5DUH
Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Sulfoxide-bridged Oxabicyclic Heptene Sulfonate (SOBHS)-3 analog phenyl (1S,2S,4S,7S)-5,6-bis(4-hydroxy-3-methylphenyl)-7-thiabicyclo[2.2.1]hept-5-ene-2-sulfonate 7-oxide
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue 5FT A 900 |
Chain | Residue |
A | LEU346 |
A | MET421 |
A | ILE424 |
A | LEU428 |
A | GLY521 |
A | HIS524 |
A | LEU525 |
A | THR347 |
A | ALA350 |
A | GLU353 |
A | LEU384 |
A | LEU387 |
A | MET388 |
A | PHE404 |
A | GLY420 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue 5FT B 901 |
Chain | Residue |
B | LEU346 |
B | THR347 |
B | ALA350 |
B | GLU353 |
B | LEU384 |
B | LEU387 |
B | MET388 |
B | PHE404 |
B | MET421 |
B | ILE424 |
B | LEU428 |
B | GLY521 |
B | HIS524 |
B | LEU525 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
C | SER699 | |
D | SER699 | |
A | HIS524 | |
B | GLU353 | |
B | ARG394 | |
B | HIS524 | |
Chain | Residue | Details |
A | SER537 | |
B | SER537 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
Chain | Residue | Details |
A | CYS447 | |
B | CYS447 | |