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5DZK

Crystal structure of the active form of the proteolytic complex clpP1 and clpP2

Functional Information from GO Data
ChainGOidnamespacecontents
A0004176molecular_functionATP-dependent peptidase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006508biological_processproteolysis
A0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
A0008236molecular_functionserine-type peptidase activity
A0009274cellular_componentpeptidoglycan-based cell wall
A0009368cellular_componentendopeptidase Clp complex
A0051117molecular_functionATPase binding
B0004176molecular_functionATP-dependent peptidase activity
B0004252molecular_functionserine-type endopeptidase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006508biological_processproteolysis
B0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
B0008236molecular_functionserine-type peptidase activity
B0009274cellular_componentpeptidoglycan-based cell wall
B0009368cellular_componentendopeptidase Clp complex
B0051117molecular_functionATPase binding
C0004176molecular_functionATP-dependent peptidase activity
C0004252molecular_functionserine-type endopeptidase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0006508biological_processproteolysis
C0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
C0008236molecular_functionserine-type peptidase activity
C0009274cellular_componentpeptidoglycan-based cell wall
C0009368cellular_componentendopeptidase Clp complex
C0051117molecular_functionATPase binding
D0004176molecular_functionATP-dependent peptidase activity
D0004252molecular_functionserine-type endopeptidase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006508biological_processproteolysis
D0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
D0008236molecular_functionserine-type peptidase activity
D0009274cellular_componentpeptidoglycan-based cell wall
D0009368cellular_componentendopeptidase Clp complex
D0051117molecular_functionATPase binding
E0004176molecular_functionATP-dependent peptidase activity
E0004252molecular_functionserine-type endopeptidase activity
E0005515molecular_functionprotein binding
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0005886cellular_componentplasma membrane
E0006508biological_processproteolysis
E0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
E0008236molecular_functionserine-type peptidase activity
E0009274cellular_componentpeptidoglycan-based cell wall
E0009368cellular_componentendopeptidase Clp complex
E0051117molecular_functionATPase binding
F0004176molecular_functionATP-dependent peptidase activity
F0004252molecular_functionserine-type endopeptidase activity
F0005515molecular_functionprotein binding
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0005886cellular_componentplasma membrane
F0006508biological_processproteolysis
F0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
F0008236molecular_functionserine-type peptidase activity
F0009274cellular_componentpeptidoglycan-based cell wall
F0009368cellular_componentendopeptidase Clp complex
F0051117molecular_functionATPase binding
G0004176molecular_functionATP-dependent peptidase activity
G0004252molecular_functionserine-type endopeptidase activity
G0005515molecular_functionprotein binding
G0005737cellular_componentcytoplasm
G0005829cellular_componentcytosol
G0005886cellular_componentplasma membrane
G0006508biological_processproteolysis
G0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
G0008236molecular_functionserine-type peptidase activity
G0009274cellular_componentpeptidoglycan-based cell wall
G0009368cellular_componentendopeptidase Clp complex
G0051117molecular_functionATPase binding
H0004176molecular_functionATP-dependent peptidase activity
H0004252molecular_functionserine-type endopeptidase activity
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0005886cellular_componentplasma membrane
H0006508biological_processproteolysis
H0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
H0008236molecular_functionserine-type peptidase activity
H0009368cellular_componentendopeptidase Clp complex
H0051117molecular_functionATPase binding
I0004176molecular_functionATP-dependent peptidase activity
I0004252molecular_functionserine-type endopeptidase activity
I0005737cellular_componentcytoplasm
I0005829cellular_componentcytosol
I0005886cellular_componentplasma membrane
I0006508biological_processproteolysis
I0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
I0008236molecular_functionserine-type peptidase activity
I0009368cellular_componentendopeptidase Clp complex
I0051117molecular_functionATPase binding
J0004176molecular_functionATP-dependent peptidase activity
J0004252molecular_functionserine-type endopeptidase activity
J0005737cellular_componentcytoplasm
J0005829cellular_componentcytosol
J0005886cellular_componentplasma membrane
J0006508biological_processproteolysis
J0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
J0008236molecular_functionserine-type peptidase activity
J0009368cellular_componentendopeptidase Clp complex
J0051117molecular_functionATPase binding
