5EP8

X-Ray Structure of the Complex Pyrimidine-nucleoside phosphorylase from Bacillus subtilis with Sulfate Ion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
A	0004850	molecular_function	uridine phosphorylase activity
A	0005829	cellular_component	cytosol
A	0006206	biological_process	pyrimidine nucleobase metabolic process
A	0006213	biological_process	pyrimidine nucleoside metabolic process
A	0009032	molecular_function	thymidine phosphorylase activity
A	0016154	molecular_function	pyrimidine-nucleoside phosphorylase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0046872	molecular_function	metal ion binding
A	0047847	molecular_function	deoxyuridine phosphorylase activity
B	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
B	0004850	molecular_function	uridine phosphorylase activity
B	0005829	cellular_component	cytosol
B	0006206	biological_process	pyrimidine nucleobase metabolic process
B	0006213	biological_process	pyrimidine nucleoside metabolic process
B	0009032	molecular_function	thymidine phosphorylase activity
B	0016154	molecular_function	pyrimidine-nucleoside phosphorylase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0046872	molecular_function	metal ion binding
B	0047847	molecular_function	deoxyuridine phosphorylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 501

Chain	Residue
A	LYS81
A	THR92
A	LYS108
A	SER110
A	THR120
A	HOH607

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site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 B 501

Chain	Residue
B	LYS108
B	SER110
B	THR120

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site_id	AC3
Number of Residues	5
Details	binding site for residue NA B 502

Chain	Residue
B	GLY88
B	THR90
B	LEU243
B	ALA246
B	GLU255

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Functional Information from PROSITE/UniProt

site_id	PS00647
Number of Residues	16
Details	THYMID_PHOSPHORYLASE Thymidine and pyrimidine-nucleoside phosphorylases signature. SGRGLghTGGTiDkLE

Chain	Residue	Details
A	SER110-GLU125

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P77836

Chain	Residue	Details
A	LYS81
A	ALA246
A	GLU255
B	LYS81
B	GLY88
B	THR90
B	THR92
B	LYS108
B	THR120
B	ARG168
B	LYS187
A	GLY88
B	LEU243
B	ALA246
B	GLU255
A	THR90
A	THR92
A	LYS108
A	THR120
A	ARG168
A	LYS187
A	LEU243

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