5EKU
Crystal Structure of Trypanosoma Brucei Protein Arginine Methyltransferase PRMT7 in complex with S-Adenosyl-L-homocysteine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016274 | molecular_function | protein-arginine N-methyltransferase activity |
| A | 0018216 | biological_process | peptidyl-arginine methylation |
| A | 0032259 | biological_process | methylation |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0016274 | molecular_function | protein-arginine N-methyltransferase activity |
| B | 0018216 | biological_process | peptidyl-arginine methylation |
| B | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue SAH A 401 |
| Chain | Residue |
| A | MET75 |
| A | VAL124 |
| A | GLU125 |
| A | GLY126 |
| A | LEU130 |
| A | MET153 |
| A | SER154 |
| A | GLU172 |
| A | TYR186 |
| A | ARG81 |
| A | GLU101 |
| A | ILE102 |
| A | GLY103 |
| A | ALA104 |
| A | GLY105 |
| A | SER106 |
| A | LEU109 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue SAH B 401 |
| Chain | Residue |
| B | MET75 |
| B | ARG81 |
| B | GLU101 |
| B | GLY103 |
| B | ALA104 |
| B | SER106 |
| B | LEU109 |
| B | GLU125 |
| B | GLY126 |
| B | LEU130 |
| B | MET153 |
| B | SER154 |
| B | GLU172 |
| B | TYR186 |