K0004176molecular_functionATP-dependent peptidase activity
K0004252molecular_functionserine-type endopeptidase activity
K0005737cellular_componentcytoplasm
K0005829cellular_componentcytosol
K0005886cellular_componentplasma membrane
K0006508biological_processproteolysis
K0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
K0008236molecular_functionserine-type peptidase activity
K0009368cellular_componentendopeptidase Clp complex
K0051117molecular_functionATPase binding
L0004176molecular_functionATP-dependent peptidase activity
L0004252molecular_functionserine-type endopeptidase activity
L0005737cellular_componentcytoplasm
L0005829cellular_componentcytosol
L0005886cellular_componentplasma membrane
L0006508biological_processproteolysis
L0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
L0008236molecular_functionserine-type peptidase activity
L0009368cellular_componentendopeptidase Clp complex
L0051117molecular_functionATPase binding
M0004176molecular_functionATP-dependent peptidase activity
M0004252molecular_functionserine-type endopeptidase activity
M0005737cellular_componentcytoplasm
M0005829cellular_componentcytosol
M0005886cellular_componentplasma membrane
M0006508biological_processproteolysis
M0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
M0008236molecular_functionserine-type peptidase activity
M0009368cellular_componentendopeptidase Clp complex
M0051117molecular_functionATPase binding
N0004176molecular_functionATP-dependent peptidase activity
N0004252molecular_functionserine-type endopeptidase activity
N0005737cellular_componentcytoplasm
N0005829cellular_componentcytosol
N0005886cellular_componentplasma membrane
N0006508biological_processproteolysis
N0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
N0008236molecular_functionserine-type peptidase activity
N0009368cellular_componentendopeptidase Clp complex
N0051117molecular_functionATPase binding
a0004176molecular_functionATP-dependent peptidase activity
a0004252molecular_functionserine-type endopeptidase activity
a0005515molecular_functionprotein binding
a0005737cellular_componentcytoplasm
a0005829cellular_componentcytosol
a0005886cellular_componentplasma membrane
a0006508biological_processproteolysis
a0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
a0008236molecular_functionserine-type peptidase activity
a0009274cellular_componentpeptidoglycan-based cell wall
a0009368cellular_componentendopeptidase Clp complex
a0051117molecular_functionATPase binding
b0004176molecular_functionATP-dependent peptidase activity
b0004252molecular_functionserine-type endopeptidase activity
b0005515molecular_functionprotein binding
b0005737cellular_componentcytoplasm
b0005829cellular_componentcytosol
b0005886cellular_componentplasma membrane
b0006508biological_processproteolysis
b0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
b0008236molecular_functionserine-type peptidase activity
b0009274cellular_componentpeptidoglycan-based cell wall
b0009368cellular_componentendopeptidase Clp complex
b0051117molecular_functionATPase binding
c0004176molecular_functionATP-dependent peptidase activity
c0004252molecular_functionserine-type endopeptidase activity
c0005515molecular_functionprotein binding
c0005737cellular_componentcytoplasm
c0005829cellular_componentcytosol
c0005886cellular_componentplasma membrane
c0006508biological_processproteolysis
c0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
c0008236molecular_functionserine-type peptidase activity
c0009274cellular_componentpeptidoglycan-based cell wall
c0009368cellular_componentendopeptidase Clp complex
c0051117molecular_functionATPase binding
d0004176molecular_functionATP-dependent peptidase activity
d0004252molecular_functionserine-type endopeptidase activity
d0005515molecular_functionprotein binding
d0005737cellular_componentcytoplasm
d0005829cellular_componentcytosol
d0005886cellular_componentplasma membrane
d0006508biological_processproteolysis
d0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
d0008236molecular_functionserine-type peptidase activity
d0009274cellular_componentpeptidoglycan-based cell wall
d0009368cellular_componentendopeptidase Clp complex
d0051117molecular_functionATPase binding
e0004176molecular_functionATP-dependent peptidase activity
e0004252molecular_functionserine-type endopeptidase activity
e0005515molecular_functionprotein binding
e0005737cellular_componentcytoplasm
e0005829cellular_componentcytosol
e0005886cellular_componentplasma membrane
e0006508biological_processproteolysis
e0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
e0008236molecular_functionserine-type peptidase activity
e0009274cellular_componentpeptidoglycan-based cell wall
e0009368cellular_componentendopeptidase Clp complex
e0051117molecular_functionATPase binding
f0004176molecular_functionATP-dependent peptidase activity
f0004252molecular_functionserine-type endopeptidase activity
f0005515molecular_functionprotein binding
f0005737cellular_componentcytoplasm
f0005829cellular_componentcytosol
f0005886cellular_componentplasma membrane
