ALA24 |
I | GLY25 |
I | GLU49 |
I | VAL74 |
I | HIS113 |
J | GLY384 |
J | ASP385 |
J | GLY408 |
J | HIS409 |
J | ILE410 |
J | GLY434 |
J | ASP435 |
J | GLY436 |
J | SER437 |
J | ASN462 |
J | GLY464 |
J | TYR465 |
J | VAL466 |
J | ILE467 |
J | GLU468 |
J | MG601 |
J | HOH707 |
J | HOH751 |
J | HOH752 |
site_id | AE6 |
Number of Residues | 5 |
Details | binding site for residue MG K 601 |
Chain | Residue |
K | ASP435 |
K | ASN462 |
K | GLY464 |
K | TPP602 |
K | HOH776 |
site_id | AE7 |
Number of Residues | 25 |
Details | binding site for residue TPP K 602 |
Chain | Residue |
K | GLY384 |
K | ASP385 |
K | GLY408 |
K | HIS409 |
K | ILE410 |
K | GLY434 |
K | ASP435 |
K | GLY436 |
K | SER437 |
K | LEU440 |
K | ASN462 |
K | GLY464 |
K | TYR465 |
K | VAL466 |
K | ILE467 |
K | GLU468 |
K | MG601 |
K | HOH702 |
K | HOH757 |
K | HOH776 |
L | ALA24 |
L | GLY25 |
L | GLU49 |
L | VAL74 |
L | HIS113 |
site_id | AE8 |
Number of Residues | 5 |
Details | binding site for residue MG L 601 |
Chain | Residue |
L | ASP435 |
L | ASN462 |
L | GLY464 |
L | TPP602 |
L | HOH805 |
site_id | AE9 |
Number of Residues | 24 |
Details | binding site for residue TPP L 602 |
Chain | Residue |
K | ALA24 |
K | GLY25 |
K | GLU49 |
K | VAL74 |
K | HIS113 |
L | GLY384 |
L | ASP385 |
L | GLY408 |
L | HIS409 |
L | ILE410 |
L | GLY434 |
L | ASP435 |
L | GLY436 |
L | SER437 |
L | ASN462 |
L | GLY464 |
L | TYR465 |
L | VAL466 |
L | ILE467 |
L | GLU468 |
L | MG601 |
L | HOH728 |
L | HOH794 |
L | HOH805 |
site_id | AF1 |
Number of Residues | 5 |
Details | binding site for residue MG M 601 |
Chain | Residue |
M | ASP435 |
M | ASN462 |
M | GLY464 |
M | TPP602 |
M | HOH730 |
site_id | AF2 |
Number of Residues | 23 |
Details | binding site for residue TPP M 602 |
Chain | Residue |
M | ASP385 |
M | GLY408 |
M | HIS409 |
M | ILE410 |
M | GLY434 |
M | ASP435 |
M | GLY436 |
M | SER437 |
M | ASN462 |
M | GLY464 |
M | TYR465 |
M | VAL466 |
M | ILE467 |
M | GLU468 |
M | MG601 |
M | HOH704 |
M | HOH730 |
M | HOH739 |
N | ALA24 |
N | GLY25 |
N | GLU49 |
N | VAL74 |
N | HIS113 |
site_id | AF3 |
Number of Residues | 5 |
Details | binding site for residue MG N 601 |
Chain | Residue |
N | ASP435 |
N | ASN462 |
N | GLY464 |
N | TPP602 |
N | HOH770 |
site_id | AF4 |
Number of Residues | 25 |
Details | binding site for residue TPP N 602 |
Chain | Residue |
M | ALA24 |
M | GLY25 |
M | GLU49 |
M | VAL74 |
M | HIS113 |
N | GLY384 |
N | ASP385 |
N | GLY408 |
N | HIS409 |
N | ILE410 |
N | GLY434 |
N | ASP435 |
N | GLY436 |
N | SER437 |
N | ASN462 |
N | GLY464 |
N | TYR465 |
N | VAL466 |
N | ILE467 |
N | GLU468 |
N | MG601 |
N | EDO603 |
N | HOH701 |
N | HOH725 |
N | HOH770 |
site_id | AF5 |
Number of Residues | 5 |
Details | binding site for residue EDO N 603 |
Chain | Residue |
M | ASP26 |
M | HIS113 |
N | TYR289 |
N | GLU468 |
N | TPP602 |
site_id | AF6 |
Number of Residues | 5 |
Details | binding site for residue MG O 601 |
Chain | Residue |
O | ASP435 |
O | ASN462 |
O | GLY464 |
O | TPP602 |
O | HOH712 |
site_id | AF7 |
Number of Residues | 23 |
Details | binding site for residue TPP O 602 |
