5E6Q

Importin alpha binding to XRCC1 NLS peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005737	cellular_component	cytoplasm
B	0006606	biological_process	protein import into nucleus
B	0061608	molecular_function	nuclear import signal receptor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SO4 B 601

Chain	Residue
B	LYS202
B	GLN352
B	LYS388
B	HOH705
B	HOH722
B	HOH730
B	HOH788

---

site_id	AC2
Number of Residues	5
Details	binding site for residue GOL B 602

Chain	Residue
B	GLY335
B	HIS376
B	HOH703
B	ILE332
B	ASP333

---

site_id	AC3
Number of Residues	1
Details	binding site for residue CL B 603

Chain	Residue
B	THR349

---

site_id	AC4
Number of Residues	2
Details	binding site for residue CL B 604

Chain	Residue
B	SER194
B	ALA195

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER241

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
A	THR257

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	SER259

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER266

---