5EDN

Structure of HOXB13-DNA(TCG) complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
B	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
B	0003677	molecular_function	DNA binding
B	0006355	biological_process	regulation of DNA-templated transcription
G	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
G	0003677	molecular_function	DNA binding
G	0006355	biological_process	regulation of DNA-templated transcription
J	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
J	0003677	molecular_function	DNA binding
J	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue TRS C 101

Chain	Residue
C	DG13
C	DA14
C	DG15
C	DG16
F	DC4

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Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. ISaaTsLSerQITIWFqNrrvkeK

Chain	Residue	Details
A	ILE249-LYS272

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	236
Details	DNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108

Chain	Residue	Details
A	GLY216-LEU275
B	GLY216-LEU275
G	GLY216-LEU275
J	GLY216-LEU275

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