5EKC
Thermostable aldehyde dehydrogenase from Pyrobaculum sp.1860 complexed with NADP+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue NAP A 500 |
| Chain | Residue |
| A | ILE151 |
| A | GLY211 |
| A | GLY215 |
| A | PHE229 |
| A | GLY231 |
| A | GLU232 |
| A | THR235 |
| A | ASN332 |
| A | ARG334 |
| A | GLN335 |
| A | HOH604 |
| A | THR152 |
| A | HOH643 |
| A | HOH651 |
| A | HOH729 |
| A | HOH751 |
| A | HOH763 |
| A | HOH860 |
| A | PRO153 |
| A | TRP154 |
| A | LYS178 |
| A | PRO179 |
| A | ALA180 |
| A | SER181 |
| A | ASP182 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue NAP B 500 |
| Chain | Residue |
| B | ILE151 |
| B | THR152 |
| B | PRO153 |
| B | TRP154 |
| B | LYS178 |
| B | ALA180 |
| B | SER181 |
| B | PRO210 |
| B | GLY211 |
| B | GLY215 |
| B | PHE229 |
| B | GLY231 |
| B | GLU232 |
| B | THR235 |
| B | ASN332 |
| B | GLN335 |
| B | HOH609 |
| B | HOH670 |
| B | HOH701 |
| B | HOH702 |
| B | HOH727 |
| B | HOH751 |
| B | HOH834 |
| B | HOH875 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | binding site for residue NAP C 500 |
| Chain | Residue |
| C | ILE151 |
| C | THR152 |
| C | PRO153 |
| C | TRP154 |
| C | LYS178 |
| C | ALA180 |
| C | SER181 |
| C | PRO210 |
| C | GLY211 |
| C | GLY215 |
| C | PHE229 |
| C | GLY231 |
| C | GLU232 |
| C | THR235 |
| C | GLU238 |
| C | ASN332 |
| C | ARG334 |
| C | GLN335 |
| C | HOH605 |
| C | HOH618 |
| C | HOH642 |
| C | HOH704 |
| C | HOH810 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | binding site for residue NAP D 500 |
| Chain | Residue |
| D | ILE151 |
| D | THR152 |
| D | PRO153 |
| D | TRP154 |
| D | LYS178 |
| D | ALA180 |
| D | SER181 |
| D | GLY211 |
| D | GLY215 |
| D | PHE229 |
| D | THR230 |
| D | GLY231 |
| D | GLU232 |
| D | THR235 |
| D | ASN332 |
| D | GLN335 |
| D | HOH604 |
| D | HOH610 |
| D | HOH646 |
| D | HOH716 |
| D | HOH761 |
| D | HOH820 |
| site_id | AC5 |
| Number of Residues | 24 |
| Details | binding site for residue NAP E 500 |
| Chain | Residue |
| E | PRO179 |
| E | ALA180 |
| E | SER181 |
| E | PRO210 |
| E | GLY211 |
| E | GLY215 |
| E | PHE229 |
| E | GLY231 |
| E | GLU232 |
| E | THR235 |
| E | ASN332 |
| E | ARG334 |
| E | GLN335 |
| E | HOH619 |
| E | HOH630 |
| E | HOH634 |
| E | HOH657 |
| E | HOH679 |
| E | HOH811 |
| E | ILE151 |
| E | THR152 |
| E | PRO153 |
| E | TRP154 |
| E | LYS178 |
| site_id | AC6 |
| Number of Residues | 22 |
| Details | binding site for residue NAP F 500 |
| Chain | Residue |
| F | ILE151 |
| F | THR152 |
| F | PRO153 |
| F | TRP154 |
| F | LYS178 |
| F | ALA180 |
| F | SER181 |
| F | PRO210 |
| F | GLY211 |
| F | GLY215 |
| F | GLU216 |
| F | PHE229 |
| F | THR230 |
| F | GLY231 |
| F | GLU232 |
| F | THR235 |
| F | ASN332 |
| F | GLN335 |
| F | HOH638 |
| F | HOH717 |
| F | HOH731 |
| F | HOH789 |
| site_id | AC7 |
| Number of Residues | 21 |
| Details | binding site for residue NAP G 500 |
| Chain | Residue |
| G | ILE151 |
| G | THR152 |
| G | PRO153 |
| G | TRP154 |
| G | LYS178 |
| G | ALA180 |
| G | SER181 |
| G | GLY211 |
| G | GLY215 |
| G | PHE229 |
| G | THR230 |
| G | GLY231 |
| G | GLU232 |
| G | THR235 |
| G | ASN332 |
| G | GLN335 |
| G | HOH607 |
| G | HOH635 |
| G | HOH641 |
| G | HOH662 |
| G | HOH805 |
| site_id | AC8 |
| Number of Residues | 28 |
| Details | binding site for residue NAP H 500 |
| Chain | Residue |
| H | ILE151 |
| H | THR152 |
| H | PRO153 |
| H | TRP154 |
| H | LYS178 |
| H | ALA180 |
| H | SER181 |
| H | PRO210 |
| H | GLY211 |
| H | GLY215 |
| H | GLU216 |
| H | PHE229 |
| H | THR230 |
| H | GLY231 |
| H | GLU232 |
| H | THR235 |
| H | ASN332 |
| H | GLN335 |
| H | HOH612 |
| H | HOH622 |
| H | HOH659 |
| H | HOH670 |
| H | HOH753 |
| H | HOH762 |
| H | HOH774 |
| H | HOH818 |
| H | HOH845 |
| H | HOH862 |
