5DQN
Polyethylene 600-bound form of P450 CYP125A3 mutant from Myobacterium Smegmatis - W83Y
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006707 | biological_process | cholesterol catabolic process |
| A | 0008202 | biological_process | steroid metabolic process |
| A | 0008203 | biological_process | cholesterol metabolic process |
| A | 0008395 | molecular_function | steroid hydroxylase activity |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | ALA79 |
| A | THR256 |
| A | PHE299 |
| A | ARG301 |
| A | TYR324 |
| A | GLY351 |
| A | PHE352 |
| A | GLY353 |
| A | GLY354 |
| A | ALA357 |
| A | HIS358 |
| A | LEU99 |
| A | TYR359 |
| A | CYS360 |
| A | ILE361 |
| A | GLY362 |
| A | LEU365 |
| A | ALA366 |
| A | 1PE505 |
| A | HOH602 |
| A | HOH604 |
| A | HOH635 |
| A | LEU100 |
| A | HIS107 |
| A | ARG111 |
| A | LEU248 |
| A | ALA251 |
| A | GLY252 |
| A | THR255 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 A 502 |
| Chain | Residue |
| A | VAL82 |
| A | PRO84 |
| A | GLY186 |
| A | GLU187 |
| A | SER395 |
| A | GLY396 |
| A | TRP397 |
| A | HOH669 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue PO4 A 503 |
| Chain | Residue |
| A | CYS155 |
| A | ASN181 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CIT A 504 |
| Chain | Residue |
| A | LEU94 |
| A | ARG96 |
| A | ALA97 |
| A | MET208 |
| A | GLU212 |
| A | ASP238 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue 1PE A 505 |
| Chain | Residue |
| A | ILE80 |
| A | GLN95 |
| A | LEU100 |
| A | VAL250 |
| A | ALA251 |
| A | HEM501 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"23489718","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4APY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DQN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
