5E3I
Crystal Structure of a Histidyl-tRNA synthetase from Acinetobacter baumannii with bound L-Histidine and ATP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004821 | molecular_function | histidine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
| A | 0140101 | molecular_function | catalytic activity, acting on a tRNA |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004821 | molecular_function | histidine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| B | 0016874 | molecular_function | ligase activity |
| B | 0140101 | molecular_function | catalytic activity, acting on a tRNA |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 500 |
| Chain | Residue |
| A | ATP501 |
| A | HOH627 |
| A | HOH639 |
| A | HOH663 |
| A | HOH731 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue ATP A 501 |
| Chain | Residue |
| A | TYR124 |
| A | PHE127 |
| A | GLN129 |
| A | ARG261 |
| A | THR283 |
| A | VAL284 |
| A | GLY313 |
| A | ARG316 |
| A | MG500 |
| A | HIS502 |
| A | HOH639 |
| A | HOH663 |
| A | HOH666 |
| A | HOH718 |
| A | HOH731 |
| A | HOH765 |
| A | ARG115 |
| A | GLU117 |
| A | GLY122 |
| A | ARG123 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue HIS A 502 |
| Chain | Residue |
| A | GLU85 |
| A | THR87 |
| A | ARG115 |
| A | GLN129 |
| A | GLU133 |
| A | TYR265 |
| A | TYR266 |
| A | ALA286 |
| A | TYR290 |
| A | GLY309 |
| A | PHE310 |
| A | ALA311 |
| A | ATP501 |
| A | HOH611 |
| A | HOH670 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 500 |
| Chain | Residue |
| B | ATP501 |
| B | HOH608 |
| B | HOH634 |
| B | HOH643 |
| B | HOH698 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | binding site for residue ATP B 501 |
| Chain | Residue |
| B | ARG115 |
| B | GLU117 |
| B | GLY122 |
| B | ARG123 |
| B | TYR124 |
| B | PHE127 |
| B | GLN129 |
| B | ARG261 |
| B | THR283 |
| B | VAL284 |
| B | GLY313 |
| B | ARG316 |
| B | MG500 |
| B | HIS502 |
| B | HOH628 |
| B | HOH634 |
| B | HOH643 |
| B | HOH680 |
| B | HOH698 |
| B | HOH769 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for residue HIS B 502 |
| Chain | Residue |
| B | GLU85 |
| B | THR87 |
| B | ARG115 |
| B | GLN129 |
| B | GLU133 |
| B | TYR265 |
| B | TYR266 |
| B | ALA286 |
| B | TYR290 |
| B | GLY309 |
| B | PHE310 |
| B | ATP501 |
| B | HOH623 |
| B | HOH661 |
