Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| A | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ZXM A 301 |
| Chain | Residue |
| A | MET69 |
| A | GLY236 |
| A | ALA237 |
| A | GLU239 |
| A | ARG243 |
| A | HOH462 |
| A | HOH463 |
| A | HOH522 |
| A | SER70 |
| A | ASP104 |
| A | SER130 |
| A | ASN132 |
| A | GLU166 |
| A | THR167 |
| A | ASN170 |
| A | THR235 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue MA4 A 302 |
| Chain | Residue |
| A | ARG93 |
| A | LYS94 |
| A | ILE95 |
| A | HIS96 |
| A | ARG98 |
| A | ILE221 |
| A | VAL224 |
| A | PRO226 |
| A | ALA247 |
| A | ILE261 |
| A | ILE277 |
| A | ALA278 |
| A | ALA282 |
| A | GLU286 |
| A | MA4303 |
| A | HOH422 |
| A | HOH423 |
| A | HOH440 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue MA4 A 303 |
| Chain | Residue |
| A | SER26 |
| A | ARG98 |
| A | ASP101 |
| A | ARG243 |
| A | GLN275 |
| A | ALA278 |
| A | GLY279 |
| A | ALA282 |
| A | MA4302 |
| A | HOH408 |
| A | HOH491 |
Functional Information from PROSITE/UniProt
| site_id | PS00146 |
| Number of Residues | 16 |
| Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMMSTfKvvlCGAVL |
| Chain | Residue | Details |
| A | PHE66-LEU81 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; acyl-ester intermediate","evidences":[{"source":"UniProtKB","id":"A0A5R8T042","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU10101","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"A0A5R8T042","evidenceCode":"ECO:0000250"}]} |
