Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003848 | molecular_function | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| A | 0046656 | biological_process | folic acid biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue APC A 201 |
| Chain | Residue |
| A | LEU71 |
| A | SER112 |
| A | HIS115 |
| A | ARG117 |
| A | ARG121 |
| A | MG203 |
| A | MG204 |
| A | HOH304 |
| A | HOH308 |
| A | HOH320 |
| A | HOH321 |
| A | ARG83 |
| A | HOH324 |
| A | HOH326 |
| A | HOH330 |
| A | HOH334 |
| A | ARG88 |
| A | ARG92 |
| A | ASP95 |
| A | ASP97 |
| A | ILE98 |
| A | LYS110 |
| A | LEU111 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue 5RZ A 202 |
| Chain | Residue |
| A | THR43 |
| A | ALA44 |
| A | PRO45 |
| A | VAL46 |
| A | GLY47 |
| A | PHE54 |
| A | ASN56 |
| A | ARG88 |
| A | GLU104 |
| A | MET105 |
| A | ARG121 |
| A | PHE123 |
| A | HOH320 |
| A | HOH346 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 203 |
| Chain | Residue |
| A | ASP95 |
| A | ASP97 |
| A | APC201 |
| A | MG204 |
| A | HOH320 |
| A | HOH358 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 204 |
| Chain | Residue |
| A | ASP95 |
| A | ASP97 |
| A | APC201 |
| A | MG203 |
| A | HOH324 |
| A | HOH326 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue NO3 A 205 |
| Chain | Residue |
| A | ILE12 |
| A | ARG83 |
| A | ILE84 |
| A | ARG85 |
| A | ARG92 |
| A | THR93 |
Functional Information from PROSITE/UniProt
| site_id | PS00794 |
| Number of Residues | 12 |
| Details | HPPK 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. RwGPRtlDVDIL |
| Chain | Residue | Details |
| A | ARG88-LEU99 | |
