5EGI
Structure of a Trimeric Intracellular Cation channel from C. elegans with bound Ca2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| B | 0005267 | molecular_function | potassium channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0071805 | biological_process | potassium ion transmembrane transport |
| C | 0005267 | molecular_function | potassium channel activity |
| C | 0016020 | cellular_component | membrane |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0071805 | biological_process | potassium ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue PT5 A 301 |
| Chain | Residue |
| A | GLU41 |
| A | HIS184 |
| A | GLU186 |
| A | PRO190 |
| A | SER191 |
| A | THR194 |
| B | SER60 |
| B | SER64 |
| B | ARG177 |
| A | MET68 |
| A | LYS129 |
| A | ARG133 |
| A | ALA164 |
| A | GLY165 |
| A | SER166 |
| A | GLY167 |
| A | ARG170 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue PT5 B 301 |
| Chain | Residue |
| B | GLU41 |
| B | LEU79 |
| B | LYS129 |
| B | ARG133 |
| B | ALA164 |
| B | SER166 |
| B | GLY167 |
| B | ILE168 |
| B | ARG170 |
| B | HIS184 |
| B | GLU186 |
| B | ALA193 |
| B | THR194 |
| C | LEU63 |
| C | LEU67 |
| C | PHE74 |
| C | ARG177 |
| C | DMU302 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 302 |
| Chain | Residue |
| B | HOH401 |
| B | HOH401 |
| B | HOH402 |
| B | HOH402 |
| C | HOH404 |
| C | HOH404 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue PT5 C 301 |
| Chain | Residue |
| A | LEU67 |
| A | LEU172 |
| C | GLU41 |
| C | MET68 |
| C | PHE78 |
| C | LYS129 |
| C | ARG133 |
| C | THR160 |
| C | ALA164 |
| C | GLY165 |
| C | SER166 |
| C | GLY167 |
| C | ILE168 |
| C | ARG170 |
| C | HIS184 |
| C | PRO190 |
| C | THR194 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue DMU C 302 |
| Chain | Residue |
| B | LEU157 |
| B | THR194 |
| B | VAL198 |
| B | PT5301 |
| C | PHE53 |
| C | HIS57 |
| C | LEU59 |
| C | SER60 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 117 |
| Details | TOPO_DOM: Lumenal => ECO:0000305|PubMed:27698420 |
| Chain | Residue | Details |
| A | MET1-TYR27 | |
| C | GLY81-LYS89 | |
| C | PRO149-ASN150 | |
| C | THR211-ALA215 | |
| A | GLY81-LYS89 | |
| A | PRO149-ASN150 | |
| A | THR211-ALA215 | |
| B | MET1-TYR27 | |
| B | GLY81-LYS89 | |
| B | PRO149-ASN150 | |
| B | THR211-ALA215 | |
| C | MET1-TYR27 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 51 |
| Details | TRANSMEM: Helical;Name=1 => ECO:0000269|PubMed:27698420 |
| Chain | Residue | Details |
| A | PRO28-ASP45 | |
| B | PRO28-ASP45 | |
| C | PRO28-ASP45 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 93 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:27698420 |
| Chain | Residue | Details |
| A | LEU46-LYS56 | |
| A | PRO108-THR119 | |
| A | GLY178-LEU188 | |
| B | LEU46-LYS56 | |
| B | PRO108-THR119 | |
| B | GLY178-LEU188 | |
| C | LEU46-LYS56 | |
| C | PRO108-THR119 | |
| C | GLY178-LEU188 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 69 |
| Details | TRANSMEM: Discontinuously helical;Name=2 => ECO:0000269|PubMed:27698420 |
| Chain | Residue | Details |
| A | HIS57-LEU80 | |
| B | HIS57-LEU80 | |
| C | HIS57-LEU80 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 51 |
| Details | TRANSMEM: Helical;Name=3 => ECO:0000269|PubMed:27698420 |
| Chain | Residue | Details |
| A | ARG90-ALA107 | |
| B | ARG90-ALA107 | |
| C | ARG90-ALA107 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical;Name=4 => ECO:0000269|PubMed:27698420 |
| Chain | Residue | Details |
| A | PRO120-TYR148 | |
| B | PRO120-TYR148 | |
| C | PRO120-TYR148 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 78 |
| Details | TRANSMEM: Discontinuously helical;Name=5 => ECO:0000269|PubMed:27698420 |
| Chain | Residue | Details |
| A | SER151-ARG177 | |
| B | SER151-ARG177 | |
| C | SER151-ARG177 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 63 |
| Details | TRANSMEM: Helical;Name=6 => ECO:0000269|PubMed:27698420 |
| Chain | Residue | Details |
| A | ARG189-GLY210 | |
| B | ARG189-GLY210 | |
| C | ARG189-GLY210 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 69 |
| Details | TRANSMEM: Helical;Name=7 => ECO:0000269|PubMed:27698420 |
| Chain | Residue | Details |
| A | PRO216-HIS239 | |
| B | PRO216-HIS239 | |
| C | PRO216-HIS239 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27698420, ECO:0007744|PDB:5EGI |
| Chain | Residue | Details |
| A | LYS129 | |
| A | ARG133 | |
| B | LYS129 | |
| B | ARG133 | |
| C | LYS129 | |
| C | ARG133 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0007744|PDB:5EGI |
| Chain | Residue | Details |
| A | SER166 | |
| B | SER166 | |
| C | SER166 |
