Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
A | 0006470 | biological_process | protein dephosphorylation |
A | 0016311 | biological_process | dephosphorylation |
B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
B | 0006470 | biological_process | protein dephosphorylation |
B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | binding site for residue 5OA A 601 |
Chain | Residue |
A | ARG111 |
A | GLN257 |
A | PRO491 |
A | LYS492 |
A | GLN495 |
A | PHE113 |
A | HIS114 |
A | THR218 |
A | THR219 |
A | GLU249 |
A | GLU250 |
A | THR253 |
A | LEU254 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue PO4 A 602 |
Chain | Residue |
A | TYR62 |
A | LYS70 |
A | TYR279 |
A | LYS364 |
A | LYS366 |
A | HOH764 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue PO4 A 603 |
Chain | Residue |
A | ARG111 |
A | GLU195 |
A | LYS198 |
A | GLN257 |
A | LYS260 |
A | HOH736 |
A | HOH772 |
A | HOH788 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue PO4 A 604 |
Chain | Residue |
A | ASN217 |
A | ARG220 |
A | LYS492 |
A | HOH758 |
A | HOH792 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue PO4 A 605 |
Chain | Residue |
A | ARG32 |
A | SER34 |
A | LYS35 |
A | SER36 |
A | THR42 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue PO4 A 606 |
Chain | Residue |
A | ARG138 |
A | SER140 |
A | SER142 |
A | VAL148 |
A | MET171 |
site_id | AC7 |
Number of Residues | 14 |
Details | binding site for residue 5OA B 601 |
Chain | Residue |
B | ARG111 |
B | PHE113 |
B | HIS114 |
B | THR218 |
B | THR219 |
B | GLU249 |
B | GLU250 |
B | THR253 |
B | LEU254 |
B | GLN257 |
B | PRO491 |
B | LYS492 |
B | GLN495 |
B | HOH836 |
site_id | AC8 |
Number of Residues | 7 |
Details | binding site for residue PO4 B 602 |
Chain | Residue |
B | ARG32 |
B | SER34 |
B | LYS35 |
B | SER36 |
B | THR42 |
B | MET311 |
B | HOH793 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue PO4 B 603 |
Chain | Residue |
B | TYR62 |
B | LYS70 |
B | TYR279 |
B | LYS364 |
B | LYS366 |
site_id | AD1 |
Number of Residues | 7 |
Details | binding site for residue PO4 B 604 |
Chain | Residue |
B | ARG111 |
B | GLU195 |
B | LYS198 |
B | GLN257 |
B | LYS260 |
B | HOH777 |
B | HOH799 |
Functional Information from PROSITE/UniProt
site_id | PS00383 |
Number of Residues | 11 |
Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
Chain | Residue | Details |
A | VAL457-GLY467 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Phosphocysteine intermediate |
Chain | Residue | Details |
A | CYS459 | |
B | CYS459 | |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | ASP425 | |
A | CYS459 | |
A | GLN506 | |
B | ASP425 | |
B | CYS459 | |
B | GLN506 | |
Chain | Residue | Details |
A | THR2 | |
B | THR2 | |
Chain | Residue | Details |
A | TYR62 | |
B | TYR62 | |
Chain | Residue | Details |
A | TYR66 | |
B | TYR66 | |