5ENM

Compound 10

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004190	molecular_function	aspartic-type endopeptidase activity
A	0006508	biological_process	proteolysis
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL A 501

Chain	Residue
A	GLN103
A	TYR108
A	ILE227
A	ASP394
A	ARG397
A	ARG399

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site_id	AC2
Number of Residues	1
Details	binding site for residue IOD A 502

Chain	Residue
A	SER153

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site_id	AC3
Number of Residues	13
Details	binding site for residue 5QU A 503

Chain	Residue
A	GLY61
A	ASP80
A	TYR119
A	GLN121
A	PHE156
A	ILE158
A	TRP163
A	ASP276
A	GLY278
A	HOH603
A	HOH626
A	GLY59
A	GLN60

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Functional Information from PROSITE/UniProt

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV

Chain	Residue	Details
A	ILE77-VAL88

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	7
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"17425515","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19011241","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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