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5EAB

Saccharomyces cerevisiae CYP51 complexed with the plant pathogen inhibitor S-tebuconazole

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005506molecular_functioniron ion binding
A0005783cellular_componentendoplasmic reticulum
A0006694biological_processsteroid biosynthetic process
A0006696biological_processergosterol biosynthetic process
A0008168molecular_functionmethyltransferase activity
A0008202biological_processsteroid metabolic process
A0016020cellular_componentmembrane
A0016126biological_processsterol biosynthetic process
A0016491molecular_functionoxidoreductase activity
A0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A0020037molecular_functionheme binding
A0032259biological_processmethylation
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues18
Detailsbinding site for residue HEM A 601
ChainResidue
APHE113
ALEU383
AARG385
APRO462
APHE463
AHIS468
ACYS470
AGLY472
AALA476
ATBX602
ATYR126
ATYR140
ALEU147
ALYS151
AGLY315
ATHR318
ALEU374
APRO379

site_idAC2
Number of Residues6
Detailsbinding site for residue TBX A 602
ChainResidue
AILE139
APHE236
AGLY310
AGLY314
ALEU380
AHEM601

Functional Information from PROSITE/UniProt
site_idPS00086
Number of Residues10
DetailsCYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGgGRHRCIG
ChainResidueDetails
APHE463-GLY472

218853

PDB entries from 2024-04-24

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