Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000947 | biological_process | amino acid catabolic process to alcohol via Ehrlich pathway |
| A | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| A | 0004552 | molecular_function | octanol dehydrogenase (NAD+) activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019170 | molecular_function | methylglyoxal reductase (NADH) activity |
| A | 0019655 | biological_process | pyruvate fermentation to ethanol |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047655 | molecular_function | allyl-alcohol dehydrogenase activity |
| A | 0120542 | molecular_function | ethanol dehydrogenase (NAD+) activity |
| A | 1904408 | molecular_function | melatonin binding |
| A | 1990362 | molecular_function | butanol dehydrogenase (NAD+) activity |
| B | 0000947 | biological_process | amino acid catabolic process to alcohol via Ehrlich pathway |
| B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| B | 0004552 | molecular_function | octanol dehydrogenase (NAD+) activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019170 | molecular_function | methylglyoxal reductase (NADH) activity |
| B | 0019655 | biological_process | pyruvate fermentation to ethanol |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047655 | molecular_function | allyl-alcohol dehydrogenase activity |
| B | 0120542 | molecular_function | ethanol dehydrogenase (NAD+) activity |
| B | 1904408 | molecular_function | melatonin binding |
| B | 1990362 | molecular_function | butanol dehydrogenase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | CYS43 |
| A | THR45 |
| A | HIS66 |
| A | CYS153 |
| A | NAD403 |
| A | ETF404 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 402 |
| Chain | Residue |
| A | CYS111 |
| A | CYS97 |
| A | CYS100 |
| A | CYS103 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | binding site for residue NAD A 403 |
| Chain | Residue |
| A | HIS44 |
| A | THR45 |
| A | HIS48 |
| A | TRP54 |
| A | THR157 |
| A | SER176 |
| A | GLY177 |
| A | ALA179 |
| A | GLY180 |
| A | GLY181 |
| A | LEU182 |
| A | ASP201 |
| A | LYS206 |
| A | PHE221 |
| A | SER246 |
| A | VAL268 |
| A | GLY269 |
| A | MET270 |
| A | SER293 |
| A | VAL295 |
| A | ARG340 |
| A | ZN401 |
| A | ETF404 |
| A | HOH508 |
| B | VAL284 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue ETF A 404 |
| Chain | Residue |
| A | THR45 |
| A | TRP54 |
| A | HIS66 |
| A | TRP92 |
| A | CYS153 |
| A | MET270 |
| A | TYR294 |
| A | ZN401 |
| A | NAD403 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 401 |
| Chain | Residue |
| B | CYS43 |
| B | HIS66 |
| B | GLU67 |
| B | CYS153 |
| B | ETF404 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 402 |
| Chain | Residue |
| B | CYS97 |
| B | CYS100 |
| B | CYS103 |
| B | CYS111 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | binding site for residue NAD B 403 |
| Chain | Residue |
| A | VAL284 |
| B | HIS44 |
| B | GLY177 |
| B | GLY180 |
| B | GLY181 |
| B | LEU182 |
| B | ILE200 |
| B | ASP201 |
| B | LYS206 |
| B | PHE221 |
| B | VAL245 |
| B | SER246 |
| B | VAL247 |
| B | ALA251 |
| B | VAL268 |
| B | MET270 |
| B | SER293 |
| B | TYR294 |
| B | VAL295 |
| B | ETF404 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue ETF B 404 |
| Chain | Residue |
| B | THR45 |
| B | HIS66 |
| B | TRP92 |
| B | CYS153 |
| B | TYR294 |
| B | ZN401 |
| B | NAD403 |
Functional Information from PROSITE/UniProt
| site_id | PS00059 |
| Number of Residues | 15 |
| Details | ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEgAGVvvgmGenV |
| Chain | Residue | Details |
| A | GLY65-VAL79 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25157460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26743849","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4W6Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ENV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26743849","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ENV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"in the open conformation","evidences":[{"source":"PubMed","id":"25157460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26743849","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4W6Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ENV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"320000","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"15665377","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 10 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
