5EGV
Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex the 3,4-diaryl-furan derivative 3-chloranyl-4-[4-(2-chloranyl-4-oxidanyl-phenyl)furan-3-yl]phenol
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue 5OS A 900 |
| Chain | Residue |
| A | MET343 |
| A | LEU540 |
| A | LEU346 |
| A | THR347 |
| A | LEU349 |
| A | ALA350 |
| A | GLU353 |
| A | LEU384 |
| A | LEU387 |
| A | MET421 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue 5OS B 900 |
| Chain | Residue |
| B | LEU346 |
| B | THR347 |
| B | GLU353 |
| B | LEU384 |
| B | LEU387 |
| B | MET388 |
| B | LEU540 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| C | SER699 | |
| D | SER699 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS447 | |
| B | CYS447 |
