5EU1
CRYSTAL STRUCTURE OF BRD9 IN COMPLEX WITH BI-7273
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue 5SW A 201 |
| Chain | Residue |
| A | HIS42 |
| A | HOH305 |
| A | HOH369 |
| A | PHE44 |
| A | PHE45 |
| A | PHE47 |
| A | VAL49 |
| A | ILE53 |
| A | ALA54 |
| A | ASN100 |
| A | TYR106 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue 5SW B 201 |
| Chain | Residue |
| A | LYS80 |
| A | GLU124 |
| B | HIS42 |
| B | PHE44 |
| B | PHE45 |
| B | PHE47 |
| B | VAL49 |
| B | ILE53 |
| B | ASN100 |
| B | TYR106 |
| B | HOH301 |
| B | HOH317 |
| B | HOH361 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding => ECO:0000269|PubMed:26365797 |
| Chain | Residue | Details |
| A | ILE53 | |
| A | TYR106 | |
| B | ILE53 | |
| B | TYR106 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q3UQU0 |
| Chain | Residue | Details |
| B | GLY56 | |
| A | GLY56 |
