5EC2

KcsA with V76ester+G77dA mutations

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0006813	biological_process	potassium ion transport
C	0008076	cellular_component	voltage-gated potassium channel complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue F09 A 2001

Chain	Residue
A	ARG57
C	LEU46
C	TRP87
C	VAL91

---

site_id	AC2
Number of Residues	6
Details	binding site for residue DGA C 1001

Chain	Residue
C	LEU90
B	GLU53
C	PRO63
C	VAL84
C	LEU86
C	ARG89

---

site_id	AC3
Number of Residues	8
Details	binding site for residue K C 1002

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	K1003
C	K1003
C	K1003
C	K1003

---

site_id	AC4
Number of Residues	16
Details	binding site for residue K C 1003

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	LHV76
C	LHV76
C	LHV76
C	LHV76
C	K1002
C	K1002
C	K1002
C	K1002
C	K1004
C	K1004
C	K1004
C	K1004

---

site_id	AC5
Number of Residues	16
Details	binding site for residue K C 1004

Chain	Residue
C	LHV76
C	LHV76
C	LHV76
C	LHV76
C	DAL77
C	DAL77
C	DAL77
C	DAL77
C	K1003
C	K1003
C	K1003
C	K1003
C	K1005
C	K1005
C	K1005
C	K1005

---

site_id	AC6
Number of Residues	12
Details	binding site for residue K C 1005

Chain	Residue
C	DAL77
C	DAL77
C	DAL77
C	DAL77
C	TYR78
C	TYR78
C	TYR78
C	TYR78
C	K1004
C	K1004
C	K1004
C	K1004

---

site_id	AC7
Number of Residues	4
Details	binding site for residue K C 1007

Chain	Residue
C	HOH1117
C	HOH1117
C	HOH1117
C	HOH1117

---

site_id	AC8
Number of Residues	18
Details	binding site for Ligand residues LHV C 76 through DAL C 77 bound to THR C 75

Chain	Residue
C	GLU71
C	THR74
C	THR75
C	TYR78
C	TYR78
C	GLY79
C	K1003
C	K1003
C	K1003
C	K1003
C	K1004
C	K1004
C	K1004
C	K1004
C	K1005
C	K1005
C	K1005
C	K1005

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
B	TYR192-HIS198

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Intramembrane: {"description":"Helical; Pore-forming"}

Chain

Residue

Details

---