5E7O
Crystal structure of the perchlorate reductase PcrAB mutant W461E of PcrA from Azospira suillum PS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0030313 | cellular_component | cell envelope |
| A | 0043546 | molecular_function | molybdopterin cofactor binding |
| A | 0045333 | biological_process | cellular respiration |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 1990204 | cellular_component | oxidoreductase complex |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0009061 | biological_process | anaerobic respiration |
| B | 0016020 | cellular_component | membrane |
| B | 0030313 | cellular_component | cell envelope |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| C | 0016020 | cellular_component | membrane |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0030313 | cellular_component | cell envelope |
| C | 0043546 | molecular_function | molybdopterin cofactor binding |
| C | 0045333 | biological_process | cellular respiration |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051536 | molecular_function | iron-sulfur cluster binding |
| C | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| C | 1990204 | cellular_component | oxidoreductase complex |
| D | 0009055 | molecular_function | electron transfer activity |
| D | 0009061 | biological_process | anaerobic respiration |
| D | 0016020 | cellular_component | membrane |
| D | 0030313 | cellular_component | cell envelope |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| D | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| E | 0016020 | cellular_component | membrane |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0030313 | cellular_component | cell envelope |
| E | 0043546 | molecular_function | molybdopterin cofactor binding |
| E | 0045333 | biological_process | cellular respiration |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0051536 | molecular_function | iron-sulfur cluster binding |
| E | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| E | 1990204 | cellular_component | oxidoreductase complex |
| F | 0009055 | molecular_function | electron transfer activity |
| F | 0009061 | biological_process | anaerobic respiration |
| F | 0016020 | cellular_component | membrane |
| F | 0030313 | cellular_component | cell envelope |
| F | 0042597 | cellular_component | periplasmic space |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0051536 | molecular_function | iron-sulfur cluster binding |
| F | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| F | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| G | 0016020 | cellular_component | membrane |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0030313 | cellular_component | cell envelope |
| G | 0043546 | molecular_function | molybdopterin cofactor binding |
| G | 0045333 | biological_process | cellular respiration |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0051536 | molecular_function | iron-sulfur cluster binding |
| G | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| G | 1990204 | cellular_component | oxidoreductase complex |
| H | 0009055 | molecular_function | electron transfer activity |
| H | 0009061 | biological_process | anaerobic respiration |
| H | 0016020 | cellular_component | membrane |
| H | 0030313 | cellular_component | cell envelope |
