Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5ECQ

Crystal Structure of FIN219-FIP1 complex with JA, VAL and ATP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0002376	biological_process	immune system process
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005773	cellular_component	vacuole
A	0006952	biological_process	defense response
A	0009585	biological_process	red, far-red light phototransduction
A	0009611	biological_process	response to wounding
A	0009627	biological_process	systemic acquired resistance
A	0009640	biological_process	photomorphogenesis
A	0009694	biological_process	jasmonic acid metabolic process
A	0009753	biological_process	response to jasmonic acid
A	0009864	biological_process	induced systemic resistance, jasmonic acid mediated signaling pathway
A	0010046	biological_process	response to mycotoxin
A	0010119	biological_process	regulation of stomatal movement
A	0010193	biological_process	response to ozone
A	0010224	biological_process	response to UV-B
A	0016597	molecular_function	amino acid binding
A	0016874	molecular_function	ligase activity
A	0016881	molecular_function	acid-amino acid ligase activity
A	0018117	biological_process	protein adenylylation
A	0019899	molecular_function	enzyme binding
A	0031348	biological_process	negative regulation of defense response
A	0045087	biological_process	innate immune response
A	0070566	molecular_function	adenylyltransferase activity
A	0070728	molecular_function	L-leucine binding
A	0071365	biological_process	cellular response to auxin stimulus
A	0080123	molecular_function	jasmonoyl-L-amino acid ligase activity
A	2000030	biological_process	regulation of response to red or far red light
A	2000377	biological_process	regulation of reactive oxygen species metabolic process
B	0004364	molecular_function	glutathione transferase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006749	biological_process	glutathione metabolic process
B	0009407	biological_process	toxin catabolic process
B	0009507	cellular_component	chloroplast
B	0009629	biological_process	response to gravity
B	0009636	biological_process	response to toxic substance
B	0016740	molecular_function	transferase activity
B	0019899	molecular_function	enzyme binding
B	0043295	molecular_function	glutathione binding
B	0048046	cellular_component	apoplast
B	2000030	biological_process	regulation of response to red or far red light
C	0004364	molecular_function	glutathione transferase activity
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0006749	biological_process	glutathione metabolic process
C	0009407	biological_process	toxin catabolic process
C	0009507	cellular_component	chloroplast
C	0009629	biological_process	response to gravity
C	0009636	biological_process	response to toxic substance
C	0016740	molecular_function	transferase activity
C	0019899	molecular_function	enzyme binding
C	0043295	molecular_function	glutathione binding
C	0048046	cellular_component	apoplast
C	2000030	biological_process	regulation of response to red or far red light
D	0000166	molecular_function	nucleotide binding
D	0002376	biological_process	immune system process
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005773	cellular_component	vacuole
D	0006952	biological_process	defense response
D	0009585	biological_process	red, far-red light phototransduction
D	0009611	biological_process	response to wounding
D	0009627	biological_process	systemic acquired resistance
D	0009640	biological_process	photomorphogenesis
D	0009694	biological_process	jasmonic acid metabolic process
D	0009753	biological_process	response to jasmonic acid
D	0009864	biological_process	induced systemic resistance, jasmonic acid mediated signaling pathway
D	0010046	biological_process	response to mycotoxin
D	0010119	biological_process	regulation of stomatal movement
D	0010193	biological_process	response to ozone
D	0010224	biological_process	response to UV-B
D	0016597	molecular_function	amino acid binding
D	0016874	molecular_function	ligase activity
D	0016881	molecular_function	acid-amino acid ligase activity
D	0018117	biological_process	protein adenylylation
D	0019899	molecular_function	enzyme binding
D	0031348	biological_process	negative regulation of defense response
D	0045087	biological_process	innate immune response
D	0070566	molecular_function	adenylyltransferase activity
D	0070728	molecular_function	L-leucine binding
D	0071365	biological_process	cellular response to auxin stimulus
D	0080123	molecular_function	jasmonoyl-L-amino acid ligase activity
D	2000030	biological_process	regulation of response to red or far red light
D	2000377	biological_process	regulation of reactive oxygen species metabolic process
E	0004364	molecular_function	glutathione transferase activity
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005829	cellular_component	cytosol
E	0006749	biological_process	glutathione metabolic process
E	0009407	biological_process	toxin catabolic process
E	0009507	cellular_component	chloroplast
E	0009629	biological_process	response to gravity
E	0009636	biological_process	response to toxic substance
E	0016740	molecular_function	transferase activity
E	0019899	molecular_function	enzyme binding
E	0043295	molecular_function	glutathione binding
E	0048046	cellular_component	apoplast
E	2000030	biological_process	regulation of response to red or far red light
F	0004364	molecular_function	glutathione transferase activity
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005829	cellular_component	cytosol
F	0006749	biological_process	glutathione metabolic process
F	0009407	biological_process	toxin catabolic process
F	0009507	cellular_component	chloroplast
F	0009629	biological_process	response to gravity
F	0009636	biological_process	response to toxic substance
F	0016740	molecular_function	transferase activity
F	0019899	molecular_function	enzyme binding
F	0043295	molecular_function	glutathione binding
F	0048046	cellular_component	apoplast
F	2000030	biological_process	regulation of response to red or far red light

