5DUC
Crystal structure of M. tuberculosis EchA6 bound to ligand GSK951A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006635 | biological_process | fatty acid beta-oxidation |
| A | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006635 | biological_process | fatty acid beta-oxidation |
| B | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006635 | biological_process | fatty acid beta-oxidation |
| C | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue G51 A 301 |
| Chain | Residue |
| A | LEU75 |
| A | PHE216 |
| A | HOH416 |
| A | HIS79 |
| A | ASP83 |
| A | GLN103 |
| A | GLN107 |
| A | ASP131 |
| A | TRP133 |
| A | ALA208 |
| A | LYS213 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue G51 B 301 |
| Chain | Residue |
| B | LEU75 |
| B | HIS79 |
| B | ASP83 |
| B | GLN103 |
| B | GLN107 |
| B | ASP131 |
| B | TRP133 |
| B | PHE216 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue G51 C 301 |
| Chain | Residue |
| C | LEU75 |
| C | ILE76 |
| C | HIS79 |
| C | ASP83 |
| C | GLN103 |
| C | GLN107 |
| C | ASP131 |
| C | TRP133 |
| C | ALA208 |
| C | LYS213 |
| C | PHE216 |
Functional Information from PROSITE/UniProt
| site_id | PS00166 |
| Number of Residues | 21 |
| Details | ENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. VGaINGpaiGAGlqlaMqCDL |
| Chain | Residue | Details |
| A | VAL90-LEU110 |