| H | 0042597 | cellular_component | periplasmic space |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0051536 | molecular_function | iron-sulfur cluster binding |
| H | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| H | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| I | 0016020 | cellular_component | membrane |
| I | 0016491 | molecular_function | oxidoreductase activity |
| I | 0030313 | cellular_component | cell envelope |
| I | 0043546 | molecular_function | molybdopterin cofactor binding |
| I | 0045333 | biological_process | cellular respiration |
| I | 0046872 | molecular_function | metal ion binding |
| I | 0051536 | molecular_function | iron-sulfur cluster binding |
| I | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| I | 1990204 | cellular_component | oxidoreductase complex |
| J | 0009055 | molecular_function | electron transfer activity |
| J | 0009061 | biological_process | anaerobic respiration |
| J | 0016020 | cellular_component | membrane |
| J | 0030313 | cellular_component | cell envelope |
| J | 0042597 | cellular_component | periplasmic space |
| J | 0046872 | molecular_function | metal ion binding |
| J | 0051536 | molecular_function | iron-sulfur cluster binding |
| J | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| J | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| K | 0016020 | cellular_component | membrane |
| K | 0016491 | molecular_function | oxidoreductase activity |
| K | 0030313 | cellular_component | cell envelope |
| K | 0043546 | molecular_function | molybdopterin cofactor binding |
| K | 0045333 | biological_process | cellular respiration |
| K | 0046872 | molecular_function | metal ion binding |
| K | 0051536 | molecular_function | iron-sulfur cluster binding |
| K | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| K | 1990204 | cellular_component | oxidoreductase complex |
| L | 0009055 | molecular_function | electron transfer activity |
| L | 0009061 | biological_process | anaerobic respiration |
| L | 0016020 | cellular_component | membrane |
| L | 0030313 | cellular_component | cell envelope |
| L | 0042597 | cellular_component | periplasmic space |
| L | 0046872 | molecular_function | metal ion binding |
| L | 0051536 | molecular_function | iron-sulfur cluster binding |
| L | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| L | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 A 1001 |
| Chain | Residue |
| A | HIS32 |
| A | CYS36 |
| A | GLY38 |
| A | ALA39 |
| A | CYS40 |
| A | HIS42 |
| A | GLY73 |
| A | CYS74 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MO A 1002 |
| Chain | Residue |
| A | MGD1003 |
| A | MD11004 |
| A | ASP170 |
| site_id | AC3 |
| Number of Residues | 37 |
| Details | binding site for residue MGD A 1003 |
| Chain | Residue |
| A | LYS76 |
| A | ASP170 |
| A | TRP200 |
| A | GLY201 |
| A | SER202 |
| A | ASN203 |
| A | GLN206 |
| A | THR207 |
| A | ARG208 |
| A | ILE228 |
| A | SER229 |
| A | PRO230 |
| A | ASP231 |
| A | ASN233 |
| A | GLY248 |
| A | ASP250 |
| A | GLY421 |
| A | GLY422 |
| A | GLY423 |
| A | TRP427 |
| A | ILE458 |
| A | GLY459 |
| A | ASN761 |
| A | PRO763 |
| A | HIS764 |
| A | SER765 |
| A | ARG766 |
| A | SER768 |
| A | VAL769 |
| A | HIS770 |
| A | ARG830 |
| A | ARG882 |
| A | MO1002 |
| A | MD11004 |
| A | HOH1156 |
| A | HOH1302 |
