Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0000978 | molecular_function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| C | 0001228 | molecular_function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 501 |
| Chain | Residue |
| C | THR469 |
| C | TYR470 |
| C | THR471 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 502 |
| Chain | Residue |
| C | LYS212 |
| C | THR359 |
| C | ASP360 |
| C | LYS361 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| C | ASP254 |
| C | GLU255 |
| C | ARG264 |
| C | ASP252 |
| C | ASP254 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 504 |
| Chain | Residue |
| C | ARG69 |
| C | PRO451 |
| C | VAL452 |
| C | THR464 |
| C | SER465 |
| C | LEU466 |
| C | THR467 |
| C | HOH668 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 505 |
| Chain | Residue |
| C | ARG69 |
| C | ASP71 |
| C | GLY103 |
| C | SER104 |
| C | HOH643 |
| C | HOH731 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 506 |
| Chain | Residue |
| C | LYS108 |
| C | GLU111 |
| C | GLN112 |
| C | ARG115 |
| C | HOH619 |
| C | HOH716 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 507 |
| Chain | Residue |
| C | LYS185 |
| C | ARG186 |
| C | HOH706 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue EDO C 508 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 509 |
| Chain | Residue |
| C | LEU57 |
| C | THR58 |
| C | GLU416 |
| C | EDO517 |
| C | HOH613 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 510 |
| Chain | Residue |
| C | VAL181 |
| C | LEU183 |
| C | TYR364 |
| C | VAL380 |
| C | HOH642 |
| C | HOH741 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 511 |
| Chain | Residue |
| C | ARG227 |
| C | SER240 |
| C | GLU329 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 512 |
| Chain | Residue |
| C | LEU250 |
| C | ASP265 |
| C | GLY266 |
| C | TYR267 |
| C | HIS269 |
| C | GLN272 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue EDO C 513 |
| Chain | Residue |
| C | ARG56 |
| C | ASN407 |
| C | ARG409 |
| C | TRP411 |
| C | GLU416 |
| C | VAL455 |
| C | ARG456 |
| C | ASN457 |
| C | HOH652 |
| C | HOH671 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 514 |
| Chain | Residue |
| C | PHE236 |
| C | HIS237 |
| C | ARG330 |
| C | ILE331 |
| C | HOH707 |
| R | TRP945 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 515 |
| Chain | Residue |
| C | ASN142 |
| C | LYS146 |
| C | CYS149 |
| C | THR150 |
| C | HOH719 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 516 |
| Chain | Residue |
| C | GLY103 |
| C | SER104 |
| C | TRP106 |
| C | LYS107 |
| C | BU1520 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 517 |
| Chain | Residue |
| C | THR58 |
| C | ARG59 |
| C | GLU60 |
| C | EDO509 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 518 |
| Chain | Residue |
| C | GLY87 |
| C | ASN88 |
| C | GLU89 |
| C | TYR155 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue BU1 C 519 |
| Chain | Residue |
| C | GLN72 |
| C | GLY105 |
| C | LYS108 |
| C | LYS109 |
| C | TYR367 |
| C | GLU368 |
| C | HOH627 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue BU1 C 520 |
| Chain | Residue |
| C | GLN124 |
| C | LEU143 |
| C | LYS146 |
| C | ASN147 |
| C | EDO516 |
| C | LEU101 |
| C | TRP106 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue BU1 C 521 |
| Chain | Residue |
| C | ILE131 |
| C | TYR155 |
| C | SER157 |
| C | HOH602 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue BU1 C 522 |
| Chain | Residue |
| C | GLU363 |
| C | THR365 |
| C | TYR462 |
| C | SER463 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue BU1 C 523 |
| Chain | Residue |
| C | LYS80 |
| C | ASP204 |
| C | THR211 |
| C | GLN308 |
| C | SER358 |
| C | HOH633 |
| C | HOH691 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue BU1 C 524 |
| Chain | Residue |
| C | ARG56 |
| C | THR58 |
| C | MET370 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue BU1 C 525 |
| Chain | Residue |
| C | LEU77 |
| C | MET102 |
| C | VAL280 |
| site_id | AE8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO R 1001 |
| Chain | Residue |
| R | LEU944 |
| R | THR946 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| C | LYS201 | |
