5DW4
Succinyl-CoA:acetate CoA-transferase (AarCH6) bound to acetate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003986 | molecular_function | acetyl-CoA hydrolase activity |
| A | 0006083 | biological_process | acetate metabolic process |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| A | 0008410 | molecular_function | CoA-transferase activity |
| A | 0008775 | molecular_function | acetate CoA-transferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| A | 0045733 | biological_process | acetate catabolic process |
| A | 1901289 | biological_process | succinyl-CoA catabolic process |
| B | 0003986 | molecular_function | acetyl-CoA hydrolase activity |
| B | 0006083 | biological_process | acetate metabolic process |
| B | 0006084 | biological_process | acetyl-CoA metabolic process |
| B | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| B | 0008410 | molecular_function | CoA-transferase activity |
| B | 0008775 | molecular_function | acetate CoA-transferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| B | 0045733 | biological_process | acetate catabolic process |
| B | 1901289 | biological_process | succinyl-CoA catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue IMD A 601 |
| Chain | Residue |
| A | THR487 |
| A | LEU490 |
| A | SER491 |
| A | GLN494 |
| A | HOH896 |
| B | LEU486 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue IMD A 602 |
| Chain | Residue |
| A | HOH705 |
| A | HOH765 |
| A | HOH994 |
| A | VAL273 |
| A | GLY362 |
| A | LEU402 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue IMD A 603 |
| Chain | Residue |
| A | ALA419 |
| A | VAL422 |
| A | HOH703 |
| B | ALA419 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue IMD A 604 |
| Chain | Residue |
| A | ILE364 |
| A | ILE412 |
| A | HOH710 |
| A | HOH1136 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 605 |
| Chain | Residue |
| A | ARG442 |
| A | GLY443 |
| A | HOH1056 |
| B | PHE110 |
| B | ASN112 |
| B | ARG120 |
| B | ASN125 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 606 |
| Chain | Residue |
| A | THR36 |
| A | SER71 |
| A | PHE92 |
| A | THR94 |
| A | ARG228 |
| A | HOH872 |
| A | HOH1013 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 607 |
| Chain | Residue |
| A | ARG354 |
| A | HOH800 |
| B | VAL196 |
| B | ARG354 |
| B | HOH893 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue ACT B 605 |
| Chain | Residue |
| A | PHE110 |
| A | ASN112 |
| A | ARG120 |
| A | ASN125 |
| A | HOH1029 |
| B | ARG442 |
| B | GLY443 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 601 |
| Chain | Residue |
| A | VAL196 |
| A | ARG354 |
| A | HOH904 |
| B | ARG354 |
| B | HOH812 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue IMD B 602 |
| Chain | Residue |
| A | LEU486 |
| B | THR487 |
| B | LEU490 |
| B | SER491 |
| B | GLN494 |
| B | HOH847 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue ACT B 603 |
| Chain | Residue |
| B | THR36 |
| B | SER71 |
| B | PHE92 |
| B | THR94 |
| B | ARG228 |
| B | VAL270 |
| B | HOH879 |
| B | HOH900 |
| B | HOH1042 |
| B | HOH1124 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: 5-glutamyl coenzyme A thioester intermediate => ECO:0000269|PubMed:23030530 |
| Chain | Residue | Details |
| A | GLU294 | |
| B | GLU294 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23030530 |
| Chain | Residue | Details |
| A | GLY269 | |
| B | LYS408 | |
| A | ILE364 | |
| A | ASN384 | |
| A | GLY388 | |
| A | LYS408 | |
| B | GLY269 | |
| B | ILE364 | |
| B | ASN384 | |
| B | GLY388 |