| A | HOH1349 |
| site_id | AC4 |
| Number of Residues | 33 |
| Details | binding site for residue MD1 A 1004 |
| Chain | Residue |
| A | LEU33 |
| A | ASN35 |
| A | TYR168 |
| A | ASP170 |
| A | HIS426 |
| A | ARG537 |
| A | GLY538 |
| A | ASN539 |
| A | GLN543 |
| A | ILE564 |
| A | ASN565 |
| A | ILE566 |
| A | ARG567 |
| A | ASP569 |
| A | SER581 |
| A | TRP584 |
| A | LYS587 |
| A | ASP615 |
| A | SER762 |
| A | HIS764 |
| A | VAL769 |
| A | HIS770 |
| A | SER771 |
| A | THR772 |
| A | HIS835 |
| A | CYS836 |
| A | GLN849 |
| A | GLN881 |
| A | ARG882 |
| A | MO1002 |
| A | MGD1003 |
| A | HOH1204 |
| A | HOH1211 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1005 |
| Chain | Residue |
| A | TRP242 |
| A | ILE243 |
| A | HIS244 |
| A | ALA402 |
| B | GLY272 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1006 |
| Chain | Residue |
| A | LYS462 |
| A | ALA464 |
| A | HIS596 |
| A | SER597 |
| A | PHE694 |
| A | ASN697 |
| A | HOH1122 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 1007 |
| Chain | Residue |
| A | TRP321 |
| A | GLN324 |
| A | ARG337 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 1008 |
| Chain | Residue |
| A | ILE897 |
| A | HOH1144 |
| A | HOH1153 |
| A | HOH1392 |
| C | TYR491 |
| C | VAL496 |
| C | GLU508 |
| A | LYS802 |
| A | ARG890 |
| A | THR895 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1009 |
| Chain | Residue |
| A | ASN804 |
| A | PRO896 |
| A | ILE897 |
| A | HOH1292 |
| B | THR109 |
| B | PRO110 |
| B | ARG111 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1010 |
| Chain | Residue |
| A | GLU495 |
| A | ASN553 |
| A | HOH1210 |
| E | TRP806 |
| F | ARG103 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| A | TRP806 |
| B | ARG103 |
| B | ARG105 |
| B | HOH556 |
| B | HOH629 |
| B | HOH637 |
| C | GLU495 |
| C | ASN553 |
| site_id | AD3 |
| Number of Residues | 11 |
| Details | binding site for residue F3S B 402 |
| Chain | Residue |
| B | CYS149 |
| B | ASN151 |
| B | ILE154 |
| B | CYS170 |
| B | LYS171 |
| B | GLY172 |
| B | ALA173 |
| B | GLN174 |
| B | ALA175 |
| B | CYS176 |
| B | ALA194 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 B 403 |
| Chain | Residue |
| B | CYS137 |
| B | ASN138 |
| B | CYS140 |
| B | ALA144 |
| B | CYS145 |
| B | CYS180 |
| B | PRO185 |
| B | LYS196 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 B 404 |
| Chain | Residue |
| B | CYS21 |
| B | ILE22 |
| B | CYS24 |
| B | CYS27 |
| B | ARG47 |
| B | CYS216 |
| B | VAL217 |
| B | GLY218 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 B 405 |
| Chain | Residue |
| B | CYS31 |
| B | TRP35 |
| B | ARG47 |
| B | CYS197 |
| B | CYS200 |
| B | PRO210 |
| B | CYS212 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 406 |
| Chain | Residue |
| B | GLY85 |
| B | ILE86 |
| B | PHE88 |
| B | THR109 |
| B | PRO110 |
| B | ARG111 |
| B | SER112 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 C 1001 |
| Chain | Residue |
| C | HIS32 |
| C | VAL34 |
| C | CYS36 |
| C | GLY38 |
| C | CYS40 |
| C | GLY73 |
| C | CYS74 |
| C | GLY77 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue MO C 1002 |
| Chain | Residue |
| C | ASP170 |
| C | MGD1003 |
| C | MD11004 |
| site_id | AE1 |
| Number of Residues | 36 |
| Details | binding site for residue MGD C 1003 |
| Chain | Residue |
| C | ASN35 |
| C | LYS76 |
