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5DU4

Crystal structure of M. tuberculosis EchA6 bound to ligand GSK366A

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0004300molecular_functionenoyl-CoA hydratase activity
A0005886cellular_componentplasma membrane
A0006631biological_processfatty acid metabolic process
A0006635biological_processfatty acid beta-oxidation
A0009274cellular_componentpeptidoglycan-based cell wall
A0016829molecular_functionlyase activity
A0016836molecular_functionhydro-lyase activity
Functional Information from PDB Data
site_idAC1
Number of Residues9
Detailsbinding site for residue 5FF A 301
ChainResidue
ALEU75
AHIS79
AASP83
AGLN103
AGLN107
AASP131
ATRP133
ALYS235
APRO237

Functional Information from PROSITE/UniProt
site_idPS00166
Number of Residues21
DetailsENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. VGaINGpaiGAGlqlaMqCDL
ChainResidueDetails
AVAL90-LEU110

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PDB entries from 2024-07-24

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