5EPB

Crystal structure of the bromodomain of human ATAD2 in complex with Compound 49

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006325	biological_process	chromatin organization
A	0006355	biological_process	regulation of transcription, DNA-templated
A	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue 5QW A 1201

Chain	Residue
A	VAL1008
A	HOH1328
A	HOH1342
A	HOH1362
A	VAL1013
A	ASN1064
A	ILE1074
A	GLU1095
A	ASP1096
A	5QW1202
A	HOH1305
A	HOH1318

---

site_id	AC2
Number of Residues	11
Details	binding site for residue 5QW A 1202

Chain	Residue
A	ARG1007
A	VAL1008
A	THR1010
A	LYS1011
A	PRO1012
A	VAL1013
A	ASP1014
A	VAL1018
A	5QW1201
A	HOH1342
A	HOH1411

---

site_id	AC3
Number of Residues	7
Details	binding site for residue SO4 A 1203

Chain	Residue
A	ARG987
A	ARG990
A	ARG994
A	ARG1067
A	ARG1072
A	HOH1371
A	HOH1418

---