| C | ASP170 |
| C | GLY201 |
| C | ASN203 |
| C | GLN206 |
| C | THR207 |
| C | ARG208 |
| C | ILE228 |
| C | SER229 |
| C | PRO230 |
| C | ASP231 |
| C | ASN233 |
| C | GLY248 |
| C | ASP250 |
| C | GLY421 |
| C | GLY422 |
| C | GLY423 |
| C | TRP427 |
| C | ILE458 |
| C | GLY459 |
| C | ASN761 |
| C | PRO763 |
| C | HIS764 |
| C | SER765 |
| C | ARG766 |
| C | SER768 |
| C | HIS770 |
| C | ARG830 |
| C | HIS835 |
| C | ARG882 |
| C | MO1002 |
| C | MD11004 |
| C | HOH1268 |
| C | HOH1351 |
| C | HOH1386 |
| site_id | AE2 |
| Number of Residues | 38 |
| Details | binding site for residue MD1 C 1004 |
| Chain | Residue |
| C | LEU33 |
| C | ASN35 |
| C | PRO138 |
| C | TYR168 |
| C | ASP170 |
| C | ARG537 |
| C | GLY538 |
| C | ASN539 |
| C | GLN543 |
| C | LYS545 |
| C | ILE564 |
| C | ASN565 |
| C | ILE566 |
| C | ARG567 |
| C | ASP569 |
| C | SER581 |
| C | TRP584 |
| C | LYS587 |
| C | ASP615 |
| C | SER762 |
| C | HIS764 |
| C | VAL769 |
| C | HIS770 |
| C | SER771 |
| C | THR772 |
| C | HIS835 |
| C | CYS836 |
| C | GLN849 |
| C | GLN881 |
| C | ARG882 |
| C | MO1002 |
| C | MGD1003 |
| C | HOH1202 |
| C | HOH1224 |
| C | HOH1270 |
| C | HOH1289 |
| C | HOH1333 |
| C | HOH1343 |
| site_id | AE3 |
| Number of Residues | 9 |
| Details | binding site for residue EDO C 1005 |
| Chain | Residue |
| C | TRP242 |
| C | HIS244 |
| C | GLY397 |
| C | VAL398 |
| C | THR399 |
| C | HOH1253 |
| D | GLU268 |
| D | GLY272 |
| D | HOH518 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 1006 |
| Chain | Residue |
| C | TYR510 |
| C | SER514 |
| C | THR736 |
| C | LEU861 |
| C | VAL862 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 1007 |
| Chain | Residue |
| C | ASP803 |
| C | ASN804 |
| C | ASP805 |
| C | PRO896 |
| C | SER898 |
| C | HOH1139 |
| D | PRO110 |
| site_id | AE6 |
| Number of Residues | 8 |
| Details | binding site for residue F3S D 401 |
| Chain | Residue |
| D | CYS149 |
| D | CYS170 |
| D | LYS171 |
| D | ALA173 |
| D | GLN174 |
| D | ALA175 |
| D | CYS176 |
| D | ALA194 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue SF4 D 402 |
| Chain | Residue |
| D | CYS137 |
| D | ASN138 |
| D | CYS140 |
| D | CYS145 |
| D | CYS180 |
| D | TYR182 |
| site_id | AE8 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 D 403 |
| Chain | Residue |
| D | CYS21 |
| D | ILE22 |
| D | CYS24 |
| D | GLN25 |
| D | CYS27 |
| D | ARG47 |
| D | VAL49 |
| D | CYS216 |
| D | VAL217 |
| D | GLY218 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 D 404 |
| Chain | Residue |
| D | CYS31 |
| D | ARG47 |
| D | MET136 |
| D | CYS197 |
| D | GLY199 |
| D | CYS200 |
| D | CYS212 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 405 |
| Chain | Residue |
| C | PHE9 |
| C | HOH1116 |
| D | TYR155 |
| D | ARG157 |
| D | GLN159 |
| D | HOH502 |
| site_id | AF2 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 E 1001 |
| Chain | Residue |
| E | HIS32 |
| E | CYS36 |
| E | ALA39 |
| E | CYS40 |
| E | GLY73 |
| E | CYS74 |
| E | GLY77 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue MO E 1002 |
| Chain | Residue |
| E | ASP170 |
| E | MGD1003 |
| E | MD11004 |
| site_id | AF4 |
| Number of Residues | 35 |
| Details | binding site for residue MGD E 1003 |
| Chain | Residue |
| E | LYS76 |
| E | ASP170 |
| E | GLY201 |
| E | ASN203 |
| E | GLN206 |
