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5EJC

Crystal structural of the TSC1-TBC1D7 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0005096molecular_functionGTPase activator activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005764cellular_componentlysosome
A0005765cellular_componentlysosomal membrane
A0005829cellular_componentcytosol
A0009267biological_processcellular response to starvation
A0016020cellular_componentmembrane
A0031267molecular_functionsmall GTPase binding
A0031398biological_processpositive regulation of protein ubiquitination
A0031410cellular_componentcytoplasmic vesicle
A0032007biological_processnegative regulation of TOR signaling
A0033596cellular_componentTSC1-TSC2 complex
A0036064cellular_componentciliary basal body
A0043547biological_processpositive regulation of GTPase activity
A0062078molecular_functionTSC1-TSC2 complex binding
A0070848biological_processresponse to growth factor
A0090630biological_processactivation of GTPase activity
A1902018biological_processnegative regulation of cilium assembly
A1904262biological_processnegative regulation of TORC1 signaling
B0005096molecular_functionGTPase activator activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005764cellular_componentlysosome
B0005765cellular_componentlysosomal membrane
B0005829cellular_componentcytosol
B0009267biological_processcellular response to starvation
B0016020cellular_componentmembrane
B0031267molecular_functionsmall GTPase binding
B0031398biological_processpositive regulation of protein ubiquitination
B0031410cellular_componentcytoplasmic vesicle
B0032007biological_processnegative regulation of TOR signaling
B0033596cellular_componentTSC1-TSC2 complex
B0036064cellular_componentciliary basal body
B0043547biological_processpositive regulation of GTPase activity
B0062078molecular_functionTSC1-TSC2 complex binding
B0070848biological_processresponse to growth factor
B0090630biological_processactivation of GTPase activity
B1902018biological_processnegative regulation of cilium assembly
B1904262biological_processnegative regulation of TORC1 signaling

238268

PDB entries from 2025-07-02

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