Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006835 | biological_process | dicarboxylic acid transport |
| A | 0015293 | molecular_function | symporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006835 | biological_process | dicarboxylic acid transport |
| B | 0015293 | molecular_function | symporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006835 | biological_process | dicarboxylic acid transport |
| C | 0015293 | molecular_function | symporter activity |
| C | 0016020 | cellular_component | membrane |
| C | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue ASP A 501 |
| Chain | Residue |
| A | ARG278 |
| A | GLY362 |
| A | ASP398 |
| A | ARG401 |
| A | THR402 |
| A | ASN405 |
| A | SER279 |
| A | SER280 |
| A | THR317 |
| A | ALA356 |
| A | GLY357 |
| A | VAL358 |
| A | GLY360 |
| A | ALA361 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 502 |
| Chain | Residue |
| A | SER280 |
| A | GLY309 |
| A | ALA310 |
| A | ASN313 |
| A | ASN405 |
| A | ASP409 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 503 |
| Chain | Residue |
| A | THR311 |
| A | MET314 |
| A | SER352 |
| A | ILE353 |
| A | THR355 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 504 |
| Chain | Residue |
| A | TYR91 |
| A | THR94 |
| A | SER95 |
| A | ASN313 |
| A | ASP315 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue DMU A 505 |
| Chain | Residue |
| A | LEU198 |
| A | GLY202 |
| A | TYR206 |
| A | ARG289 |
| C | ARG173 |
| C | PEG510 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue 1PE A 506 |
| Chain | Residue |
| A | TYR44 |
| C | VAL133 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE A 507 |
| Chain | Residue |
| A | ARG107 |
| A | LEU108 |
| A | ASN110 |
| A | LYS232 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 508 |
| Chain | Residue |
| A | ILE162 |
| A | PEG509 |
| A | PEG516 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 509 |
| Chain | Residue |
| A | PRO77 |
| A | GLY81 |
| A | PEG508 |
| A | PEG516 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 510 |
| Chain | Residue |
| A | ALA146 |
| A | LYS150 |
| B | ALA149 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 511 |
| Chain | Residue |
| A | GLU183 |
| A | ARG187 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 512 |
| Chain | Residue |
| A | PHE145 |
| A | PHE159 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 513 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 514 |
| Chain | Residue |
| B | 1PE507 |
| B | P6G525 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 515 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 516 |
| Chain | Residue |
| A | ILE157 |
| A | PEG508 |
| A | PEG509 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 517 |
| Chain | Residue |
| A | GLU152 |
| A | PGE519 |
| A | PGE520 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue PGE A 518 |
| Chain | Residue |
| A | ILE353 |
| A | GLY354 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue PGE A 519 |
| Chain | Residue |
| A | ILE312 |
| A | PEG517 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue PGE A 520 |
| Chain | Residue |
| A | GLY151 |
| A | SER281 |
| A | ALA356 |
| A | GLY357 |
| A | VAL358 |
| A | PEG517 |
| A | PGE521 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue PGE A 521 |
| Chain | Residue |
| A | ALA149 |
| A | LYS150 |
| A | PGE520 |
| C | ASN143 |
| C | ALA146 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue P6G A 522 |
| Chain | Residue |
| A | VAL226 |
| A | VAL227 |
| A | ALA231 |
| A | GLY235 |
| site_id | AE5 |
| Number of Residues | 15 |
| Details | binding site for residue ASP B 501 |
| Chain | Residue |
| B | THR402 |
| B | ASN405 |
| B | ARG278 |
| B | SER279 |
| B | SER280 |
| B | THR317 |
| B | THR355 |
| B | ALA356 |
| B | GLY357 |
| B | VAL358 |
| B | GLY360 |
| B | ALA361 |
| B | GLY362 |
| B | ASP398 |
| B | ARG401 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 502 |
| Chain | Residue |
| B | THR311 |
| B | MET314 |
| B | SER352 |
| B | ILE353 |
| B | THR355 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 503 |
| Chain | Residue |
| B | SER280 |
| B | GLY309 |
| B | ALA310 |
| B | ASN313 |
| B | ASN405 |
| B | ASP409 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 504 |
| Chain | Residue |
| B | TYR91 |
| B | THR94 |
| B | SER95 |
| B | ASN313 |
| B | ASP315 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue DMU B 505 |
| Chain | Residue |
| B | LEU198 |
| B | GLY201 |
| B | GLY202 |
| B | GLN205 |
| B | GLU293 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue 1PE B 506 |
| Chain | Residue |
| B | LEU132 |
| B | ILE353 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE B 507 |
| Chain | Residue |
| A | ASP424 |
| A | PEG514 |
| B | ILE162 |
| B | PEG509 |
| site_id | AF3 |
| Number of Residues | 2 |
| Details | binding site for residue 1PE B 508 |
| Chain | Residue |
| B | VAL255 |
| B | PEG522 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 509 |
| Chain | Residue |
| B | PRO77 |
| B | GLY81 |
| B | 1PE507 |
| B | P6G525 |
| site_id | AF5 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 510 |
| Chain | Residue |
| B | MET219 |
| B | PEG521 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 512 |
