5EJ2

Crystal structure of Carveol dehydrogenase from Mycobacterium avium in complex with NAD

Replaces:  3UWR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0033702	molecular_function	(+)-trans-carveol dehydrogenase activity
B	0000166	molecular_function	nucleotide binding
B	0016491	molecular_function	oxidoreductase activity
B	0033702	molecular_function	(+)-trans-carveol dehydrogenase activity
C	0000166	molecular_function	nucleotide binding
C	0016491	molecular_function	oxidoreductase activity
C	0033702	molecular_function	(+)-trans-carveol dehydrogenase activity
D	0000166	molecular_function	nucleotide binding
D	0016491	molecular_function	oxidoreductase activity
D	0033702	molecular_function	(+)-trans-carveol dehydrogenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	33
Details	binding site for residue NAD A 300

Chain	Residue
A	GLY22
A	ASP84
A	VAL85
A	ASN111
A	ALA112
A	GLY113
A	VAL114
A	ILE135
A	THR163
A	SER164
A	SER165
A	ARG25
A	TYR178
A	LYS182
A	PRO208
A	THR209
A	GLN210
A	VAL211
A	THR213
A	MET215
A	VAL216
A	HOH403
A	GLY26
A	HOH405
A	HOH425
A	HOH464
A	HOH494
A	GLN27
A	ASP46
A	ILE47
A	ILE51
A	SER59
A	VAL83

---

site_id	AC2
Number of Residues	5
Details	binding site for residue PO4 A 301

Chain	Residue
A	ARG169
A	ARG190
A	HOH462
B	ARG169
B	ARG190

---

site_id	AC3
Number of Residues	2
Details	binding site for residue MPD A 302

Chain	Residue
A	TYR172
A	PRO173

---

site_id	AC4
Number of Residues	33
Details	binding site for residue NAD B 301

Chain	Residue
B	GLY22
B	ARG25
B	GLY26
B	GLN27
B	ASP46
B	ILE47
B	ILE51
B	SER59
B	VAL83
B	ASP84
B	VAL85
B	ASN111
B	ALA112
B	GLY113
B	VAL114
B	ILE135
B	THR163
B	SER164
B	SER165
B	TYR178
B	LYS182
B	PRO208
B	THR209
B	GLN210
B	VAL211
B	THR213
B	MET215
B	VAL216
B	HOH407
B	HOH414
B	HOH425
B	HOH468
B	HOH485

---

site_id	AC5
Number of Residues	2
Details	binding site for residue MPD B 302

Chain	Residue
B	TYR172
B	PRO173

---

site_id	AC6
Number of Residues	33
Details	binding site for residue NAD C 301

Chain	Residue
C	VAL211
C	THR213
C	MET215
C	VAL216
C	HOH403
C	HOH411
C	HOH415
C	HOH454
C	HOH470
C	GLY22
C	ARG25
C	GLY26
C	GLN27
C	ASP46
C	ILE47
C	ILE51
C	SER59
C	VAL83
C	ASP84
C	VAL85
C	ASN111
C	ALA112
C	GLY113
C	VAL114
C	ILE135
C	THR163
C	SER164
C	SER165
C	TYR178
C	LYS182
C	PRO208
C	THR209
C	GLN210

---

site_id	AC7
Number of Residues	2
Details	binding site for residue MPD C 302

Chain	Residue
C	TYR172
C	PRO173

---

site_id	AC8
Number of Residues	5
Details	binding site for residue PO4 C 303

Chain	Residue
C	ARG169
C	ARG190
C	HOH402
D	ARG169
D	ARG190

---

site_id	AC9
Number of Residues	33
Details	binding site for residue NAD D 301

Chain	Residue
D	GLY22
D	ARG25
D	GLY26
D	GLN27
D	ASP46
D	ILE47
D	ILE51
D	SER59
D	VAL83
D	ASP84
D	VAL85
D	ASN111
D	ALA112
D	GLY113
D	VAL114
D	ILE135
D	THR163
D	SER164
D	SER165
D	TYR178
D	LYS182
D	PRO208
D	THR209
D	GLN210
D	VAL211
D	THR213
D	MET215
D	VAL216
D	HOH402
D	HOH418
D	HOH429
D	HOH431
D	HOH442

---

site_id	AD1
Number of Residues	2
Details	binding site for residue MPD D 302

Chain	Residue
D	TYR172
D	PRO173

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