5EGW
2.70 A crystal structure of the Amb a 11 cysteine protease, a major ragweed pollen allergen, in its proform
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
A | 0042803 | molecular_function | protein homodimerization activity |
B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0008234 | molecular_function | cysteine-type peptidase activity |
B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PROSITE/UniProt
site_id | PS00139 |
Number of Residues | 12 |
Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGgCGSCWAfAA |
Chain | Residue | Details |
A | GLN149-ALA160 |
site_id | PS00640 |
Number of Residues | 20 |
Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. FWTvKNSWgptWGekGYIhL |
Chain | Residue | Details |
A | PHE305-LEU324 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10088, ECO:0000269|PubMed:27129273 |
Chain | Residue | Details |
A | CYS155 | |
B | CYS155 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10089, ECO:0000305|PubMed:27129273 |
Chain | Residue | Details |
A | HIS289 | |
B | HIS289 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10090, ECO:0000305|PubMed:27129273 |
Chain | Residue | Details |
A | ASN310 | |
B | ASN310 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498, ECO:0000269|PubMed:25865353 |
Chain | Residue | Details |
A | ASN127 | |
B | ASN127 |