5DZK

Crystal structure of the active form of the proteolytic complex clpP1 and clpP2

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0004176	molecular_function	ATP-dependent peptidase activity
a	0004252	molecular_function	serine-type endopeptidase activity
a	0005515	molecular_function	protein binding
a	0005737	cellular_component	cytoplasm
a	0005886	cellular_component	plasma membrane
a	0006508	biological_process	proteolysis
a	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
a	0051117	molecular_function	ATPase binding
A	0004176	molecular_function	ATP-dependent peptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
A	0051117	molecular_function	ATPase binding
b	0004176	molecular_function	ATP-dependent peptidase activity
b	0004252	molecular_function	serine-type endopeptidase activity
b	0005515	molecular_function	protein binding
b	0005737	cellular_component	cytoplasm
b	0005886	cellular_component	plasma membrane
b	0006508	biological_process	proteolysis
b	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
b	0051117	molecular_function	ATPase binding
B	0004176	molecular_function	ATP-dependent peptidase activity
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0006508	biological_process	proteolysis
B	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
B	0051117	molecular_function	ATPase binding
c	0004176	molecular_function	ATP-dependent peptidase activity
c	0004252	molecular_function	serine-type endopeptidase activity
c	0005515	molecular_function	protein binding
c	0005737	cellular_component	cytoplasm
c	0005886	cellular_component	plasma membrane
c	0006508	biological_process	proteolysis
c	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
c	0051117	molecular_function	ATPase binding
C	0004176	molecular_function	ATP-dependent peptidase activity
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0006508	biological_process	proteolysis
C	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
C	0051117	molecular_function	ATPase binding
d	0004176	molecular_function	ATP-dependent peptidase activity
d	0004252	molecular_function	serine-type endopeptidase activity
d	0005515	molecular_function	protein binding
d	0005737	cellular_component	cytoplasm
d	0005886	cellular_component	plasma membrane
d	0006508	biological_process	proteolysis
d	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
d	0051117	molecular_function	ATPase binding
D	0004176	molecular_function	ATP-dependent peptidase activity
D	0004252	molecular_function	serine-type endopeptidase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005886	cellular_component	plasma membrane
D	0006508	biological_process	proteolysis
D	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
D	0051117	molecular_function	ATPase binding
e	0004176	molecular_function	ATP-dependent peptidase activity
e	0004252	molecular_function	serine-type endopeptidase activity
e	0005515	molecular_function	protein binding
e	0005737	cellular_component	cytoplasm
e	0005886	cellular_component	plasma membrane
e	0006508	biological_process	proteolysis
e	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
e	0051117	molecular_function	ATPase binding
E	0004176	molecular_function	ATP-dependent peptidase activity
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005886	cellular_component	plasma membrane
E	0006508	biological_process	proteolysis
E	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
E	0051117	molecular_function	ATPase binding
f	0004176	molecular_function	ATP-dependent peptidase activity
f	0004252	molecular_function	serine-type endopeptidase activity
f	0005515	molecular_function	protein binding
f	0005737	cellular_component	cytoplasm
f	0005886	cellular_component	plasma membrane
f	0006508	biological_process	proteolysis
f	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
f	0051117	molecular_function	ATPase binding
F	0004176	molecular_function	ATP-dependent peptidase activity
F	0004252	molecular_function	serine-type endopeptidase activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0005886	cellular_component	plasma membrane
F	0006508	biological_process	proteolysis
F	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
F	0051117	molecular_function	ATPase binding
g	0004176	molecular_function	ATP-dependent peptidase activity
g	0004252	molecular_function	serine-type endopeptidase activity
g	0005515	molecular_function	protein binding
g	0005737	cellular_component	cytoplasm
g	0005886	cellular_component	plasma membrane
g	0006508	biological_process	proteolysis
g	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
g	0051117	molecular_function	ATPase binding
G	0004176	molecular_function	ATP-dependent peptidase activity
G	0004252	molecular_function	serine-type endopeptidase activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005886	cellular_component	plasma membrane
G	0006508	biological_process	proteolysis
G	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
G	0051117	molecular_function	ATPase binding
h	0004176	molecular_function	ATP-dependent peptidase activity
h	0004252	molecular_function	serine-type endopeptidase activity
h	0005737	cellular_component	cytoplasm
h	0005886	cellular_component	plasma membrane
h	0006508	biological_process	proteolysis
h	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
h	0051117	molecular_function	ATPase binding