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue JAA A 601

Chain	Residue
A	THR121
A	VAL602
A	ATP603
A	HOH816
A	LEU124
A	PHE125
A	PHE220
A	VAL222
A	HIS328
A	ASP329
A	GLY331
A	TRP336

site_id	AC2
Number of Residues	9
Details	binding site for residue VAL A 602

Chain	Residue
A	ALA165
A	THR166
A	TYR170
A	VAL222
A	LYS530
A	GLU533
A	HIS534
A	JAA601
A	ATP603

site_id	AC3
Number of Residues	23
Details	binding site for residue ATP A 603

Chain	Residue
A	ALA96
A	ILE97
A	SER98
A	ILE111
A	PRO112
A	PHE113
A	LEU117
A	MET118
A	THR121
A	GLY163
A	THR164
A	ALA165
A	ASN168
A	VAL169
A	GLY331
A	SER332
A	SER333
A	GLU334
A	TRP336
A	LYS557
A	JAA601
A	VAL602
A	HOH703

site_id	AC4
Number of Residues	10
Details	binding site for residue GSH B 301

Chain	Residue
B	PHE15
B	ARG18
B	PHE37
B	LYS53
B	ILE54
B	PRO55
B	SER67
B	HOH426
B	HOH473
B	HOH490

site_id	AC5
Number of Residues	8
Details	binding site for residue GSH C 301

Chain	Residue
C	SER13
C	LYS53
C	ILE54
C	SER67
C	HOH415
C	HOH471
C	HOH477
C	HOH529

site_id	AC6
Number of Residues	11
Details	binding site for residue JAA D 601

Chain	Residue
D	THR121
D	LEU124
D	PHE125
D	PHE220
D	VAL222
D	HIS328
D	ASP329
D	GLY331
D	TRP336
D	VAL602
D	ATP603

site_id	AC7
Number of Residues	9
Details	binding site for residue VAL D 602

Chain	Residue
D	ALA165
D	THR166
D	TYR170
D	VAL222
D	LYS530
D	GLU533
D	HIS534
D	JAA601
D	HOH720

site_id	AC8
Number of Residues	23
Details	binding site for residue ATP D 603

Chain	Residue
D	LYS557
D	JAA601
D	HOH702
D	HOH715
D	HOH720
D	HOH902
D	ALA96
D	ILE97
D	SER98
D	PRO112
D	PHE113
D	LEU117
D	MET118
D	THR121
D	GLY163
D	THR164
D	ALA165
D	ASN168
D	VAL169
D	GLY331
D	SER332
D	SER333
D	TRP336

site_id	AC9
Number of Residues	12
Details	binding site for residue GSH E 301

Chain	Residue
E	TYR10
E	SER13
E	PHE15
E	PHE37
E	LYS53
E	ILE54
E	PRO55
E	SER67
E	HOH403
E	HOH415
E	HOH439
E	HOH442

site_id	AD1
Number of Residues	13
Details	binding site for residue GSH F 301

Chain	Residue
F	SER13
F	PHE15
F	PHE37
F	LYS53
F	ILE54
F	PRO55
F	GLU66
F	SER67
F	HOH416
F	HOH419
F	HOH459
F	HOH488
F	HOH506

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28223489","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ECH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22628555","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EPL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28223489","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ECK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22628555","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28223489","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EPL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GZZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28223489","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ECL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	480
Details	Domain: {"description":"GST C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00685","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28223489","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ECH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ECS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)