5DQI

Crystal Structure of Human DNA Polymerase Eta Extending an O4-Ethylthymidine : dA Pair By Inserting dCTP Opposite dG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue DCP A 501

Chain	Residue
A	ASP13
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	CA502
A	CA503
A	HOH601
A	HOH607
A	HOH627
A	HOH639
A	MET14
P	DA8
P	DC9
T	DG4
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	ALA49
A	TYR52

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CA A 502

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	DCP501
A	CA503

---

site_id	AC3
Number of Residues	8
Details	binding site for residue CA A 503

Chain	Residue
A	ASP13
A	ASP115
A	GLU116
A	DCP501
A	CA502
A	HOH639
P	DA8
P	DC9

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO

Chain	Residue	Details
A	ASP13
A	MET14
A	ASP115
A	GLU116

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197

Chain	Residue	Details
A	ARG61

---