5E2H

Crystal Structure of D-alanine Carboxypeptidase AmpC from Mycobacterium smegmatis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0046677	biological_process	response to antibiotic
B	0008800	molecular_function	beta-lactamase activity
B	0016787	molecular_function	hydrolase activity
B	0017001	biological_process	antibiotic catabolic process
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0046677	biological_process	response to antibiotic
C	0008800	molecular_function	beta-lactamase activity
C	0016787	molecular_function	hydrolase activity
C	0017001	biological_process	antibiotic catabolic process
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL A 401

Chain	Residue
A	VAL185
A	ARG243

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site_id	AC2
Number of Residues	3
Details	binding site for residue CL A 402

Chain	Residue
A	GLN114
A	PHE115
A	HOH550

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site_id	AC3
Number of Residues	1
Details	binding site for residue CL B 401

Chain	Residue
B	VAL185

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site_id	AC4
Number of Residues	3
Details	binding site for residue CL B 402

Chain	Residue
B	GLN114
B	PHE115
B	HOH529

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site_id	AC5
Number of Residues	1
Details	binding site for residue CL C 401

Chain	Residue
C	VAL185

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site_id	AC6
Number of Residues	4
Details	binding site for residue CL C 402

Chain	Residue
C	GLN114
C	PHE115
C	HOH549
C	HOH640

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site_id	AC7
Number of Residues	7
Details	binding site for residue GOL C 403

Chain	Residue
C	PHE211
C	ASP212
C	ALA213
C	GLU214
C	HOH502
C	HOH603
C	HOH644

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Functional Information from PROSITE/UniProt

site_id	PS00336
Number of Residues	8
Details	BETA_LACTAMASE_C Beta-lactamase class-C active site. FEIGSVSK

Chain	Residue	Details
A	PHE54-LYS61

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