5EG6

CSL-RITA complex bound to DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
C	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0005634	cellular_component	nucleus
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006357	biological_process	regulation of transcription by RNA polymerase II

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue EDO C 501

Chain	Residue
C	THR469
C	TYR470
C	THR471

---

site_id	AC2
Number of Residues	4
Details	binding site for residue EDO C 502

Chain	Residue
C	LYS212
C	THR359
C	ASP360
C	LYS361

---

site_id	AC3
Number of Residues	5
Details	binding site for residue EDO C 503

Chain	Residue
C	ASP254
C	GLU255
C	ARG264
C	ASP252
C	ASP254

---

site_id	AC4
Number of Residues	8
Details	binding site for residue EDO C 504

Chain	Residue
C	ARG69
C	PRO451
C	VAL452
C	THR464
C	SER465
C	LEU466
C	THR467
C	HOH668

---

site_id	AC5
Number of Residues	6
Details	binding site for residue EDO C 505

Chain	Residue
C	ARG69
C	ASP71
C	GLY103
C	SER104
C	HOH643
C	HOH731

---

site_id	AC6
Number of Residues	6
Details	binding site for residue EDO C 506

Chain	Residue
C	LYS108
C	GLU111
C	GLN112
C	ARG115
C	HOH619
C	HOH716

---

site_id	AC7
Number of Residues	3
Details	binding site for residue EDO C 507

Chain	Residue
C	LYS185
C	ARG186
C	HOH706

---

site_id	AC8
Number of Residues	1
Details	binding site for residue EDO C 508

Chain	Residue
C	VAL224

---

site_id	AC9
Number of Residues	5
Details	binding site for residue EDO C 509

Chain	Residue
C	LEU57
C	THR58
C	GLU416
C	EDO517
C	HOH613

---

site_id	AD1
Number of Residues	6
Details	binding site for residue EDO C 510

Chain	Residue
C	VAL181
C	LEU183
C	TYR364
C	VAL380
C	HOH642
C	HOH741

---

site_id	AD2
Number of Residues	3
Details	binding site for residue EDO C 511

Chain	Residue
C	ARG227
C	SER240
C	GLU329

---

site_id	AD3
Number of Residues	6
Details	binding site for residue EDO C 512

Chain	Residue
C	LEU250
C	ASP265
C	GLY266
C	TYR267
C	HIS269
C	GLN272

---

site_id	AD4
Number of Residues	10
Details	binding site for residue EDO C 513

Chain	Residue
C	ARG56
C	ASN407
C	ARG409
C	TRP411
C	GLU416
C	VAL455
C	ARG456
C	ASN457
C	HOH652
C	HOH671

---

site_id	AD5
Number of Residues	6
Details	binding site for residue EDO C 514

Chain	Residue
C	PHE236
C	HIS237
C	ARG330
C	ILE331
C	HOH707
R	TRP945

---

site_id	AD6
Number of Residues	5
Details	binding site for residue EDO C 515

Chain	Residue
C	ASN142
C	LYS146
C	CYS149
C	THR150
C	HOH719

---

site_id	AD7
Number of Residues	5
Details	binding site for residue EDO C 516

Chain	Residue
C	GLY103
C	SER104
C	TRP106
C	LYS107
C	BU1520

---

site_id	AD8
Number of Residues	4
Details	binding site for residue EDO C 517

Chain	Residue
C	THR58
C	ARG59
C	GLU60
C	EDO509

---

site_id	AD9
Number of Residues	4
Details	binding site for residue EDO C 518

Chain	Residue
C	GLY87
C	ASN88
C	GLU89
C	TYR155

---

site_id	AE1
Number of Residues	7
Details	binding site for residue BU1 C 519

Chain	Residue
C	GLN72
C	GLY105
C	LYS108
C	LYS109
C	TYR367
C	GLU368
C	HOH627

---

site_id	AE2
Number of Residues	7
Details	binding site for residue BU1 C 520

Chain	Residue
C	GLN124
C	LEU143
C	LYS146
C	ASN147
C	EDO516
C	LEU101
C	TRP106

---

site_id	AE3
Number of Residues	4
Details	binding site for residue BU1 C 521

Chain	Residue
C	ILE131
C	TYR155
C	SER157
C	HOH602

---

site_id	AE4
Number of Residues	4
Details	binding site for residue BU1 C 522

Chain	Residue
C	GLU363
C	THR365
C	TYR462
C	SER463

---

site_id	AE5
Number of Residues	7
Details	binding site for residue BU1 C 523

Chain	Residue
C	LYS80
C	ASP204
C	THR211
C	GLN308
C	SER358
C	HOH633
C	HOH691

---

site_id	AE6
Number of Residues	3
Details	binding site for residue BU1 C 524

Chain	Residue
C	ARG56
C	THR58
C	MET370

---

site_id	AE7
Number of Residues	3
Details	binding site for residue BU1 C 525

Chain	Residue
C	LEU77
C	MET102
C	VAL280

---

site_id	AE8
Number of Residues	2
Details	binding site for residue EDO R 1001

Chain	Residue
R	LEU944
R	THR946

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Region: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"18381292","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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