| Chain | Residue |
| B | ARG107 |
| B | LEU338 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 513 |
| Chain | Residue |
| B | LEU22 |
| B | PHE275 |
| B | MET403 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 515 |
| Chain | Residue |
| B | ASN172 |
| B | ASN174 |
| B | ARG179 |
| site_id | AF9 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 516 |
| Chain | Residue |
| B | PHE145 |
| B | PHE159 |
| site_id | AG1 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 517 |
| Chain | Residue |
| B | PEG518 |
| C | ASN174 |
| site_id | AG2 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 518 |
| Chain | Residue |
| B | LEU252 |
| B | PEG517 |
| site_id | AG3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 519 |
| Chain | Residue |
| B | GLY122 |
| B | LYS123 |
| B | GLY374 |
| B | ASP376 |
| site_id | AG4 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 520 |
| Chain | Residue |
| B | VAL227 |
| B | PEG521 |
| site_id | AG5 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 521 |
| Chain | Residue |
| B | VAL226 |
| B | PEG510 |
| B | PEG520 |
| site_id | AG6 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 522 |
| Chain | Residue |
| B | GLY257 |
| B | LYS418 |
| B | 1PE508 |
| site_id | AG7 |
| Number of Residues | 2 |
| Details | binding site for residue PGE B 523 |
| Chain | Residue |
| B | ARG107 |
| B | LEU108 |
| site_id | AG8 |
| Number of Residues | 8 |
| Details | binding site for residue P6G B 524 |
| Chain | Residue |
| B | THR135 |
| B | ILE139 |
| B | GLY151 |
| B | SER281 |
| B | THR311 |
| B | ILE312 |
| B | ALA356 |
| B | GLY357 |
| site_id | AG9 |
| Number of Residues | 4 |
| Details | binding site for residue P6G B 525 |
| Chain | Residue |
| A | PEG514 |
| B | GLY84 |
| B | VAL88 |
| B | PEG509 |
| site_id | AH1 |
| Number of Residues | 14 |
| Details | binding site for residue ASP C 501 |
| Chain | Residue |
| C | ARG278 |
| C | SER279 |
| C | SER280 |
| C | THR317 |
| C | THR355 |
| C | ALA356 |
| C | GLY357 |
| C | VAL358 |
| C | PRO359 |
| C | GLY362 |
| C | ASP398 |
| C | ARG401 |
| C | THR402 |
| C | ASN405 |
| site_id | AH2 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 502 |
| Chain | Residue |
| C | GLY309 |
| C | ALA310 |
| C | ASN313 |
| C | ASN405 |
| C | ASP409 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 503 |
| Chain | Residue |
| C | THR311 |
| C | MET314 |
| C | SER352 |
| C | ILE353 |
| C | THR355 |
| site_id | AH4 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 504 |
| Chain | Residue |
| C | TYR91 |
| C | THR94 |
| C | SER95 |
| C | ASN313 |
| C | ASP315 |
| site_id | AH5 |
| Number of Residues | 7 |
| Details | binding site for residue DMU C 505 |
| Chain | Residue |
| C | TYR9 |
| C | LEU198 |
| C | GLY202 |
| C | GLN205 |
| C | ILE209 |
| C | ARG289 |
| C | GLU293 |
| site_id | AH6 |
| Number of Residues | 1 |
| Details | binding site for residue 1PE C 506 |
| site_id | AH7 |
| Number of Residues | 1 |
| Details | binding site for residue 1PE C 507 |
| site_id | AH8 |
| Number of Residues | 2 |
| Details | binding site for residue PEG C 508 |
| Chain | Residue |
| C | PEG509 |
| C | PEG516 |
| site_id | AH9 |
| Number of Residues | 4 |
| Details | binding site for residue PEG C 509 |
| Chain | Residue |
| C | ILE162 |
| C | ILE165 |
| C | TYR169 |
| C | PEG508 |
| site_id | AI1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG C 510 |
| Chain | Residue |
| A | LEU198 |
| A | DMU505 |
| C | ILE165 |
| site_id | AI2 |
| Number of Residues | 1 |
| Details | binding site for residue PEG C 511 |
| site_id | AI3 |
| Number of Residues | 2 |
| Details | binding site for residue PEG C 512 |
| Chain | Residue |
| C | LEU186 |
| C | ARG187 |
| site_id | AI4 |
| Number of Residues | 1 |
| Details | binding site for residue PEG C 513 |
| site_id | AI5 |
| Number of Residues | 2 |
| Details | binding site for residue PEG C 514 |
| Chain | Residue |
| C | LEU252 |
| C | PHE256 |
| site_id | AI6 |
| Number of Residues | 4 |
| Details | binding site for residue PEG C 515 |
| Chain | Residue |
| C | ARG107 |
| C | LEU336 |
| C | LEU338 |
| C | GLN341 |
| site_id | AI7 |
| Number of Residues | 1 |
| Details | binding site for residue PEG C 516 |
| site_id | AI8 |
| Number of Residues | 6 |
| Details | binding site for residue PGE C 517 |
| Chain | Residue |
| C | LEU22 |
| C | ILE272 |
| C | PHE275 |
| C | MET403 |
| C | PGE518 |
| C | P6G520 |
| site_id | AI9 |
| Number of Residues | 3 |
| Details | binding site for residue PGE C 518 |
| Chain | Residue |
| C | TYR238 |
| C | PGE517 |
| C | P6G520 |
| site_id | AJ1 |
| Number of Residues | 2 |
| Details | binding site for residue P6G C 519 |
| Chain | Residue |
| C | GLY151 |
| C | SER281 |
| site_id | AJ2 |
| Number of Residues | 5 |
| Details | binding site for residue P6G C 520 |
| Chain | Residue |
| C | VAL234 |
| C | TYR238 |
| C | THR239 |
| C | PGE517 |
| C | PGE518 |
Functional Information from PROSITE/UniProt
| site_id | PS00713 |
| Number of Residues | 16 |
| Details | NA_DICARBOXYL_SYMP_1 Sodium:dicarboxylate symporter family signature 1. PfGDlFVrLLKMLVmP |
| Chain | Residue | Details |
| A | PRO47-PRO62 | |