| E | THR207 |
| E | ARG208 |
| E | ILE228 |
| E | SER229 |
| E | PRO230 |
| E | ASP231 |
| E | ASN233 |
| E | GLY248 |
| E | ASP250 |
| E | GLY421 |
| E | GLY422 |
| E | GLY423 |
| E | TRP427 |
| E | ILE458 |
| E | GLY459 |
| E | ASN761 |
| E | PRO763 |
| E | HIS764 |
| E | SER765 |
| E | ARG766 |
| E | SER768 |
| E | VAL769 |
| E | HIS770 |
| E | ARG830 |
| E | ARG882 |
| E | MO1002 |
| E | MD11004 |
| E | HOH1130 |
| E | HOH1329 |
| E | HOH1336 |
| site_id | AF5 |
| Number of Residues | 33 |
| Details | binding site for residue MD1 E 1004 |
| Chain | Residue |
| E | LEU33 |
| E | ASN35 |
| E | PRO138 |
| E | TYR168 |
| E | ASP170 |
| E | ARG537 |
| E | GLY538 |
| E | ASN539 |
| E | GLN543 |
| E | LYS545 |
| E | ILE564 |
| E | ASN565 |
| E | ILE566 |
| E | ARG567 |
| E | ASP569 |
| E | SER581 |
| E | TRP584 |
| E | LYS587 |
| E | ASP615 |
| E | SER762 |
| E | HIS764 |
| E | VAL769 |
| E | HIS770 |
| E | SER771 |
| E | THR772 |
| E | HIS835 |
| E | GLN849 |
| E | GLN881 |
| E | ARG882 |
| E | MO1002 |
| E | MGD1003 |
| E | HOH1220 |
| E | HOH1353 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO E 1005 |
| Chain | Residue |
| E | LYS462 |
| E | THR593 |
| E | SER594 |
| E | HIS596 |
| E | ASN697 |
| E | TYR708 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL E 1006 |
| Chain | Residue |
| E | LYS273 |
| E | PRO317 |
| E | LYS318 |
| E | ILE347 |
| E | PRO354 |
| E | ARG727 |
| site_id | AF8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO E 1007 |
| Chain | Residue |
| E | PHE9 |
| E | SER12 |
| E | GLU15 |
| E | HOH1146 |
| E | HOH1388 |
| F | TYR155 |
| F | GLN159 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 401 |
| Chain | Residue |
| E | LYS241 |
| F | GLU268 |
| F | GLY272 |
| F | PRO274 |
| F | HOH533 |
| site_id | AG1 |
| Number of Residues | 11 |
| Details | binding site for residue F3S F 402 |
| Chain | Residue |
| F | CYS149 |
| F | PRO150 |
| F | ASN151 |
| F | CYS170 |
| F | LYS171 |
| F | GLY172 |
| F | ALA173 |
| F | GLN174 |
| F | ALA175 |
| F | CYS176 |
| F | ALA194 |
| site_id | AG2 |
| Number of Residues | 6 |
| Details | binding site for residue SF4 F 403 |
| Chain | Residue |
| F | CYS137 |
| F | ASN138 |
| F | CYS140 |
| F | PRO143 |
| F | CYS145 |
| F | CYS180 |
| site_id | AG3 |
| Number of Residues | 6 |
| Details | binding site for residue SF4 F 404 |
| Chain | Residue |
| F | CYS21 |
| F | ILE22 |
| F | CYS24 |
| F | CYS27 |
| F | CYS216 |
| F | GLY218 |
| site_id | AG4 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 F 405 |
| Chain | Residue |
| F | CYS31 |
| F | ARG47 |
| F | MET136 |
| F | CYS197 |
| F | GLY199 |
| F | CYS200 |
| F | CYS212 |
| site_id | AG5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO F 406 |
| Chain | Residue |
| F | GLY85 |
| F | ILE86 |
| F | THR109 |
| F | PRO110 |
| F | ARG111 |
| F | SER112 |
| F | HOH503 |
| site_id | AG6 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 G 1001 |
| Chain | Residue |
| G | HIS32 |
| G | CYS36 |
| G | ALA39 |
| G | CYS40 |
| G | HIS42 |
| G | GLY73 |
| G | CYS74 |
| G | GLY77 |
| site_id | AG7 |
| Number of Residues | 3 |
| Details | binding site for residue MO G 1002 |
| Chain | Residue |
| G | ASP170 |
| G | MGD1003 |
| G | MD11004 |
| site_id | AG8 |
| Number of Residues | 39 |
| Details | binding site for residue MGD G 1003 |
| Chain | Residue |
