5EQU

Crystal structure of the epimerase SnoN in complex with Fe3+, alpha ketoglutarate and nogalamycin RO

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
A	0046872	molecular_function	metal ion binding
B	0005506	molecular_function	iron ion binding
B	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
B	0046872	molecular_function	metal ion binding
C	0005506	molecular_function	iron ion binding
C	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
C	0046872	molecular_function	metal ion binding
D	0005506	molecular_function	iron ion binding
D	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue FE A 300

Chain	Residue
A	HIS130
A	ASP132
A	HIS213
A	AKG301
A	HOH401

---

site_id	AC2
Number of Residues	14
Details	binding site for residue AKG A 301

Chain	Residue
A	ASP132
A	TRP148
A	HIS207
A	HIS213
A	ALA215
A	ARG224
A	SER228
A	FE300
A	HOH401
A	HOH443
A	MET72
A	LEU114
A	THR127
A	HIS130

---

site_id	AC3
Number of Residues	15
Details	binding site for residue 5R6 A 302

Chain	Residue
A	GLU47
A	GLU51
A	TRP64
A	GLY65
A	TYR74
A	LYS110
A	GLU112
A	HIS130
A	ASP132
A	TRP180
A	PHE245
A	LEU246
A	HOH409
A	HOH418
A	HOH494

---

site_id	AC4
Number of Residues	5
Details	binding site for residue FE B 300

Chain	Residue
B	HIS130
B	ASP132
B	HIS213
B	AKG301
B	HOH414

---

site_id	AC5
Number of Residues	16
Details	binding site for residue AKG B 301

Chain	Residue
B	MET72
B	LEU114
B	LYS116
B	THR127
B	HIS130
B	ASP132
B	TRP148
B	MET161
B	HIS207
B	HIS213
B	ALA215
B	ARG224
B	SER228
B	FE300
B	HOH404
B	HOH414

---

site_id	AC6
Number of Residues	11
Details	binding site for residue 5R6 B 302

Chain	Residue
B	TRP64
B	GLY65
B	SER66
B	TYR74
B	LYS110
B	GLU112
B	HIS130
B	ASP132
B	TRP180
B	PHE245
B	LEU246

---

site_id	AC7
Number of Residues	5
Details	binding site for residue FE C 300

Chain	Residue
C	HIS130
C	ASP132
C	HIS213
C	AKG301
C	HOH406

---

site_id	AC8
Number of Residues	16
Details	binding site for residue AKG C 301

Chain	Residue
C	MET72
C	LEU114
C	LYS116
C	THR127
C	HIS130
C	ASP132
C	THR146
C	TRP148
C	HIS207
C	HIS213
C	ALA215
C	ARG224
C	SER228
C	FE300
C	HOH406
C	HOH425

---

site_id	AC9
Number of Residues	13
Details	binding site for residue 5R6 C 302

Chain	Residue
C	HOH450
C	TRP64
C	GLY65
C	SER66
C	MET72
C	TYR74
C	LYS110
C	GLU112
C	HIS130
C	ASP132
C	TRP180
C	PHE245
C	LEU246

---

site_id	AD1
Number of Residues	5
Details	binding site for residue FE D 300

Chain	Residue
D	HIS130
D	ASP132
D	HIS213
D	AKG301
D	HOH404

---

site_id	AD2
Number of Residues	15
Details	binding site for residue AKG D 301

Chain	Residue
D	MET72
D	LEU114
D	LYS116
D	THR127
D	HIS130
D	ASP132
D	TRP148
D	HIS207
D	HIS213
D	ALA215
D	ARG224
D	SER228
D	FE300
D	HOH404
D	HOH405

---

site_id	AD3
Number of Residues	12
Details	binding site for residue 5R6 D 302

Chain	Residue
D	TRP64
D	GLY65
D	SER66
D	TYR74
D	LYS110
D	GLU112
D	LEU114
D	HIS130
D	ASP132
D	TRP180
D	PHE245
D	LEU246

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