f0006508biological_processproteolysis
f0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
f0008236molecular_functionserine-type peptidase activity
f0009274cellular_componentpeptidoglycan-based cell wall
f0009368cellular_componentendopeptidase Clp complex
f0051117molecular_functionATPase binding
g0004176molecular_functionATP-dependent peptidase activity
g0004252molecular_functionserine-type endopeptidase activity
g0005515molecular_functionprotein binding
g0005737cellular_componentcytoplasm
g0005829cellular_componentcytosol
g0005886cellular_componentplasma membrane
g0006508biological_processproteolysis
g0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
g0008236molecular_functionserine-type peptidase activity
g0009274cellular_componentpeptidoglycan-based cell wall
g0009368cellular_componentendopeptidase Clp complex
g0051117molecular_functionATPase binding
h0004176molecular_functionATP-dependent peptidase activity
h0004252molecular_functionserine-type endopeptidase activity
h0005737cellular_componentcytoplasm
h0005829cellular_componentcytosol
h0005886cellular_componentplasma membrane
h0006508biological_processproteolysis
h0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
h0008236molecular_functionserine-type peptidase activity
h0009368cellular_componentendopeptidase Clp complex
h0051117molecular_functionATPase binding
i0004176molecular_functionATP-dependent peptidase activity
i0004252molecular_functionserine-type endopeptidase activity
i0005737cellular_componentcytoplasm
i0005829cellular_componentcytosol
i0005886cellular_componentplasma membrane
i0006508biological_processproteolysis
i0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
i0008236molecular_functionserine-type peptidase activity
i0009368cellular_componentendopeptidase Clp complex
i0051117molecular_functionATPase binding
j0004176molecular_functionATP-dependent peptidase activity
j0004252molecular_functionserine-type endopeptidase activity
j0005737cellular_componentcytoplasm
j0005829cellular_componentcytosol
j0005886cellular_componentplasma membrane
j0006508biological_processproteolysis
j0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
j0008236molecular_functionserine-type peptidase activity
j0009368cellular_componentendopeptidase Clp complex
j0051117molecular_functionATPase binding
k0004176molecular_functionATP-dependent peptidase activity
k0004252molecular_functionserine-type endopeptidase activity
k0005737cellular_componentcytoplasm
k0005829cellular_componentcytosol
k0005886cellular_componentplasma membrane
k0006508biological_processproteolysis
k0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
k0008236molecular_functionserine-type peptidase activity
k0009368cellular_componentendopeptidase Clp complex
k0051117molecular_functionATPase binding
l0004176molecular_functionATP-dependent peptidase activity
l0004252molecular_functionserine-type endopeptidase activity
l0005737cellular_componentcytoplasm
l0005829cellular_componentcytosol
l0005886cellular_componentplasma membrane
l0006508biological_processproteolysis
l0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
l0008236molecular_functionserine-type peptidase activity
l0009368cellular_componentendopeptidase Clp complex
l0051117molecular_functionATPase binding
m0004176molecular_functionATP-dependent peptidase activity
m0004252molecular_functionserine-type endopeptidase activity
m0005737cellular_componentcytoplasm
m0005829cellular_componentcytosol
m0005886cellular_componentplasma membrane
m0006508biological_processproteolysis
m0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
m0008236molecular_functionserine-type peptidase activity
m0009368cellular_componentendopeptidase Clp complex
m0051117molecular_functionATPase binding
n0004176molecular_functionATP-dependent peptidase activity
n0004252molecular_functionserine-type endopeptidase activity
n0005737cellular_componentcytoplasm
n0005829cellular_componentcytosol
n0005886cellular_componentplasma membrane
n0006508biological_processproteolysis
n0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
n0008236molecular_functionserine-type peptidase activity
n0009368cellular_componentendopeptidase Clp complex
n0051117molecular_functionATPase binding
Functional Information from PROSITE/UniProt
site_idPS00381
Number of Residues12
DetailsCLP_PROTEASE_SER Endopeptidase Clp serine active site. TvcLGqAASAAA
ChainResidueDetails
ATHR102-ALA113

site_idPS00382
Number of Residues14
DetailsCLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RmalPnarVLIHQP
ChainResidueDetails
AARG124-PRO137
NARG112-PRO125

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00444
ChainResidueDetails
HSER98
jSER98
kSER98
lSER98
mSER98
nSER98
ISER98
JSER98
KSER98
LSER98
MSER98
NSER98
hSER98
iSER98

site_idSWS_FT_FI2
Number of Residues14
DetailsACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00444
ChainResidueDetails
HHIS123
jHIS123
kHIS123
lHIS123
mHIS123
nHIS123
IHIS123
JHIS123
KHIS123
LHIS123
MHIS123
NHIS123
hHIS123
iHIS123

226707

PDB entries from 2024-10-30

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