5EFG

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with acetate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000118	cellular_component	histone deacetylase complex
A	0004407	molecular_function	histone deacetylase activity
A	0006325	biological_process	chromatin organization
A	0016575	biological_process	histone deacetylation
D	0000118	cellular_component	histone deacetylase complex
D	0004407	molecular_function	histone deacetylase activity
D	0006325	biological_process	chromatin organization
D	0016575	biological_process	histone deacetylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN D 2001

Chain	Residue
D	ASP612
D	HIS614
D	ASP705
D	ACT2004

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site_id	AC2
Number of Residues	5
Details	binding site for residue K D 2002

Chain	Residue
D	ASP610
D	ASP612
D	HIS614
D	SER633
D	LEU634

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site_id	AC3
Number of Residues	6
Details	binding site for residue K D 2003

Chain	Residue
D	PHE623
D	ASP626
D	VAL629
D	TYR662
D	HOH2112
D	HOH2123

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site_id	AC4
Number of Residues	10
Details	binding site for residue ACT D 2004

Chain	Residue
D	PRO571
D	HIS573
D	HIS574
D	GLY582
D	ASP612
D	HIS614
D	ASP705
D	GLY743
D	TYR745
D	ZN2001

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site_id	AC5
Number of Residues	4
Details	binding site for residue ZN A 2001

Chain	Residue
A	ASP612
A	HIS614
A	ASP705
A	ACT2004

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site_id	AC6
Number of Residues	5
Details	binding site for residue K A 2002

Chain	Residue
A	ASP610
A	ASP612
A	HIS614
A	SER633
A	LEU634

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site_id	AC7
Number of Residues	6
Details	binding site for residue K A 2003

Chain	Residue
A	PHE623
A	ASP626
A	VAL629
A	TYR662
A	HOH2107
A	HOH2136

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site_id	AC8
Number of Residues	10
Details	binding site for residue ACT A 2004

Chain	Residue
A	PRO571
A	HIS573
A	HIS574
A	GLY582
A	ASP612
A	HIS614
A	ASP705
A	GLY743
A	TYR745
A	ZN2001

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