| G | LYS76 |
| G | ASP170 |
| G | TRP200 |
| G | GLY201 |
| G | ASN203 |
| G | GLN206 |
| G | THR207 |
| G | ARG208 |
| G | ILE228 |
| G | SER229 |
| G | PRO230 |
| G | ASP231 |
| G | ASN233 |
| G | GLY248 |
| G | ASP250 |
| G | GLY421 |
| G | GLY422 |
| G | GLY423 |
| G | TRP427 |
| G | ILE458 |
| G | GLY459 |
| G | ASN761 |
| G | PRO763 |
| G | HIS764 |
| G | SER765 |
| G | ARG766 |
| G | SER768 |
| G | HIS770 |
| G | ARG830 |
| G | HIS835 |
| G | ARG882 |
| G | MO1002 |
| G | MD11004 |
| G | HOH1128 |
| G | HOH1188 |
| G | HOH1218 |
| G | HOH1337 |
| G | HOH1338 |
| G | HOH1339 |
| site_id | AG9 |
| Number of Residues | 33 |
| Details | binding site for residue MD1 G 1004 |
| Chain | Residue |
| G | ASN35 |
| G | TYR168 |
| G | ASP170 |
| G | TYR536 |
| G | ARG537 |
| G | GLY538 |
| G | ASN539 |
| G | GLN543 |
| G | LYS545 |
| G | ILE564 |
| G | ASN565 |
| G | ILE566 |
| G | ARG567 |
| G | ASP569 |
| G | TRP584 |
| G | LYS587 |
| G | ASP615 |
| G | SER762 |
| G | HIS764 |
| G | VAL769 |
| G | HIS770 |
| G | SER771 |
| G | THR772 |
| G | HIS835 |
| G | GLN849 |
| G | GLN881 |
| G | ARG882 |
| G | MO1002 |
| G | MGD1003 |
| G | HOH1133 |
| G | HOH1150 |
| G | HOH1270 |
| G | HOH1308 |
| site_id | AH1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO G 1005 |
| Chain | Residue |
| G | HIS244 |
| G | GLY397 |
| G | VAL398 |
| G | HOH1153 |
| G | HOH1342 |
| H | GLU268 |
| H | GLY272 |
| site_id | AH2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO G 1006 |
| Chain | Residue |
| G | GLU187 |
| G | THR593 |
| G | SER594 |
| G | HIS596 |
| G | SER597 |
| G | ASN697 |
| site_id | AH3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO G 1007 |
| Chain | Residue |
| G | GLY248 |
| G | GLY251 |
| G | VAL432 |
| G | THR746 |
| G | TYR747 |
| G | LYS748 |
| site_id | AH4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO G 1008 |
| Chain | Residue |
| G | LYS802 |
| G | ASP803 |
| G | ASN804 |
| G | ASP805 |
| G | PRO896 |
| G | HOH1239 |
| site_id | AH5 |
| Number of Residues | 10 |
| Details | binding site for residue F3S H 401 |
| Chain | Residue |
| H | CYS149 |
| H | ASN151 |
| H | ILE154 |
| H | CYS170 |
| H | GLY172 |
| H | ALA173 |
| H | GLN174 |
| H | ALA175 |
| H | CYS176 |
| H | ALA194 |
| site_id | AH6 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 H 402 |
| Chain | Residue |
| H | CYS137 |
| H | ASN138 |
| H | CYS140 |
| H | PRO143 |
| H | ALA144 |
| H | CYS145 |
| H | CYS180 |
| H | TYR182 |
| site_id | AH7 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 H 403 |
| Chain | Residue |
| H | CYS21 |
| H | ILE22 |
| H | GLY23 |
| H | CYS24 |
| H | GLN25 |
| H | CYS27 |
| H | ARG47 |
| H | VAL49 |
| H | PRO134 |
| H | CYS216 |
| H | GLY218 |
| site_id | AH8 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 H 404 |
| Chain | Residue |
| H | TYR14 |
| H | CYS31 |
| H | MET136 |
| H | CYS197 |
| H | CYS200 |
| H | PRO210 |
| H | CYS212 |
| site_id | AH9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO H 405 |
| Chain | Residue |
| H | THR109 |
| H | ARG111 |
| H | SER112 |
| H | HOH506 |
| I | GLY527 |
| site_id | AI1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO H 406 |
| Chain | Residue |
| H | LYS156 |
| site_id | AI2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO H 407 |
| Chain | Residue |
| G | ALA894 |
