Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008615 | biological_process | pyridoxine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0033711 | molecular_function | 4-phosphoerythronate dehydrogenase activity |
| A | 0036001 | biological_process | 'de novo' pyridoxal 5'-phosphate biosynthetic process |
| A | 0046983 | molecular_function | protein dimerization activity |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | ASN98 |
| A | HIS181 |
| A | THR182 |
| A | PRO183 |
| A | TRP190 |
| A | THR192 |
| A | ALA213 |
| A | ALA214 |
| A | ARG215 |
| A | ASP239 |
| A | HIS261 |
| A | GLY130 |
| A | ALA263 |
| A | GLY264 |
| A | ALA131 |
| A | GLY132 |
| A | GLN133 |
| A | VAL134 |
| A | ASP153 |
| A | PRO154 |
| A | LYS156 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ARG65 |
| A | HIS349 |
| A | HOH518 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | ARG34 |
| A | ARG50 |
| A | LYS67 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | ARG50 |
| A | SER51 |
| A | THR73 |
| A | LYS270 |
| A | HOH568 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | VAL79 |
| A | ASP80 |
| A | GLN81 |
| A | ALA82 |
| A | HOH548 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | ASN152 |
| A | PRO154 |
| A | GLU167 |
| A | LEU168 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | ILE184 |
| A | THR185 |
| A | ARG186 |
| A | GLY187 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 408 |
| Chain | Residue |
| A | ARG272 |
| A | PRO293 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 409 |
| Chain | Residue |
| A | ASN14 |
| A | ASN64 |
| A | ARG65 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 410 |
| Chain | Residue |
| A | ARG215 |
| A | GLY216 |
| A | GLU244 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 411 |
| Chain | Residue |
| A | ALA365 |
| A | HIS368 |
| A | LEU369 |
| A | ALA370 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 412 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 413 |
Functional Information from PROSITE/UniProt
| site_id | PS00671 |
| Number of Residues | 17 |
| Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. LRsDqILINaARGpVVD |
| Chain | Residue | Details |
| A | LEU204-ASP220 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01825","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01825","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01825","evidenceCode":"ECO:0000255"}]} |
