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5EAG

Saccharomyces cerevisiae CYP51 complexed with the plant pathogen inhibitor Prochloraz

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005506molecular_functioniron ion binding
A0008168molecular_functionmethyltransferase activity
A0016020cellular_componentmembrane
A0016126biological_processsterol biosynthetic process
A0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A0020037molecular_functionheme binding
A0032259biological_processmethylation
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues11
Detailsbinding site for residue 5LU A 601
ChainResidue
ATYR126
APHE384
AHEM602
ATHR130
AILE139
ATYR140
AGLY310
AGLY314
ATHR318
ALEU380
ALEU383

site_idAC2
Number of Residues16
Detailsbinding site for residue HEM A 602
ChainResidue
ATYR126
ATYR140
ALEU147
ALYS151
AGLY315
ATHR318
APRO379
ALEU383
AARG385
APRO462
APHE463
AHIS468
ACYS470
AGLY472
A5LU601
AHOH730

Functional Information from PROSITE/UniProt
site_idPS00086
Number of Residues10
DetailsCYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGgGRHRCIG
ChainResidueDetails
APHE463-GLY472

222624

PDB entries from 2024-07-17

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