| H | ARG103 |
| H | HOH509 |
| H | HOH554 |
| I | GLU495 |
| I | ASN553 |
| site_id | AI3 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 I 1001 |
| Chain | Residue |
| I | HIS32 |
| I | CYS36 |
| I | GLY38 |
| I | CYS40 |
| I | GLY73 |
| I | CYS74 |
| I | GLY77 |
| site_id | AI4 |
| Number of Residues | 4 |
| Details | binding site for residue MO I 1002 |
| Chain | Residue |
| I | ASP170 |
| I | GLY459 |
| I | MGD1003 |
| I | MD11004 |
| site_id | AI5 |
| Number of Residues | 38 |
| Details | binding site for residue MGD I 1003 |
| Chain | Residue |
| I | ASN35 |
| I | CYS36 |
| I | LYS76 |
| I | ASP170 |
| I | GLY201 |
| I | ASN203 |
| I | THR207 |
| I | ARG208 |
| I | ILE228 |
| I | SER229 |
| I | PRO230 |
| I | ASP231 |
| I | ASN233 |
| I | GLY248 |
| I | ASP250 |
| I | GLY421 |
| I | GLY422 |
| I | GLY423 |
| I | TRP427 |
| I | TYR457 |
| I | ILE458 |
| I | GLY459 |
| I | ASN761 |
| I | PRO763 |
| I | HIS764 |
| I | SER765 |
| I | ARG766 |
| I | SER768 |
| I | HIS770 |
| I | ARG830 |
| I | HIS835 |
| I | ARG882 |
| I | MO1002 |
| I | MD11004 |
| I | HOH1116 |
| I | HOH1266 |
| I | HOH1272 |
| I | HOH1280 |
| site_id | AI6 |
| Number of Residues | 32 |
| Details | binding site for residue MD1 I 1004 |
| Chain | Residue |
| I | LEU33 |
| I | ASN35 |
| I | PRO138 |
| I | TYR168 |
| I | ASP170 |
| I | ARG537 |
| I | GLY538 |
| I | ASN539 |
| I | GLN543 |
| I | LYS545 |
| I | ILE564 |
| I | ASN565 |
| I | ILE566 |
| I | ARG567 |
| I | ASP569 |
| I | SER581 |
| I | TRP584 |
| I | LYS587 |
| I | ASP615 |
| I | SER762 |
| I | HIS764 |
| I | VAL769 |
| I | HIS770 |
| I | SER771 |
| I | THR772 |
| I | HIS835 |
| I | GLN849 |
| I | GLN881 |
| I | MO1002 |
| I | MGD1003 |
| I | HOH1200 |
| I | HOH1270 |
| site_id | AI7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO I 1005 |
| Chain | Residue |
| I | HIS244 |
| I | GLY397 |
| I | VAL398 |
| J | GLU268 |
| site_id | AI8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO I 1006 |
| Chain | Residue |
| I | ASN804 |
| I | PRO896 |
| I | ILE897 |
| I | SER898 |
| I | HOH1114 |
| I | HOH1135 |
| I | HOH1218 |
| J | PRO110 |
| site_id | AI9 |
| Number of Residues | 11 |
| Details | binding site for residue F3S J 401 |
| Chain | Residue |
| J | CYS149 |
| J | PRO150 |
| J | ASN151 |
| J | CYS170 |
| J | LYS171 |
| J | GLY172 |
| J | ALA173 |
| J | GLN174 |
| J | ALA175 |
| J | CYS176 |
| J | ALA194 |
| site_id | AJ1 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 J 402 |
| Chain | Residue |
| J | CYS137 |
| J | ASN138 |
| J | HIS139 |
| J | CYS140 |
| J | ALA144 |
| J | CYS145 |
| J | CYS180 |
| J | TYR182 |
| site_id | AJ2 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 J 403 |
| Chain | Residue |
| J | CYS21 |
| J | ILE22 |
| J | CYS24 |
| J | CYS27 |
| J | VAL49 |
| J | CYS216 |
| J | VAL217 |
| J | GLY218 |
| J | MET221 |
| site_id | AJ3 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 J 404 |
| Chain | Residue |
| J | TYR14 |
| J | CYS31 |
| J | TRP35 |
| J | ARG47 |
| J | MET136 |
| J | CYS197 |
| J | GLY199 |
| J | CYS200 |
| J | PRO210 |
| J | ALA211 |
| J | CYS212 |
| site_id | AJ4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO J 405 |
| Chain | Residue |
| J | ILE82 |
| J | ILE86 |
| J | PHE88 |
| J | PRO108 |
| J | THR109 |
| J | PRO110 |
| J | ARG111 |
| J | SER112 |
