5E5M

Crystal structure of mouse CTLA-4 in complex with nanobody

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane
A	0042129	biological_process	regulation of T cell proliferation
C	0006955	biological_process	immune response
C	0016020	cellular_component	membrane
C	0042129	biological_process	regulation of T cell proliferation
E	0006955	biological_process	immune response
E	0016020	cellular_component	membrane
E	0042129	biological_process	regulation of T cell proliferation
G	0006955	biological_process	immune response
G	0016020	cellular_component	membrane
G	0042129	biological_process	regulation of T cell proliferation

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL A 201

Chain	Residue
A	GLN80
A	GLY81
A	LEU82
A	ASP86
A	TYR90
G	ARG83

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Region: {"description":"Homodimerization","evidences":[{"source":"UniProtKB","id":"P16410","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	20
Details	Region: {"description":"Important for interaction with CD80 and CD86","evidences":[{"source":"UniProtKB","id":"P16410","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	12
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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