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5EAD

Saccharomyces cerevisiae CYP51 complexed with the plant pathogen inhibitor S-desthio-prothioconazole

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005506molecular_functioniron ion binding
A0008168molecular_functionmethyltransferase activity
A0016020cellular_componentmembrane
A0016126biological_processsterol biosynthetic process
A0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A0020037molecular_functionheme binding
A0032259biological_processmethylation
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues21
Detailsbinding site for residue HEM A 601
ChainResidue
APHE113
APRO379
ALEU383
AARG385
APRO462
APHE463
AGLY464
AHIS468
ACYS470
AGLY472
A5L9602
ATYR126
AHOH743
AHOH784
ATYR140
ALEU147
ALYS151
AGLY315
ATHR318
ATHR322
ALEU374

site_idAC2
Number of Residues8
Detailsbinding site for residue 5L9 A 602
ChainResidue
ATYR126
ATYR140
APHE236
AGLY314
ALEU380
ALEU383
AHEM601
AHOH743

Functional Information from PROSITE/UniProt
site_idPS00086
Number of Residues10
DetailsCYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGgGRHRCIG
ChainResidueDetails
APHE463-GLY472

222415

PDB entries from 2024-07-10

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