| site_id | AJ5 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 K 1001 |
| Chain | Residue |
| K | HIS32 |
| K | CYS36 |
| K | GLY38 |
| K | ALA39 |
| K | CYS40 |
| K | HIS42 |
| K | GLY73 |
| K | CYS74 |
| K | GLY77 |
| site_id | AJ6 |
| Number of Residues | 4 |
| Details | binding site for residue MO K 1002 |
| Chain | Residue |
| K | ASP170 |
| K | GLY459 |
| K | MGD1003 |
| K | MD11004 |
| site_id | AJ7 |
| Number of Residues | 36 |
| Details | binding site for residue MGD K 1003 |
| Chain | Residue |
| K | LYS76 |
| K | ASP170 |
| K | TRP200 |
| K | GLY201 |
| K | ASN203 |
| K | GLN206 |
| K | THR207 |
| K | ARG208 |
| K | ILE228 |
| K | SER229 |
| K | PRO230 |
| K | ASP231 |
| K | ASN233 |
| K | GLY248 |
| K | ASP250 |
| K | GLY421 |
| K | GLY422 |
| K | GLY423 |
| K | TRP427 |
| K | ILE458 |
| K | GLY459 |
| K | ASN761 |
| K | PRO763 |
| K | HIS764 |
| K | SER765 |
| K | SER768 |
| K | VAL769 |
| K | HIS770 |
| K | ARG830 |
| K | HIS835 |
| K | ARG882 |
| K | MO1002 |
| K | MD11004 |
| K | HOH1214 |
| K | HOH1239 |
| K | HOH1242 |
| site_id | AJ8 |
| Number of Residues | 31 |
| Details | binding site for residue MD1 K 1004 |
| Chain | Residue |
| K | LEU33 |
| K | ASN35 |
| K | PRO138 |
| K | TYR168 |
| K | ASP170 |
| K | ARG537 |
| K | GLY538 |
| K | ASN539 |
| K | GLN543 |
| K | ILE564 |
| K | ASN565 |
| K | ILE566 |
| K | ARG567 |
| K | ASP569 |
| K | SER581 |
| K | TRP584 |
| K | LYS587 |
| K | ASP615 |
| K | SER762 |
| K | HIS764 |
| K | VAL769 |
| K | HIS770 |
| K | SER771 |
| K | THR772 |
| K | HIS835 |
| K | GLN849 |
| K | GLN881 |
| K | MO1002 |
| K | MGD1003 |
| K | HOH1125 |
| K | HOH1141 |
| site_id | AJ9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO K 1005 |
| Chain | Residue |
| K | TRP242 |
| K | HIS244 |
| K | VAL398 |
| L | GLU268 |
| site_id | AK1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO K 1006 |
| Chain | Residue |
| K | ASP803 |
| K | ASN804 |
| K | ASP805 |
| K | PRO896 |
| K | SER898 |
| L | PRO110 |
| site_id | AK2 |
| Number of Residues | 11 |
| Details | binding site for residue F3S L 401 |
| Chain | Residue |
| L | CYS149 |
| L | ASN151 |
| L | ILE154 |
| L | CYS170 |
| L | LYS171 |
| L | GLY172 |
| L | ALA173 |
| L | GLN174 |
| L | ALA175 |
| L | CYS176 |
| L | ALA194 |
| site_id | AK3 |
| Number of Residues | 6 |
| Details | binding site for residue SF4 L 402 |
| Chain | Residue |
| L | CYS137 |
| L | ASN138 |
| L | HIS139 |
| L | CYS140 |
| L | CYS145 |
| L | CYS180 |
| site_id | AK4 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 L 403 |
| Chain | Residue |
| L | CYS21 |
| L | ILE22 |
| L | GLY23 |
| L | CYS24 |
| L | GLN25 |
| L | CYS27 |
| L | ARG47 |
| L | CYS216 |
| L | VAL217 |
| L | GLY218 |
| site_id | AK5 |
| Number of Residues | 8 |
| Details | binding site for residue SF4 L 404 |
| Chain | Residue |
| L | CYS31 |
| L | TRP35 |
| L | ARG47 |
| L | MET136 |
| L | CYS197 |
| L | CYS200 |
| L | ALA211 |
| L | CYS212 |
| site_id | AK6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO L 405 |
| Chain | Residue |
| L | GLY85 |
| L | ILE86 |
| L | PHE88 |
| L | THR109 |
| L | PRO110 |
| L | ARG111 |
| L | SER112 |
| site_id | AK7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO L 406 |
| Chain | Residue |
| G | GLU495 |
| G | ASN553 |
| K | TRP806 |
| K | ALA894 |
| L | ARG103 |
| L | ARG105 |
| L | HOH535 |