H	0004176	molecular_function	ATP-dependent peptidase activity
H	0004252	molecular_function	serine-type endopeptidase activity
H	0005737	cellular_component	cytoplasm
H	0005886	cellular_component	plasma membrane
H	0006508	biological_process	proteolysis
H	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
H	0051117	molecular_function	ATPase binding
i	0004176	molecular_function	ATP-dependent peptidase activity
i	0004252	molecular_function	serine-type endopeptidase activity
i	0005737	cellular_component	cytoplasm
i	0005886	cellular_component	plasma membrane
i	0006508	biological_process	proteolysis
i	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
i	0051117	molecular_function	ATPase binding
I	0004176	molecular_function	ATP-dependent peptidase activity
I	0004252	molecular_function	serine-type endopeptidase activity
I	0005737	cellular_component	cytoplasm
I	0005886	cellular_component	plasma membrane
I	0006508	biological_process	proteolysis
I	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
I	0051117	molecular_function	ATPase binding
j	0004176	molecular_function	ATP-dependent peptidase activity
j	0004252	molecular_function	serine-type endopeptidase activity
j	0005737	cellular_component	cytoplasm
j	0005886	cellular_component	plasma membrane
j	0006508	biological_process	proteolysis
j	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
j	0051117	molecular_function	ATPase binding
J	0004176	molecular_function	ATP-dependent peptidase activity
J	0004252	molecular_function	serine-type endopeptidase activity
J	0005737	cellular_component	cytoplasm
J	0005886	cellular_component	plasma membrane
J	0006508	biological_process	proteolysis
J	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
J	0051117	molecular_function	ATPase binding
k	0004176	molecular_function	ATP-dependent peptidase activity
k	0004252	molecular_function	serine-type endopeptidase activity
k	0005737	cellular_component	cytoplasm
k	0005886	cellular_component	plasma membrane
k	0006508	biological_process	proteolysis
k	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
k	0051117	molecular_function	ATPase binding
K	0004176	molecular_function	ATP-dependent peptidase activity
K	0004252	molecular_function	serine-type endopeptidase activity
K	0005737	cellular_component	cytoplasm
K	0005886	cellular_component	plasma membrane
K	0006508	biological_process	proteolysis
K	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
K	0051117	molecular_function	ATPase binding
l	0004176	molecular_function	ATP-dependent peptidase activity
l	0004252	molecular_function	serine-type endopeptidase activity
l	0005737	cellular_component	cytoplasm
l	0005886	cellular_component	plasma membrane
l	0006508	biological_process	proteolysis
l	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
l	0051117	molecular_function	ATPase binding
L	0004176	molecular_function	ATP-dependent peptidase activity
L	0004252	molecular_function	serine-type endopeptidase activity
L	0005737	cellular_component	cytoplasm
L	0005886	cellular_component	plasma membrane
L	0006508	biological_process	proteolysis
L	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
L	0051117	molecular_function	ATPase binding
m	0004176	molecular_function	ATP-dependent peptidase activity
m	0004252	molecular_function	serine-type endopeptidase activity
m	0005737	cellular_component	cytoplasm
m	0005886	cellular_component	plasma membrane
m	0006508	biological_process	proteolysis
m	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
m	0051117	molecular_function	ATPase binding
M	0004176	molecular_function	ATP-dependent peptidase activity
M	0004252	molecular_function	serine-type endopeptidase activity
M	0005737	cellular_component	cytoplasm
M	0005886	cellular_component	plasma membrane
M	0006508	biological_process	proteolysis
M	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
M	0051117	molecular_function	ATPase binding
n	0004176	molecular_function	ATP-dependent peptidase activity
n	0004252	molecular_function	serine-type endopeptidase activity
n	0005737	cellular_component	cytoplasm
n	0005886	cellular_component	plasma membrane
n	0006508	biological_process	proteolysis
n	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
n	0051117	molecular_function	ATPase binding
N	0004176	molecular_function	ATP-dependent peptidase activity
N	0004252	molecular_function	serine-type endopeptidase activity
N	0005737	cellular_component	cytoplasm
N	0005886	cellular_component	plasma membrane
N	0006508	biological_process	proteolysis
N	0006515	biological_process	protein quality control for misfolded or incompletely synthesized proteins
N	0051117	molecular_function	ATPase binding

Functional Information from PROSITE/UniProt

site_id	PS00381
Number of Residues	12
Details	CLP_PROTEASE_SER Endopeptidase Clp serine active site. TvcLGqAASAAA

Chain	Residue	Details
A	THR102-ALA113

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site_id	PS00382
Number of Residues	14
Details	CLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RyalPharILMHQP

Chain	Residue	Details
N	ARG112-PRO125
A	ARG124-PRO137

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00444","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	28
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00444","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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