Chain | Residue |
O | ASP385 |
O | GLY408 |
O | HIS409 |
O | ILE410 |
O | GLY434 |
O | ASP435 |
O | GLY436 |
O | SER437 |
O | ASN462 |
O | GLY464 |
O | TYR465 |
O | VAL466 |
O | ILE467 |
O | GLU468 |
O | MG601 |
O | HOH705 |
O | HOH712 |
O | HOH762 |
P | ALA24 |
P | GLY25 |
P | GLU49 |
P | VAL74 |
P | HIS113 |
site_id | AF8 |
Number of Residues | 5 |
Details | binding site for residue MG P 601 |
Chain | Residue |
P | ASP435 |
P | ASN462 |
P | GLY464 |
P | TPP602 |
P | HOH785 |
site_id | AF9 |
Number of Residues | 25 |
Details | binding site for residue TPP P 602 |
Chain | Residue |
O | ALA24 |
O | GLY25 |
O | GLU49 |
O | VAL74 |
O | HIS113 |
P | GLY384 |
P | ASP385 |
P | GLY408 |
P | HIS409 |
P | ILE410 |
P | GLY434 |
P | ASP435 |
P | GLY436 |
P | SER437 |
P | ASN462 |
P | GLY464 |
P | TYR465 |
P | VAL466 |
P | ILE467 |
P | GLU468 |
P | MG601 |
P | HOH744 |
P | HOH753 |
P | HOH785 |
P | HOH876 |
site_id | AG1 |
Number of Residues | 5 |
Details | binding site for residue MG Q 601 |
Chain | Residue |
Q | ASP435 |
Q | ASN462 |
Q | GLY464 |
Q | TPP602 |
Q | HOH785 |
site_id | AG2 |
Number of Residues | 26 |
Details | binding site for residue TPP Q 602 |
Chain | Residue |
Q | GLY384 |
Q | ASP385 |
Q | GLY408 |
Q | HIS409 |
Q | ILE410 |
Q | GLY434 |
Q | ASP435 |
Q | GLY436 |
Q | SER437 |
Q | ASN462 |
Q | GLY464 |
Q | TYR465 |
Q | VAL466 |
Q | ILE467 |
Q | GLU468 |
Q | MG601 |
Q | EDO603 |
Q | HOH736 |
Q | HOH748 |
Q | HOH785 |
Q | HOH808 |
R | ALA24 |
R | GLY25 |
R | GLU49 |
R | VAL74 |
R | HIS113 |
site_id | AG3 |
Number of Residues | 5 |
Details | binding site for residue EDO Q 603 |
Chain | Residue |
Q | TYR289 |
Q | THR383 |
Q | GLU468 |
Q | TPP602 |
R | ASP26 |
site_id | AG4 |
Number of Residues | 5 |
Details | binding site for residue MG R 601 |
Chain | Residue |
R | ASP435 |
R | ASN462 |
R | GLY464 |
R | TPP602 |
R | HOH735 |
site_id | AG5 |
Number of Residues | 25 |
Details | binding site for residue TPP R 602 |
Chain | Residue |
Q | ALA24 |
Q | GLY25 |
Q | GLU49 |
Q | VAL74 |
Q | HIS113 |
R | GLY384 |
R | ASP385 |
R | GLY408 |
R | HIS409 |
R | ILE410 |
R | GLY434 |
R | ASP435 |
R | GLY436 |
R | SER437 |
R | ASN462 |
R | GLY464 |
R | TYR465 |
R | VAL466 |
R | ILE467 |
R | GLU468 |
R | MG601 |
R | EDO603 |
R | HOH735 |
R | HOH737 |
R | HOH755 |
site_id | AG6 |
Number of Residues | 6 |
Details | binding site for residue EDO R 603 |
Chain | Residue |
Q | ASP26 |
Q | HIS113 |
R | TYR289 |
R | GLU468 |
R | ILE471 |
R | TPP602 |
site_id | AG7 |
Number of Residues | 5 |
Details | binding site for residue MG S 601 |
Chain | Residue |
S | ASP435 |
S | ASN462 |
S | GLY464 |
S | TPP602 |
S | HOH756 |
site_id | AG8 |
Number of Residues | 23 |
Details | binding site for residue TPP S 602 |
Chain | Residue |
S | ASP385 |
S | GLY408 |
S | HIS409 |
S | ILE410 |
S | GLY434 |
S | ASP435 |
S | GLY436 |
S | SER437 |
S | ASN462 |
S | GLY464 |
S | TYR465 |
S | VAL466 |
S | ILE467 |
S | GLU468 |
S | MG601 |
S | HOH702 |
S | HOH748 |
S | HOH756 |
T | ALA24 |
T | GLY25 |
T | GLU49 |
T | VAL74 |
T | HIS113 |
site_id | AG9 |
