5EUE

S1P Lyase Bacterial Surrogate bound to N-(2-((4-methoxy-2,5-dimethylbenzyl)amino)-1-phenylethyl)-5-methylisoxazole-3-carboxamide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
A	0008117	molecular_function	sphinganine-1-phosphate aldolase activity
A	0016020	cellular_component	membrane
A	0016829	molecular_function	lyase activity
A	0016830	molecular_function	carbon-carbon lyase activity
A	0019752	biological_process	carboxylic acid metabolic process
A	0030149	biological_process	sphingolipid catabolic process
A	0030170	molecular_function	pyridoxal phosphate binding
A	0042802	molecular_function	identical protein binding
B	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
B	0008117	molecular_function	sphinganine-1-phosphate aldolase activity
B	0016020	cellular_component	membrane
B	0016829	molecular_function	lyase activity
B	0016830	molecular_function	carbon-carbon lyase activity
B	0019752	biological_process	carboxylic acid metabolic process
B	0030149	biological_process	sphingolipid catabolic process
B	0030170	molecular_function	pyridoxal phosphate binding
B	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue 5S5 A 601

Chain	Residue
A	PRO127
B	SER497
B	PHE500
A	PRO130
A	TRP340
A	ILE344
A	TYR345
A	ALA346
B	PHE249
B	ASN432
B	VAL496

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site_id	AC2
Number of Residues	5
Details	binding site for residue PO4 A 602

Chain	Residue
A	ALA103
A	TYR105
A	LYS317
B	ASN126
B	HIS129

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site_id	AC3
Number of Residues	5
Details	binding site for residue PO4 B 601

Chain	Residue
A	ASN126
A	HIS129
B	ALA103
B	TYR105
B	LLP311

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site_id	AC4
Number of Residues	10
Details	binding site for residue 5S5 B 602

Chain	Residue
A	PHE249
A	VAL496
A	PHE500
B	PRO127
B	LEU128
B	PRO130
B	TRP340
B	ILE344
B	TYR345
B	ALA346

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