5E94

Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0004930	molecular_function	G protein-coupled receptor activity
G	0004967	molecular_function	glucagon receptor activity
G	0007186	biological_process	G protein-coupled receptor signaling pathway
G	0008528	molecular_function	G protein-coupled peptide receptor activity
G	0016020	cellular_component	membrane
H	0004930	molecular_function	G protein-coupled receptor activity
H	0004967	molecular_function	glucagon receptor activity
H	0007186	biological_process	G protein-coupled receptor signaling pathway
H	0008528	molecular_function	G protein-coupled peptide receptor activity
H	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
A	TYR192-HIS198
B	TYR204-HIS210

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site_id	PS00649
Number of Residues	25
Details	G_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CnrtFDeya.CWpdGepgsfvnvsCP

Chain	Residue	Details
G	CYS62-PRO86

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	230
Details	TOPO_DOM: Extracellular => ECO:0000269|PubMed:28514449

Chain	Residue	Details
G	ARG24-GLU139
H	ARG24-GLU139

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site_id	SWS_FT_FI2
Number of Residues	4
Details	SITE: Interaction with the endogenous ligand GLP-1 => ECO:0000269|PubMed:19861722

Chain	Residue	Details
G	ARG121
G	GLU128
H	ARG121
H	GLU128

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site_id	SWS_FT_FI3
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:22412906

Chain	Residue	Details
G	ASN63
G	ASN82
G	ASN115
H	ASN63
H	ASN82
H	ASN115

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