Number of Residues | 5 |
Details | binding site for residue MG T 601 |
Chain | Residue |
T | ASP435 |
T | ASN462 |
T | GLY464 |
T | TPP602 |
T | HOH773 |
site_id | AH1 |
Number of Residues | 23 |
Details | binding site for residue TPP T 602 |
Chain | Residue |
S | ALA24 |
S | GLY25 |
S | GLU49 |
S | VAL74 |
S | HIS113 |
T | ASP385 |
T | GLY408 |
T | HIS409 |
T | ILE410 |
T | GLY434 |
T | ASP435 |
T | GLY436 |
T | SER437 |
T | ASN462 |
T | GLY464 |
T | TYR465 |
T | VAL466 |
T | ILE467 |
T | GLU468 |
T | MG601 |
T | HOH734 |
T | HOH770 |
T | HOH773 |
site_id | AH2 |
Number of Residues | 5 |
Details | binding site for residue MG U 601 |
Chain | Residue |
U | ASP435 |
U | ASN462 |
U | GLY464 |
U | TPP602 |
U | HOH752 |
site_id | AH3 |
Number of Residues | 23 |
Details | binding site for residue TPP U 602 |
Chain | Residue |
U | GLY384 |
U | ASP385 |
U | GLY408 |
U | HIS409 |
U | ILE410 |
U | GLY434 |
U | ASP435 |
U | GLY436 |
U | SER437 |
U | ASN462 |
U | GLY464 |
U | TYR465 |
U | VAL466 |
U | ILE467 |
U | GLU468 |
U | MG601 |
U | HOH741 |
U | HOH752 |
V | ALA24 |
V | GLY25 |
V | GLU49 |
V | VAL74 |
V | HIS113 |
site_id | AH4 |
Number of Residues | 5 |
Details | binding site for residue MG V 601 |
Chain | Residue |
V | ASP435 |
V | ASN462 |
V | GLY464 |
V | TPP602 |
V | HOH739 |
site_id | AH5 |
Number of Residues | 24 |
Details | binding site for residue TPP V 602 |
Chain | Residue |
U | ALA24 |
U | GLY25 |
U | GLU49 |
U | VAL74 |
U | HIS113 |
V | GLY384 |
V | ASP385 |
V | GLY408 |
V | HIS409 |
V | ILE410 |
V | GLY434 |
V | ASP435 |
V | GLY436 |
V | SER437 |
V | ASN462 |
V | GLY464 |
V | TYR465 |
V | VAL466 |
V | ILE467 |
V | GLU468 |
V | MG601 |
V | HOH711 |
V | HOH725 |
V | HOH739 |
site_id | AH6 |
Number of Residues | 5 |
Details | binding site for residue MG W 601 |
Chain | Residue |
W | ASP435 |
W | ASN462 |
W | GLY464 |
W | TPP602 |
W | HOH736 |
site_id | AH7 |
Number of Residues | 22 |
Details | binding site for residue TPP W 602 |
Chain | Residue |
W | GLY384 |
W | ASP385 |
W | GLY408 |
W | HIS409 |
W | ILE410 |
W | GLY434 |
W | ASP435 |
W | GLY436 |
W | SER437 |
W | ASN462 |
W | GLY464 |
W | TYR465 |
W | VAL466 |
W | ILE467 |
W | GLU468 |
W | MG601 |
W | HOH718 |
W | HOH736 |
X | ALA24 |
X | GLU49 |
X | VAL74 |
X | HIS113 |
site_id | AH8 |
Number of Residues | 5 |
Details | binding site for residue MG X 601 |
Chain | Residue |
X | ASP435 |
X | ASN462 |
X | GLY464 |
X | TPP602 |
X | HOH756 |
site_id | AH9 |
Number of Residues | 23 |
Details | binding site for residue TPP X 602 |
Chain | Residue |
W | ALA24 |
W | GLY25 |
W | GLU49 |
W | VAL74 |
W | HIS113 |
X | ASP385 |
X | GLY408 |
X | HIS409 |
X | ILE410 |
X | GLY434 |
X | ASP435 |
X | GLY436 |
X | SER437 |
X | ASN462 |
X | GLY464 |
X | TYR465 |
X | VAL466 |
X | ILE467 |
X | GLU468 |
X | MG601 |
X | HOH729 |
X | HOH756 |
X | HOH767 |
Functional Information from PROSITE/UniProt
site_id | PS00187 |
Number of Residues | 20 |
Details | TPP_ENZYMES Thiamine pyrophosphate enzymes signature. FGnavgsPerrhImMvGDGS |
Chain | Residue | Details |
A | PHE418-SER437 |